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Measuring the statistical dependence between observed signals is a primary tool for scientific discovery. However, biological systems often exhibit complex non-linear interactions that currently cannot be captured without a priori knowledge…

The remarkable performance of modern AI systems has been driven by unprecedented scales of data, computation, and energy -- far exceeding the resources required by human intelligence. This disparity highlights the need for new guiding…

Artificial Intelligence · Computer Science 2026-02-24 Alessandro Salatiello

Inducing causal relationships from observations is a classic problem in machine learning. Most work in causality starts from the premise that the causal variables themselves are observed. However, for AI agents such as robots trying to make…

Generative models can be trained to emulate complex empirical data, but are they useful to make predictions in the context of previously unobserved environments? An intuitive idea to promote such extrapolation capabilities is to have the…

Machine Learning · Computer Science 2022-01-03 Michel Besserve , Rémy Sun , Dominik Janzing , Bernhard Schölkopf

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

Neurons and Cognition · Quantitative Biology 2020-12-02 Hui Wei

In modern applications, statisticians are faced with integrating heterogeneous data modalities relevant for an inference, prediction, or decision problem. In such circumstances, it is convenient to use a graphical model to represent the…

Methodology · Statistics 2017-08-30 Pierre E. Jacob , Lawrence M. Murray , Chris C. Holmes , Christian P. Robert

Comparing the internal representations of neural networks is a central goal in both neuroscience and machine learning. Standard alignment metrics operate on raw neural activations, implicitly assuming that similar representations produce…

Machine Learning · Computer Science 2026-04-02 Sunny Liu , Habon Issa , André Longon , Liv Gorton , Meenakshi Khosla , David Klindt

Animals learn to predict external contingencies from experience through a process of conditioning. A natural mechanism for conditioning is stimulus substitution, whereby the neuronal response to a stimulus with no prior behavioral…

Neurons and Cognition · Quantitative Biology 2024-09-23 Pantelis Vafidis , Antonio Rangel

The problem of balancing conflicting needs is fundamental to intelligence. Standard reinforcement learning algorithms maximize a scalar reward, which requires combining different objective-specific rewards into a single number.…

Machine Learning · Computer Science 2022-04-15 Zack Dulberg , Rachit Dubey , Isabel M. Berwian , Jonathan D. Cohen

Recent research revealed a considerable lack of reliability for user feedback when interacting with adaptive systems, often denoted as user noise or human uncertainty. Moreover, this lack of reliability holds striking impacts for the…

Human-Computer Interaction · Computer Science 2018-05-01 Kevin Jasberg , Sergej Sizov

Biological systems exhibit two structural features on many levels of organization: sparseness, in which only a small fraction of possible interactions between components actually occur; and modularity - the near decomposability of the…

Molecular Networks · Quantitative Biology 2013-12-25 Tamar Friedlander , Avraham E. Mayo , Tsvi Tlusty , Uri Alon

Stimulus from the environment that guides behavior and informs decisions is encoded in the firing rates of neural populations. Each neuron in the populations, however, does not spike independently: spike events are correlated from cell to…

Neurons and Cognition · Quantitative Biology 2012-07-24 Nicholas Cain , Eric Shea-Brown

Multi-agent systems in biology, society, and engineering are capable of making decisions through the dynamic interaction of their elements. Nonlinearity of the interactions is key for the speed, robustness, and flexibility of multi-agent…

Dynamical Systems · Mathematics 2024-10-02 Rodrigo Moreno-Morton , Anastasia Bizyaeva , Naomi Ehrich Leonard , Alessio Franci

Encoding models are used for predicting brain activity in response to sensory stimuli with the objective of elucidating how sensory information is represented in the brain. Encoding models typically comprise a nonlinear transformation of…

Neurons and Cognition · Quantitative Biology 2017-03-13 Umut Güçlü , Marcel A. J. van Gerven

In this paper we consider the neuroscientific theory of the Bayesian brain in the light of adaptive web systems and content personalisation. In particular, we elaborate on neural mechanisms of human decision-making and the origin of lacking…

Human-Computer Interaction · Computer Science 2018-02-19 Kevin Jasberg , Sergej Sizov

In many scientific contexts, different investigators experiment with or observe different variables with data from a domain in which the distinct variable sets might well be related. This sort of fragmentation sometimes occurs in molecular…

Artificial Intelligence · Computer Science 2019-09-05 Shuyan Wang

Neural networks exhibit a remarkable degree of representational convergence across diverse architectures, training objectives, and even data modalities. This convergence is predictive of alignment with brain representation. A recent…

Neurons and Cognition · Quantitative Biology 2026-04-24 Eghbal A. Hosseini , Brian Cheung , Evelina Fedorenko , Alex H. Williams

Understanding how human brains interpret and process information is important. Here, we investigated the selectivity and inter-individual differences in human brain responses to images via functional MRI. In our first experiment, we found…

Quantitative Methods · Quantitative Biology 2023-04-20 Zijin Gu , Keith Jamison , Mert R. Sabuncu , Amy Kuceyeski

From the point of view of the human brain, continual learning can perform various tasks without mutual interference. An effective way to reduce mutual interference can be found in sparsity and selectivity of neurons. According to Aljundi et…

Machine Learning · Computer Science 2024-10-04 Jin Hyun Park

Existing multi-behavior recommendations tend to prioritize performance at the expense of explainability, while current explainable methods suffer from limited generalizability due to their reliance on external information. Neuro-Symbolic…

Artificial Intelligence · Computer Science 2026-01-30 Yuzhe Chen , Jie Cao , Youquan Wang , Haicheng Tao , Darko B. Vukovic , Jia Wu