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In biomedical Subgroup Discovery, practitioners are interested in discovering interpretable and homogeneous subgroups within a group of patients. In this paper, assuming that healthy subjects (i.e., controls) share common but irrelevant…

Machine Learning · Computer Science 2026-05-21 Robin Louiset , Edouard Duchesnay , Benoit Dufumier , Antoine Grigis , Pietro Gori

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

Deep Learning has emerged as one of the most significant innovations in machine learning. However, a notable limitation of this field lies in the ``black box" decision-making processes, which have led to skepticism within groups like…

Machine Learning · Computer Science 2025-03-06 Shi Li

Robustness of embedded biometric systems is of prime importance with the emergence of fourth generation communication devices and advancement in security systems This paper presents the realization of such technologies which demands…

Computer Vision and Pattern Recognition · Computer Science 2012-04-06 Aamir Khan , Hasan Farooq

This article addresses extraction of physically meaningful information from STEM EELS and EDX spectrum-images using methods of Multivariate Statistical Analysis. The problem is interpreted in terms of data distribution in a…

Data Analysis, Statistics and Probability · Physics 2021-05-24 Pavel Potapov , Axel Lubk

The discovery of new materials is often constrained by the need for large labelled datasets or expensive simulations. In this study, we explore the use of Disentangling Autoencoders (DAEs) to learn compact and interpretable representations…

Materials Science · Physics 2025-07-29 Jaehoon Cha , Tingyao Lu , Matthew Walker , Keith T. Butler

Reliable classification and detection of certain medical conditions, in images, with state-of-the-art semantic segmentation networks, require vast amounts of pixel-wise annotation. However, the public availability of such datasets is…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Erik Ostrowski , Bharath Srinivas Prabakaran , Muhammad Shafique

We present a new technique called contrastive principal component analysis (cPCA) that is designed to discover low-dimensional structure that is unique to a dataset, or enriched in one dataset relative to other data. The technique is a…

Machine Learning · Statistics 2017-11-23 Abubakar Abid , Martin J. Zhang , Vivek K. Bagaria , James Zou

Deep learning has made significant strides in medical imaging, leveraging the use of large datasets to improve diagnostics and prognostics. However, large datasets often come with inherent errors through subject selection and acquisition.…

Autoencoders and generative models produce some of the most spectacular deep learning results to date. However, understanding and controlling the latent space of these models presents a considerable challenge. Drawing inspiration from…

Computer Vision and Pattern Recognition · Computer Science 2020-06-16 Chi-Hieu Pham , Saïd Ladjal , Alasdair Newson

As digital medical imaging becomes more prevalent and archives increase in size, representation learning exposes an interesting opportunity for enhanced medical decision support systems. On the other hand, medical imaging data is often…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Eduardo Pinho , Carlos Costa

Ensemble learning has had many successes in supervised learning, but it has been rare in unsupervised learning and dimensionality reduction. This study explores dimensionality reduction ensembles, using principal component analysis and…

Machine Learning · Statistics 2017-10-13 Colleen M. Farrelly

We introduce a new discriminant analysis method (Empirical Discriminant Analysis or EDA) for binary classification in machine learning. Given a dataset of feature vectors, this method defines an empirical feature map transforming the…

Machine Learning · Statistics 2012-10-30 Mark A. Kon , Nikolay Nikolaev

Since medical image data sets contain few samples and singular features, lesions are viewed as highly similar to other tissues. The traditional neural network has a limited ability to learn features. Even if a host of feature maps is…

Computer Vision and Pattern Recognition · Computer Science 2020-09-29 Hongfeng You , Long Yu , Shengwei Tian , Xiang Ma , Yan Xing , Xiaojie Ma

The differential diagnosis of neurodegenerative diseases, characterized by overlapping symptoms, may be challenging. Brain imaging coupled with artificial intelligence has been previously proposed for diagnostic support, but most of these…

Image and Video Processing · Electrical Eng. & Systems 2025-02-21 Pierrick Coupé , Boris Mansencal , José V. Manjón , Patrice Péran , Wassilios G. Meissner , Thomas Tourdias , Vincent Planche

Deep convolutional neural networks (DCNNs) have become the state-of-the-art computational models of biological object recognition. Their remarkable success has helped vision science break new ground and recent efforts have started to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Leonard E. van Dyck , Walter R. Gruber

We introduce principal differences analysis (PDA) for analyzing differences between high-dimensional distributions. The method operates by finding the projection that maximizes the Wasserstein divergence between the resulting univariate…

Machine Learning · Statistics 2017-05-03 Jonas Mueller , Tommi Jaakkola

In this work, we characterize the performance of a deep convolutional neural network designed to detect and quantify chemical elements in experimental X-ray photoelectron spectroscopy data. Given the lack of a reliable database in…

Disordered Systems and Neural Networks · Physics 2019-09-13 Giovanni Drera , Chahan M. Kropf , Luigi Sangaletti

Partial differential equations (PDEs) play a foundational role in modeling physical phenomena. This study addresses the challenging task of determining variable coefficients within PDEs from measurement data. We introduce a novel neural…

Numerical Analysis · Mathematics 2023-10-17 Ke Chen , Jasen Lai , Chunmei Wang

In the era of big data, there is an increasing need for healthcare providers, communities, and researchers to share data and collaborate to improve health outcomes, generate valuable insights, and advance research. The Health Insurance…

Cryptography and Security · Computer Science 2023-05-23 Kai Zhang , Xiaoqian Jiang