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The properties of functional brain networks strongly depend on how their nodes are chosen. Commonly, nodes are defined by Regions of Interest (ROIs), pre-determined groupings of fMRI measurement voxels. Earlier, we have demonstrated that…

Neurons and Cognition · Quantitative Biology 2019-11-25 Elisa Ryyppö , Enrico Glerean , Elvira Brattico , Jari Saramäki , Onerva Korhonen

The functional network approach, where fMRI BOLD time series are mapped to networks depicting functional relationships between brain areas, has opened new insights into the function of the human brain. In this approach, the choice of…

Neurons and Cognition · Quantitative Biology 2017-11-10 Onerva Korhonen , Heini Saarimäki , Enrico Glerean , Mikko Sams , Jari Saramäki

Human brains are commonly modeled as networks of Regions of Interest (ROIs) and their connections for the understanding of brain functions and mental disorders. Recently, Transformer-based models have been studied over different types of…

Machine Learning · Computer Science 2022-10-18 Xuan Kan , Wei Dai , Hejie Cui , Zilong Zhang , Ying Guo , Carl Yang

The human brain can be conceptualized as a dynamical system. Utilizing resting state fMRI time series imaging, we can study the underlying dynamics at ear-marked Regions of Interest (ROIs) to understand structure or lack thereof. This…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Ninad Aithal , Chakka Sai Pradeep , Neelam Sinha

Brain connectome analysis commonly compresses high-resolution brain scans (typically composed of millions of voxels) down to only hundreds of regions of interest (ROIs) by averaging within-ROI signals. This huge dimension reduction improves…

Methodology · Statistics 2025-03-25 Tong Lu , Yuan Zhang , Peter Kochunov , Elliot Hong , Shuo Chen

In this study, we present a technique that spans multi-scale views (global scale -- meaning brain network-level and local scale -- examining each individual ROI that constitutes the network) applied to resting-state fMRI volumes. Deep…

Computer Vision and Pattern Recognition · Computer Science 2024-02-07 Ammu R. , Debanjali Bhattacharya , Ameiy Acharya , Ninad Aithal , Neelam Sinha

Human brain dynamics can be profitably viewed through the lens of statistical mechanics, where neurophysiological activity evolves around and between local attractors representing preferred mental states. Many physically-inspired models of…

Neurons and Cognition · Quantitative Biology 2016-09-06 Arian Ashourvan , Shi Gu , Marcelo G. Mattar , Jean M. Vettel , Danielle S. Bassett

The release of large datasets and developments in AI have led to dramatic improvements in decoding methods that reconstruct seen images from human brain activity. We evaluate the prospect of further improving recent decoding methods by…

Neurons and Cognition · Quantitative Biology 2023-12-14 Reese Kneeland , Jordyn Ojeda , Ghislain St-Yves , Thomas Naselaris

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Functional magnetic resonance imaging (fMRI) data is characterized by its complexity and high--dimensionality, encompassing signals from various regions of interests (ROIs) that exhibit intricate correlations. Analyzing fMRI data directly…

Applications · Statistics 2024-01-18 Yeseul Jeon , Jeong-Jae Kim , SuMin Yu , Junggu Choi , Sanghoon Han

While the standard network description of complex systems is based on quantifying links between pairs of system units, higher-order interactions (HOIs) involving three or more units play a major role in governing the collective network…

Brain structural networks are often represented as discrete adjacency matrices with elements summarizing the connectivity between pairs of regions of interest (ROIs). These ROIs are typically determined a-priori using a brain atlas. The…

Computation · Statistics 2023-08-11 William Consagra , Martin Cole , Xing Qiu , Zhengwu Zhang

Diverse cognitive processes set different demands on locally segregated and globally integrated brain activity. However, it remains unclear how resting brains configure their functional organization to balance the demands on network…

Neurons and Cognition · Quantitative Biology 2022-04-25 Rong Wang , Mianxin Liu , Xinhong Cheng , Ying Wu , Andrea Hildebrandt , Changsong Zhou

Functional brain network has been widely studied to understand the relationship between brain organization and behavior. In this paper, we aim to explore the functional connectivity of brain network under a \emph{multi-step} cognitive task…

Neurons and Cognition · Quantitative Biology 2017-12-06 Shi-Min Cai , Wei Chen , Dong-Bai Liu , Ming Tang , Xun Chen

Inter-subject registration of cortical areas is necessary in functional imaging (fMRI) studies for making inferences about equivalent brain function across a population. However, many high-level visual brain areas are defined as peaks of…

Neurons and Cognition · Quantitative Biology 2016-06-09 Marius Cătălin Iordan , Armand Joulin , Diane M. Beck , Li Fei-Fei

Mapping human brain activity to natural images offers a new window into vision and cognition, yet current diffusion-based decoders face a core difficulty: most condition directly on fMRI features without analyzing how visual information is…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Guowei Zhang , Yun Zhao , Moein Khajehnejad , Adeel Razi , Levin Kuhlmann

This work is an endeavor to develop a deep learning methodology for automated anatomical labeling of a given region of interest (ROI) in brain computed tomography (CT) scans. We combine both local and global context to obtain a…

Computer Vision and Pattern Recognition · Computer Science 2018-01-23 Srikrishna Varadarajan , Muktabh Mayank Srivastava , Monika Grewal , Pulkit Kumar

Accurately characterizing higher-order interactions of brain regions and extracting interpretable organizational patterns from Functional Magnetic Resonance Imaging data is crucial for brain disease diagnosis. Current graph-based deep…

Neurons and Cognition · Quantitative Biology 2026-03-16 Dengyi Zhao , Zhiheng Zhou , Guiying Yan , Dongxiao Yu , Xingqin Qi

Mammalian tissue architecture is central to biological function, and its disruption is a hallmark of disease. Medical imaging techniques can generate large point cloud datasets that capture changes in the cellular composition of such…

This article introduces a predictor-dependent joint modeling framework for network data obtained from multiple subjects over a shared set of nodes with spatial co-ordinates and spatially correlated nodal attributes. The framework is highly…

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