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We articulate the design imperatives for machine-learning based digital twins for nonlinear dynamical systems subject to external driving, which can be used to monitor the ``health'' of the target system and anticipate its future collapse.…

Adaptation and Self-Organizing Systems · Physics 2022-10-13 Ling-Wei Kong , Yang Weng , Bryan Glaz , Mulugeta Haile , Ying-Cheng Lai

Digital twins are transforming engineering and applied sciences by enabling real-time monitoring, simulation, and predictive analysis of physical systems and processes. However, conventional digital twins rely primarily on passive data…

Computational Engineering, Finance, and Science · Computer Science 2026-03-31 Matteo Torzoni , Domenico Maisto , Andrea Manzoni , Francesco Donnarumma , Giovanni Pezzulo , Alberto Corigliano

Smart Digital twins (SDTs) are being increasingly used to virtually replicate and predict the behaviors of complex physical systems through continual data assimilation enabling the optimization of the performance of these systems by…

Computer Vision and Pattern Recognition · Computer Science 2024-01-08 Md Ruman Islam , Mahadevan Subramaniam , Pei-Chi Huang

This article presents a vision where \textit{real-time} digital twins of the physical wireless environments are continuously updated using multi-modal sensing data from the distributed infrastructure and user devices, and are used to make…

Signal Processing · Electrical Eng. & Systems 2023-01-27 Ahmed Alkhateeb , Shuaifeng Jiang , Gouranga Charan

Digital twin (DT) technologies have emerged as a solution for real-time data-driven modeling of cyber physical systems (CPS) using the vast amount of data available by Internet of Things (IoT) networks. In this position paper, we elucidate…

Networking and Internet Architecture · Computer Science 2022-04-12 Jithin Jagannath , Keyvan Ramezanpour , Anu Jagannath

A digital twin is a surrogate model that has the main feature to mirror the original process behavior. Associating the dynamical process with a digital twin model of reduced complexity has the significant advantage to map the dynamics with…

Numerical Analysis · Mathematics 2024-03-19 Diana Alina Bistrian , Omer San , Ionel Michael Navon

Central to the digital transformation of the process industry are Digital Twins (DTs), virtual replicas of physical manufacturing systems that combine sensor data with sophisticated data-based or physics-based models, or a combination…

Machine Learning · Computer Science 2024-07-03 Michael Mayr , Georgios C. Chasparis , Josef Küng

Convolutional Neural Networks (CNNs) constitute a class of Deep Learning models which have been used in the recent past to resolve many problems in computer vision, in particular optical flow estimation. Measuring displacement and strain…

Image and Video Processing · Electrical Eng. & Systems 2020-09-10 S. Boukhtache , K. Abdelouahab , F. Berry , B. Blaysat , M. Grediac , F. Sur

Recent technological advances have expanded the availability of high-throughput biological datasets, enabling the reliable design of digital twins of biomedical systems or patients. Such computational tools represent key reaction networks…

Quantitative Methods · Quantitative Biology 2025-09-03 Clémence Métayer , Annabelle Ballesta , Julien Martinelli

Micro-Electro-Mechanical-Systems are complex structures, often involving nonlinearites of geometric and multiphysics nature, that are used as sensors and actuators in countless applications. Starting from full-order representations, we…

Dynamical Systems · Mathematics 2023-04-04 Giorgio Gobat , Stefania Fresca , Andrea Manzoni , Attilio Frangi

Purpose: Digital twins are virtual interactive models of the real world, exhibiting identical behavior and properties. In surgical applications, computational analysis from digital twins can be used, for example, to enhance situational…

The science of solving clinical problems by analyzing images generated in clinical practice is known as medical image analysis. The aim is to extract information in an effective and efficient manner for improved clinical diagnosis. The…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Syed Muhammad Anwar , Muhammad Majid , Adnan Qayyum , Muhammad Awais , Majdi Alnowami , Muhammad Khurram Khan

Effective real-time monitoring is a foundation of digital twin technology, crucial for detecting material degradation and maintaining the structural integrity of nuclear systems to ensure both safety and operational efficiency. Traditional…

Machine Learning · Computer Science 2024-12-02 Raisa Bentay Hossain , Farid Ahmed , Kazuma Kobayashi , Seid Koric , Diab Abueidda , Syed Bahauddin Alam

We introduce a novel digital twin framework for predictive maintenance of long-term physical systems. Using monitoring tire health as an application, we show how the digital twin framework can be used to enhance automotive safety and…

Machine Learning · Computer Science 2024-08-13 Vispi Karkaria , Jie Chen , Christopher Luey , Chase Siuta , Damien Lim , Robert Radulescu , Wei Chen

Medical imaging has played a pivotal role in advancing and refining digital twin technology, allowing for the development of highly personalized virtual models that represent human anatomy and physiological functions. A key component in…

Medical Physics · Physics 2024-11-14 Feng Zhao , Yizhou Wu , Mingzhe Hu , Chih-Wei Chang , Ruirui Liu , Richard Qiu , Xiaofeng Yang

A digital twin is a virtual replica of a real-world physical phenomena that uses mathematical modeling to characterize and simulate its defining features. By constructing digital twins for disease processes, we can perform in-silico…

Machine Learning · Computer Science 2024-11-04 Keying Kuang , Frances Dean , Jack B. Jedlicki , David Ouyang , Anthony Philippakis , David Sontag , Ahmed M. Alaa

Human digital twins (HDTs) are dynamic, data-driven virtual representations of individuals, continuously updated with multimodal data to simulate, monitor, and predict health trajectories. By integrating clinical, physiological, behavioral,…

Human-Computer Interaction · Computer Science 2025-08-19 Rong Pan , Hongyue Sun , Xiaoyu Chen , Giulia Pedrielli , Jiapeng Huang

Emerging from NASA's spacecraft simulations in the 1960s, digital twin technology has advanced through industrial adoption to spark a healthcare transformation. A digital twin is a dynamic, data-driven virtual counterpart of a physical…

Artificial Intelligence · Computer Science 2025-11-27 Yunqi Zhang , Kuangyu Shi , Biao Li

Digital Twins (DTs) are virtual representations of physical systems synchronized in real time through Internet of Things (IoT) sensors and computational models. In industrial applications, DTs enable predictive maintenance, fault diagnosis,…

Other Computer Science · Computer Science 2025-07-18 Ali Mohammad-Djafari

Digital twin (DT) enables smart manufacturing by leveraging real-time data, AI models, and intelligent control systems. This paper presents a state-of-the-art analysis on the emerging field of DTs in the context of milling. The critical…

Systems and Control · Electrical Eng. & Systems 2025-12-16 Wenyi Liu , R. Sharma , W. "Grace" Guo , J. Yi , Y. B. Guo
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