English
Related papers

Related papers: Information Clustering and Pathogen Evolution

200 papers

To cluster data is to separate samples into distinctive groups that should ideally have some cohesive properties. Today, numerous clustering algorithms exist, and their differences lie essentially in what can be perceived as ``cohesive…

Machine Learning · Statistics 2025-05-08 Louis Ohl , Pierre-Alexandre Mattei , Frédéric Precioso

In many practical applications of clustering, the objects to be clustered evolve over time, and a clustering result is desired at each time step. In such applications, evolutionary clustering typically outperforms traditional static…

Machine Learning · Computer Science 2015-03-19 Kevin S. Xu , Mark Kliger , Alfred O. Hero

Motivated by the analysis of social networks, we study a model of random networks that has both a given degree distribution and a tunable clustering coefficient. We consider two types of growth processes on these graphs: diffusion and…

Probability · Mathematics 2012-02-23 Emilie Coupechoux , Marc Lelarge

The COVID-19 pandemic has taken the world by storm with its high infection rate. Investigating its geographical disparities has paramount interest in order to gauge its relationships with political decisions, economic indicators, or mental…

Applications · Statistics 2023-12-29 Amay SM Cheam , Marc Fredette , Matthieu Marbac , Fabien Navarro

It is well recognised that animal and plant pathogens form complex ecological communities of interacting organisms within their hosts. Although community ecology approaches have been applied to determine pathogen interactions at the…

We consider the dynamics of a virus spreading through a population that produces a mutant strain with the ability to infect individuals that were infected with the established strain. Temporary cross-immunity is included using a time delay,…

Populations and Evolution · Quantitative Biology 2023-02-16 Bruce Pell , Samantha Brozak , Tin Phan , Fuqing Wu , Yang Kuang

The spread of an infectious disease can be promoted by previous infections with other pathogens. This cooperative effect can give rise to violent outbreaks, reflecting the presence of an abrupt epidemic transition. As for other diffusive…

Physics and Society · Physics 2019-02-06 Peng-Bi Cui , Francesca Colaiori , Claudio Castellano

Viral mutations pose significant threats to public health by increasing infectivity, strengthening vaccine resistance, and altering disease severity. To track these evolving patterns, agencies like the CDC annually evaluate thousands of…

Populations and Evolution · Quantitative Biology 2025-04-07 Emilee Walden , Jiahui Chen , Guo-Wei Wei

In heterogeneous disorders like Parkinson's disease (PD), differentiating the affected population into subgroups plays a key role in future research. Discovering subgroups can lead to improved treatments through more powerful enrichment of…

Methodology · Statistics 2023-08-08 Elliot Burghardt , Daniel Sewell , Joseph Cavanaugh

We consider the problem of model-based clustering in the presence of many correlated, mixed continuous and discrete variables, some of which may have missing values. Discrete variables are treated with a latent continuous variable approach…

In many fields, researchers are interested in large and complex biological processes. Two important examples are gene expression and DNA methylation in genetics. One key problem is to identify aberrant patterns of these processes and…

Applications · Statistics 2012-10-03 Matthias Kormaksson , James G. Booth , Maria E. Figueroa , Ari Melnick

Recent advances in engineering technologies have enabled the collection of a large number of longitudinal features. This wealth of information presents unique opportunities for researchers to investigate the complex nature of diseases and…

Methodology · Statistics 2023-11-27 Zihang Lu , Noirrit Kiran Chandra

Motile organisms can form stable agglomerates such as cities or colonies. In the outbreak of a highly contagious disease, the control of large-scale epidemic spread depends on factors like the number and size of agglomerates, travel rate…

Populations and Evolution · Quantitative Biology 2023-04-03 Pablo de Castro , Felipe Urbina , Ariel Norambuena , Francisca Guzmán-Lastra

can evolve simultaneously. For the information-driven adaptive process, susceptible (infected) individuals who have abilities to recognize the disease would break the links of their infected (susceptible) neighbors to prevent the epidemic…

Physics and Society · Physics 2015-05-20 Xiu-Xiu Zhan , Chuang Liu , Gui-Quan Sun , Zi-Ke Zhang

Conventional survival analysis approaches estimate risk scores or individualized time-to-event distributions conditioned on covariates. In practice, there is often great population-level phenotypic heterogeneity, resulting from (unknown)…

Machine Learning · Statistics 2020-03-03 Paidamoyo Chapfuwa , Chunyuan Li , Nikhil Mehta , Lawrence Carin , Ricardo Henao

Multivariate time-dependent data, where multiple features are observed over time for a set of individuals, are increasingly widespread in many application domains. To model these data we need to account for relations among both time…

Methodology · Statistics 2021-04-08 Alessandro Casa , Charles Bouveyron , Elena Erosheva , Giovanna Menardi

Clustering is one of the most fundamental tools in the artificial intelligence area, particularly in the pattern recognition and learning theory. In this paper, we propose a simple, but novel approach for variance-based k-clustering tasks,…

Machine Learning · Computer Science 2020-09-17 Yicheng Xu , Vincent Chau , Chenchen Wu , Yong Zhang , Vassilis Zissimopoulos , Yifei Zou

Coinfection is the process by which a host that is infected with a pathogen becomes infected by a second pathogen at a later point in time. An immunosuppressant host response to a primary disease can facilitate spreading of a subsequent…

Physics and Society · Physics 2021-04-14 Peter Mann , Anne Smith , John Mitchell , Simon Dobson

Epidemic outbreaks of new pathogens, or known pathogens in new populations, cause a great deal of fear because they are hard to predict. For theoretical models of disease spreading, on the other hand, quantities characterizing the outbreak…

Populations and Evolution · Quantitative Biology 2015-05-20 Petter Holme , Taro Takaguchi

Non-pharmaceutical measures such as preventive quarantines, remote working, school and workplace closures, lockdowns, etc. have shown effectivenness from an epidemic control perspective; however they have also significant negative…