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Gigapixel medical images provide massive data, both morphological textures and spatial information, to be mined. Due to the large data scale in histology, deep learning methods play an increasingly significant role as feature extractors.…

Image and Video Processing · Electrical Eng. & Systems 2022-06-16 Yiqing Shen , Bingxin Zhou , Xinye Xiong , Ruitian Gao , Yu Guang Wang

Advancements in technologies related to working with omics data require novel computation methods to fully leverage information and help develop a better understanding of human diseases. This paper studies the effects of introducing graph…

Genomics · Quantitative Biology 2023-10-17 Nishant Rajadhyaksha , Aarushi Chitkara

Graph neural network (GNN) models are increasingly being used for the classification of electroencephalography (EEG) data. However, GNN-based diagnosis of neurological disorders, such as Alzheimer's disease (AD), remains a relatively…

Neurons and Cognition · Quantitative Biology 2023-12-21 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Multi-modal brain tumor segmentation remains challenging for practical deployment due to the high computational costs of mainstream models. In this work, we propose GMLN-BTS, a Graph-based Multi-modal interaction Lightweight Network for…

Image and Video Processing · Electrical Eng. & Systems 2026-03-06 Guohao Huo , Ruiting Dai , Zitong Wang , Junxin Kong , Hao Tang

Heterogeneous graph neural networks aim to discover discriminative node embeddings and relations from multi-relational networks.One challenge of heterogeneous graph learning is the design of learnable meta-paths, which significantly…

Machine Learning · Computer Science 2023-04-19 Zhaoliang Chen , Zhihao Wu , Luying Zhong , Claudia Plant , Shiping Wang , Wenzhong Guo

Aiming at the limitations of traditional medical decision system in processing large-scale heterogeneous medical data and realizing highly personalized recommendation, this paper introduces a personalized medical decision algorithm…

Machine Learning · Computer Science 2024-05-29 Yafeng Yan , Shuyao He , Zhou Yu , Jiajie Yuan , Ziang Liu , Yan Chen

Graph-based neural network models are gaining traction in the field of representation learning due to their ability to uncover latent topological relationships between entities that are otherwise challenging to identify. These models have…

Image and Video Processing · Electrical Eng. & Systems 2023-07-25 Aryan Singh , Pepijn Van de Ven , Ciarán Eising , Patrick Denny

Clustering cancer patients into subgroups and identifying cancer subtypes is an important task in cancer genomics. Clustering based on comprehensive multi-omic molecular profiling can often achieve better results than those using a single…

Genomics · Quantitative Biology 2017-08-25 Tianle Ma , Aidong Zhang

The increasing quantity of multi-omics data, such as methylomic and transcriptomic profiles, collected on the same specimen, or even on the same cell, provide a unique opportunity to explore the complex interactions that define cell…

In this paper, we propose MGNet, a simple and effective multiplex graph convolutional network (GCN) model for multimodal brain network analysis. The proposed method integrates tensor representation into the multiplex GCN model to extract…

Computer Vision and Pattern Recognition · Computer Science 2021-08-03 Zhaoming Kong , Lichao Sun , Hao Peng , Liang Zhan , Yong Chen , Lifang He

There exists unexplained diverse variation within the predefined colon cancer stages using only features either from genomics or histopathological whole slide images as prognostic factors. Unraveling this variation will bring about improved…

Quantitative Methods · Quantitative Biology 2022-12-15 Olalekan Ogundipe , Zeyneb Kurt , Wai Lok Woo

ASD is a complicated neurodevelopmental disorder marked by variation in symptom presentation and neurological underpinnings, making early and objective diagnosis extremely problematic. This paper presents a Graph Convolutional Network (GCN)…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Adnan Ferdous Ashrafi , Hasanul Kabir

Current graph clustering methods emphasize individual node and edge con nections, while ignoring higher-order organization at the level of motif. Re cently, higher-order graph clustering approaches have been designed by motif based…

Machine Learning · Computer Science 2024-05-21 Ye Liu , Xuelei Lin , Yejia Chen , Reynold Cheng

Multi-label classification aims to recognize multiple objects or attributes from images. However, it is challenging to learn from proper label graphs to effectively characterize such inter-label correlations or dependencies. Current methods…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Jin Yuan , Shikai Chen , Yao Zhang , Zhongchao Shi , Xin Geng , Jianping Fan , Yong Rui

The potential benefits of applying machine learning methods to -omics data are becoming increasingly apparent, especially in clinical settings. However, the unique characteristics of these data are not always well suited to machine learning…

Breast cancer is one of the most common cancers in women worldwide, and early detection can significantly reduce the mortality rate of breast cancer. It is crucial to take multi-scale information of tissue structure into account in the…

Computer Vision and Pattern Recognition · Computer Science 2021-01-01 Mo Zhang , Quanzheng Li

Accurate classification of breast cancer histopathology images is pivotal for early oncological diagnosis and therapeutic intervention.However, conventional deep learning architectures often encounter performance degradation under limited…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Lin-Guo Gao , Suxing Liu

Swift and accurate blood smear analysis is an effective diagnostic method for leukemia and other hematological malignancies. However, manual leukocyte count and morphological evaluation using a microscope is time-consuming and prone to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Chandravardhan Singh Raghaw , Arnav Sharma , Shubhi Bansal , Mohammad Zia Ur Rehman , Nagendra Kumar

Being low-level radiation exposure and less harmful to health, low-dose computed tomography (LDCT) has been widely adopted in the early screening of lung cancer and COVID-19. LDCT images inevitably suffer from the degradation problem caused…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Kecheng Chen , Jiayu Sun , Jiang Shen , Jixiang Luo , Xinyu Zhang , Xuelin Pan , Dongsheng Wu , Yue Zhao , Miguel Bento , Yazhou Ren , Xiaorong Pu

In the relentless efforts in enhancing medical diagnostics, the integration of state-of-the-art machine learning methodologies has emerged as a promising research area. In molecular biology, there has been an explosion of data generated…

Machine Learning · Computer Science 2024-05-17 Ibrahim Al-Hurani , Abedalrhman Alkhateeb , Salama Ikki