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Since its foundations, more than one hundred years ago, the field of structural biology has strived to understand and analyze the properties of molecules and their interactions by studying the structure that they take in 3D space. However,…

Biomolecules · Quantitative Biology 2023-02-27 Gabriele Corso

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Jian-Qing Zheng , Yuanhan Mo , Yang Sun , Jiahua Li , Fuping Wu , Ziyang Wang , Tonia Vincent , Bartłomiej W. Papież

Seismic imaging from sparsely acquired data faces challenges such as low image quality, discontinuities, and migration swing artifacts. Existing convolutional neural network (CNN)-based methods struggle with complex feature distributions…

Geophysics · Physics 2024-08-01 Xingchen Shi , Shijun Cheng , Weijian Mao , Wei Ouyang

Deep generative models such as diffusion and flow matching are powerful machine learning tools capable of learning and sampling from high-dimensional distributions. They are particularly useful when the training data appears to be…

High Energy Physics - Phenomenology · Physics 2026-04-30 Zachary Bogorad , Ibrahim Elsharkawy , Yonatan Kahn , Andrew J. Larkoski , Noam Levi

Recent advancements in deep learning for medical image segmentation are often limited by the scarcity of high-quality training data.While diffusion models provide a potential solution by generating synthetic images, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Jianhao Xie , Ziang Zhang , Zhenyu Weng , Yuesheng Zhu , Guibo Luo

Latent diffusion models (LDMs) dominate high-quality image generation, yet integrating representation learning with generative modeling remains a challenge. We introduce a novel generative image modeling framework that seamlessly bridges…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Theodoros Kouzelis , Efstathios Karypidis , Ioannis Kakogeorgiou , Spyros Gidaris , Nikos Komodakis

Diffusion models suffer from slow sample generation at inference time. Therefore, developing a principled framework for fast deterministic/stochastic sampling for a broader class of diffusion models is a promising direction. We propose two…

Machine Learning · Computer Science 2023-10-13 Kushagra Pandey , Maja Rudolph , Stephan Mandt

Real-world databases are predominantly relational, comprising multiple interlinked tables that contain complex structural and statistical dependencies. Learning generative models on relational data has shown great promise in generating…

Machine Learning · Computer Science 2025-06-03 Valter Hudovernik , Minkai Xu , Juntong Shi , Lovro Šubelj , Stefano Ermon , Erik Štrumbelj , Jure Leskovec

This paper proposes a supervised training algorithm for learning stochastic resource allocation policies with generative diffusion models (GDMs). We formulate the allocation problem as the maximization of an ergodic utility function subject…

Machine Learning · Computer Science 2025-09-23 Yigit Berkay Uslu , Samar Hadou , Shirin Saeedi Bidokhti , Alejandro Ribeiro

Fairness is an important topic for medical image analysis, driven by the challenge of unbalanced training data among diverse target groups and the societal demand for equitable medical quality. In response to this issue, our research adopts…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Wenyi Li , Haoran Xu , Guiyu Zhang , Huan-ang Gao , Mingju Gao , Mengyu Wang , Hao Zhao

Diffusion models have shown remarkable success across a wide range of generative tasks. However, they often suffer from spatially inconsistent generation, arguably due to the inherent locality of their denoising mechanisms. This can yield…

Machine Learning · Computer Science 2026-02-04 Wenshuai Zhao , Zhiyuan Li , Yi Zhao , Mohammad Hassan Vali , Martin Trapp , Joni Pajarinen , Juho Kannala , Arno Solin

Temporally consistent video-to-video generation is critical for applications such as style transfer and upsampling. In this paper, we provide a theoretical analysis of warped noise - a recently proposed technique for training video…

Computer Vision and Pattern Recognition · Computer Science 2025-10-17 Chao Liu , Arash Vahdat

The proposed BSDE-based diffusion model represents a novel approach to diffusion modeling, which extends the application of stochastic differential equations (SDEs) in machine learning. Unlike traditional SDE-based diffusion models, our…

Machine Learning · Computer Science 2023-04-27 Zihao Wang

We propose GRAM-DIFF, a Gram-matrix-guided diffusion framework for semi-blind multiple input multiple output (MIMO) channel estimation. Recent diffusion-based estimators leverage learned generative priors to improve pilot-based channel…

Information Theory · Computer Science 2026-02-18 Xinyuan Wang , Krishna Narayanan

Dataset distillation aims to synthesize a compact subset of the original data, enabling models trained on it to achieve performance comparable to those trained on the original large dataset. Existing distribution-matching methods are…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Xuhui Li , Zhengquan Luo , Zihui Cui , Zhiqiang Xu

Acquiring high-quality data for training discriminative models is a crucial yet challenging aspect of building effective predictive systems. In this paper, we present Diffusion Inversion, a simple yet effective method that leverages the…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Yongchao Zhou , Hshmat Sahak , Jimmy Ba

Diffusion models have achieved remarkable success in high-fidelity image generation but remain computationally demanding due to their multi-step denoising process and large model sizes. Although prior work improves efficiency either by…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Zongfang Liu , Shengkun Tang , Zongliang Wu , Xin Yuan , Zhiqiang Shen

We present a new algorithm to optimize distributions defined implicitly by parameterized stochastic diffusions. Doing so allows us to modify the outcome distribution of sampling processes by optimizing over their parameters. We introduce a…

Structure-based drug design (SBDD) aims to design small-molecule ligands that bind with high affinity and specificity to pre-determined protein targets. Generative SBDD methods leverage structural data of drugs in complex with their protein…

Controllable spherical panoramic image generation holds substantial applicative potential across a variety of domains.However, it remains a challenging task due to the inherent spherical distortion and geometry characteristics, resulting in…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Tao Wu , Xuewei Li , Zhongang Qi , Di Hu , Xintao Wang , Ying Shan , Xi Li