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In recent years, the advent of foundation models (FM) for digital pathology has relied heavily on scaling the pre-training datasets and the model size, yielding large and powerful models. While it resulted in improving the performance on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Alexandre Filiot , Nicolas Dop , Oussama Tchita , Auriane Riou , Rémy Dubois , Thomas Peeters , Daria Valter , Marin Scalbert , Charlie Saillard , Geneviève Robin , Antoine Olivier

Background: Tumour budding is an independent predictor of metastasis and prognosis in colorectal cancer and is a vital part of the pathology specification report. In a conventional pathological section observation process, pathologists have…

Medical Physics · Physics 2025-03-21 Yiyan Su , Ruiqing Sun , Yajing Wang , Yanfeng xi , Shaohui Zhang

Image segmentation is a long-standing challenge in computer vision, studied continuously over several decades, as evidenced by seminal algorithms such as N-Cut, FCN, and MaskFormer. With the advent of foundation models (FMs), contemporary…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Tianfei Zhou , Wang Xia , Fei Zhang , Boyu Chang , Wenguan Wang , Ye Yuan , Ender Konukoglu , Daniel Cremers

Modern foundation models provide highly expressive visual representations, yet adapting them to high-resolution medical imaging remains challenging due to limited annotations and weak supervision. Mammography, in particular, is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Nikola Jovišić , Milica Škipina , Nicola Dall'Asen , Dubravko Ćulibrk

Traditional domain generalization methods often rely on domain alignment to reduce inter-domain distribution differences and learn domain-invariant representations. However, domain shifts are inherently difficult to eliminate, which limits…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Yuheng Xu , Taiping Zhang

Image segmentation is crucial in many computational pathology pipelines, including accurate disease diagnosis, subtyping, outcome, and survivability prediction. The common approach for training a segmentation model relies on a pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Sachin Kumar Danisetty , Alexandros Graikos , Srikar Yellapragada , Dimitris Samaras

Revealing novel insights from the relationship between molecular measurements and pathology remains a very impactful application of machine learning in biomedicine. Data in this domain typically contain only a few observations but thousands…

Machine Learning · Computer Science 2026-03-31 Christopher Kolberg , Jules Kreuer , Jonas Huurdeman , Sofiane Ouaari , Katharina Eggensperger , Nico Pfeifer

Partial differential equations (PDEs) govern a wide range of physical systems, but solving them efficiently remains a major challenge. The idea of a scientific foundation model (SciFM) is emerging as a promising tool for learning…

Machine Learning · Computer Science 2025-03-26 Amin Totounferoush , Serge Kotchourko , Michael W. Mahoney , Steffen Staab

Background: The reproducibility of machine-learning models in prostate cancer detection across different MRI vendors remains a significant challenge. Methods: This study investigates Support Vector Machines (SVM) and Random Forest (RF)…

Organ morphology is a key indicator for prostate disease diagnosis and prognosis. For instance, In longitudinal study of prostate cancer patients under active surveillance, the volume, boundary smoothness and their changes are closely…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Qianye Yang , Tom Vercauteren , Yunguan Fu , Francesco Giganti , Nooshin Ghavami , Vasilis Stavrinides , Caroline Moore , Matt Clarkson , Dean Barratt , Yipeng Hu

Few-shot semantic segmentation (FSS) is a crucial challenge in computer vision, driving extensive research into a diverse range of methods, from advanced meta-learning techniques to simple transfer learning baselines. With the emergence of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Reda Bensaid , Vincent Gripon , François Leduc-Primeau , Lukas Mauch , Ghouthi Boukli Hacene , Fabien Cardinaux

Whole Slide Images (WSIs) are giga-pixel in scale and are typically partitioned into small instances in WSI classification pipelines for computational feasibility. However, obtaining extensive instance level annotations is costly, making…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jayanie Bogahawatte , Sachith Seneviratne , Saman Halgamuge

This review examines the current state of research on microscale cellular changes during the drying of plant-based food materials (PBFM), with particular emphasis on computational modelling approaches. The review addresses the critical need…

Machine Learning · Computer Science 2025-01-17 C. P. Batuwatta-Gamage , H. Jeong , HCP Karunasena , M. A. Karim , C. M. Rathnayaka , Y. T. Gu

Deep Learning-based computational pathology algorithms have demonstrated profound ability to excel in a wide array of tasks that range from characterization of well known morphological phenotypes to predicting non-human-identifiable…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Ming Y. Lu , Dehan Kong , Jana Lipkova , Richard J. Chen , Rajendra Singh , Drew F. K. Williamson , Tiffany Y. Chen , Faisal Mahmood

Deep learning underlies most modern approaches and tools in computer vision, including biomedical imaging. However, for interactive semantic segmentation (often called pixel classification in this context) and interactive object-level…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Carolin Teuber , Anwai Archit , Tobias Boothe , Peter Ditte , Jochen Rink , Constantin Pape

Early prostate cancer detection and staging from MRI are extremely challenging tasks for both radiologists and deep learning algorithms, but the potential to learn from large and diverse datasets remains a promising avenue to increase their…

Computer Vision and Pattern Recognition · Computer Science 2022-06-14 Abhejit Rajagopal , Ekaterina Redekop , Anil Kemisetti , Rushi Kulkarni , Steven Raman , Kirti Magudia , Corey W. Arnold , Peder E. Z. Larson

Vision foundation models (FMs) have become the predominant architecture in computer vision, providing highly transferable representations learned from large-scale, multimodal corpora. Nonetheless, they exhibit persistent limitations on…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Fatemeh Ziaeetabar

The study of histopathological subtypes is valuable for the personalisation of effective treatment strategies for ovarian cancer. However, increasing diagnostic workloads present a challenge for UK pathology departments, leading to the rise…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Marcus Jenkins , Jasenka Mazibrada , Bogdan Leahu , Michal Mackiewicz

Magnetic resonance imaging (MRI) requires long acquisition times, raising costs, reducing accessibility, and making scans more susceptible to motion artifacts. Diffusion probabilistic models that learn data-driven priors can potentially…

Image and Video Processing · Electrical Eng. & Systems 2025-12-16 Rohan Sanda , Asad Aali , Andrew Johnston , Eduardo Reis , Gordon Wetzstein , Sara Fridovich-Keil

Deep Neural Networks have shown promising classification performance when predicting certain biomarkers from Whole Slide Images in digital pathology. However, the calibration of the networks' output probabilities is often not evaluated.…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Alexander Kurz , Hendrik A. Mehrtens , Tabea-Clara Bucher , Titus J. Brinker