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Recent advancements in biology and chemistry have leveraged multi-modal learning, integrating molecules and their natural language descriptions to enhance drug discovery. However, current pre-training frameworks are limited to two…

Machine Learning · Computer Science 2025-02-05 Teng Xiao , Chao Cui , Huaisheng Zhu , Vasant G. Honavar

Alzheimer's disease (AD) is an incurable neurodegenerative condition leading to cognitive and functional deterioration. Given the lack of a cure, prompt and precise AD diagnosis is vital, a complex process dependent on multiple factors and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Guangqian Yang , Kangrui Du , Zhihan Yang , Ye Du , Yongping Zheng , Shujun Wang

The integration of different imaging modalities, such as structural, diffusion tensor, and functional magnetic resonance imaging, with deep learning models has yielded promising outcomes in discerning phenotypic characteristics and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Zhiyuan Li , Hailong Li , Anca L. Ralescu , Jonathan R. Dillman , Mekibib Altaye , Kim M. Cecil , Nehal A. Parikh , Lili He

A unified representation space in multi-modal learning is essential for effectively integrating diverse data sources, such as text, images, and audio, to enhance efficiency and performance across various downstream tasks. Recent binding…

Machine Learning · Computer Science 2025-10-08 Minoh Jeong , Zae Myung Kim , Min Namgung , Dongyeop Kang , Yao-Yi Chiang , Alfred Hero

Image-text multimodal representation learning aligns data across modalities and enables important medical applications, e.g., image classification, visual grounding, and cross-modal retrieval. In this work, we establish a connection between…

Computer Vision and Pattern Recognition · Computer Science 2023-06-14 Peiqi Wang , William M. Wells , Seth Berkowitz , Steven Horng , Polina Golland

Multimodal models, such as the Contrastive Language-Image Pre-training (CLIP) model, have demonstrated remarkable success in aligning visual and linguistic representations. However, these models exhibit limitations when applied to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-02 Hiroshi Sasaki

Introspection of deep supervised predictive models trained on functional and structural brain imaging may uncover novel markers of Alzheimer's disease (AD). However, supervised training is prone to learning from spurious features (shortcut…

Machine Learning · Computer Science 2022-05-24 Alex Fedorov , Lei Wu , Tristan Sylvain , Margaux Luck , Thomas P. DeRamus , Dmitry Bleklov , Sergey M. Plis , Vince D. Calhoun

Recent multimodal models such as Contrastive Language-Image Pre-training (CLIP) have shown remarkable ability to align visual and linguistic representations. However, domains where small visual differences carry large semantic significance,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Hiroshi Sasaki

Multi-view representation learning has developed rapidly over the past decades and has been applied in many fields. However, most previous works assumed that each view is complete and aligned. This leads to an inevitable deterioration in…

Computer Vision and Pattern Recognition · Computer Science 2022-11-10 Yiming Wang , Dongxia Chang , Zhiqiang Fu , Jie Wen , Yao Zhao

Artificial intelligence for graphs has achieved remarkable success in modeling complex systems, ranging from dynamic networks in biology to interacting particle systems in physics. However, the increasingly heterogeneous graph datasets call…

Machine Learning · Computer Science 2023-01-25 Yasha Ektefaie , George Dasoulas , Ayush Noori , Maha Farhat , Marinka Zitnik

Modern Review Helpfulness Prediction systems are dependent upon multiple modalities, typically texts and images. Unfortunately, those contemporary approaches pay scarce attention to polish representations of cross-modal relations and tend…

Computation and Language · Computer Science 2026-05-13 Thong Nguyen , Xiaobao Wu , Anh-Tuan Luu , Cong-Duy Nguyen , Zhen Hai , Lidong Bing

As medical diagnoses increasingly leverage multimodal data, machine learning models are expected to effectively fuse heterogeneous information while remaining robust to missing modalities. In this work, we propose a novel multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Yi Gu , Kuniaki Saito , Jiaxin Ma

Alongside neuroimaging such as MRI scans and PET, Alzheimer's disease (AD) datasets contain valuable tabular data including AD biomarkers and clinical assessments. Existing computer vision approaches struggle to utilize this additional…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Weichen Huang

We develop an approach to learning visual representations that embraces multimodal data, driven by a combination of intra- and inter-modal similarity preservation objectives. Unlike existing visual pre-training methods, which solve a proxy…

Computer Vision and Pattern Recognition · Computer Science 2021-04-28 Xin Yuan , Zhe Lin , Jason Kuen , Jianming Zhang , Yilin Wang , Michael Maire , Ajinkya Kale , Baldo Faieta

Sensory input from multiple sources is crucial for robust and coherent human perception. Different sources contribute complementary explanatory factors. Similarly, research studies often collect multimodal imaging data, each of which can…

Multimodal learning for generative models often refers to the learning of abstract concepts from the commonality of information in multiple modalities, such as vision and language. While it has proven effective for learning generalisable…

Machine Learning · Computer Science 2021-04-22 Yuge Shi , Brooks Paige , Philip H. S. Torr , N. Siddharth

In this paper, we introduce a self-supervised learning method to enhance the graph-level representations with the help of a set of subgraphs. For this purpose, we propose a universal framework to generate subgraphs in an auto-regressive way…

Machine Learning · Computer Science 2021-05-10 Chenguang Wang , Ziwen Liu

Contrastive learning has been widely applied to graph representation learning, where the view generators play a vital role in generating effective contrastive samples. Most of the existing contrastive learning methods employ pre-defined…

Machine Learning · Computer Science 2022-01-04 Yihang Yin , Qingzhong Wang , Siyu Huang , Haoyi Xiong , Xiang Zhang

Learning from multimodal data is an important research topic in machine learning, which has the potential to obtain better representations. In this work, we propose a novel approach to generative modeling of multimodal data based on…

Machine Learning · Computer Science 2021-12-21 Wenxue Chen , Jianke Zhu

The recent advent of self-supervised pre-training techniques has led to a surge in the use of multimodal learning in form document understanding. However, existing approaches that extend the mask language modeling to other modalities…

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