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The adaptive immune system is a dynamical, self-organized multiscale system that protects vertebrates from both pathogens and internal irregularities, such as tumours. For these reason it fascinates physicists, yet the multitude of…

Quantitative Methods · Quantitative Biology 2020-11-20 Grégoire Altan-Bonnet , Thierry Mora , Aleksandra M. Walczak

Biological systems have evolved to amazingly complex states, yet we do not understand in general how evolution operates to generate increasing genetic and functional complexity. Molecular recognition sites are short genome segments or…

Populations and Evolution · Quantitative Biology 2025-01-06 Tom Röschinger , Roberto Morán Tovar , Simone Pompei , Michael Lässig

In numerous contexts, individuals may decide whether they take actions to mitigate the spread of disease, or not. Mitigating the spread of disease requires an individual to change their routine behaviours to benefit others, resulting in a…

Physics and Society · Physics 2020-08-11 Julie Rowlett , Carl-Joar Karlsson

The adaptive immune system is a natural diagnostic and therapeutic. It recognizes threats earlier than clinical symptoms manifest and neutralizes antigen with exquisite specificity. Recognition specificity and broad reactivity is enabled…

Quantitative Methods · Quantitative Biology 2019-07-26 Alex J. Brown , Igor Snapkov , Rahmad Akbar , Milena Pavlović , Enkelejda Miho , Geir K. Sandve , Victor Greiff

For over a century, immunology has masterfully discovered and dissected the components of our immune system, yet its collective behavior remains fundamentally unpredictable. In this perspective, we argue that building on the learnings of…

The coming 5G networks have been enabling the creation of a wide variety of new services and applications which demand a new network security architecture. Immunology is the study of the immune system in vertebrates (including humans) which…

Cryptography and Security · Computer Science 2020-01-28 Quan Yu , Jing Ren , Jiyan Zhang , Siyang Liu , Yinjin Fu , Ying Li , Linru Ma , Jian Jing , Wei Zhang

Viruses display striking diversity in structure, transmission mode, immune interaction, and evolutionary behavior. Despite this diversity, viral strategies are not unconstrained. Here we present a unifying framework that treats viral…

Biological Physics · Physics 2025-12-30 Mohammad Rasoolinejad

Viruses like influenza have long coevolved with host immune systems, gradually shaping the evolutionary trajectory of these pathogens. Host immune systems develop immunity against circulating strains, which in turn avoid extinction by…

We consider a simple information-theoretic model of communication, in which two species of bacteria have the option of exchanging information about their environment, thereby improving their chances of survival. For this purpose, we model a…

Multiagent Systems · Computer Science 2016-04-05 Andres C. Burgos , Daniel Polani

Explaining how competing species coexist remains a central question in ecology. The well-known competitive exclusion principle (CEP) states that two species competing for the same resource cannot stably coexist, and more generally, that the…

Biological Physics · Physics 2026-01-01 Wei Tao , Ju Kang , Wenxiu Yang , Yiyuan Niu , Xin Wang

Body size or mass is one of the main factors underlying food webs structure. A large number of evolutionary models have shown that indeed, the adaptive evolution of body size (or mass) can give rise to hierarchically organised trophic…

Populations and Evolution · Quantitative Biology 2021-08-27 Coralie Fritsch , Sylvain Billiard , Nicolas Champagnat

Emerging empirical and theoretical thinking about human aging places considerable value upon the role of the environment as a major factor which can promote prolonged healthy longevity. Our contemporary, information-rich environment is…

Other Quantitative Biology · Quantitative Biology 2014-07-24 Marios Kyriazis

We model the immune surveillance of a pathogen which passes through $n$ immunologically distinct stages. The biological parameters of this system induce a partial order on the stages, and this, in turn, determines which stages will be…

Populations and Evolution · Quantitative Biology 2010-05-04 Edgar Delgado-Eckert , Michael Shapiro

We study the adaptive dynamics of predator-prey systems modeled by a dynamical system in which the traits of predators and prey are allowed to evolve by small mutations. When only the prey are allowed to evolve, and the size of the…

Probability · Mathematics 2015-03-13 Rick Durrett , John Mayberry

We integrate dual-process theories of human cognition with evolutionary game theory to study the evolution of automatic and controlled decision-making processes. We introduce a model where agents who make decisions using either automatic or…

Dynamical Systems · Mathematics 2015-07-07 Danielle F. P. Toupo , Steven H. Strogatz , Jonathan D. Cohen , David G. Rand

Many illnesses are associated with an alteration of the immune system homeostasis due to any combination of factors, including exogenous bacterial insult, endogenous breakdown (e.g., development of a disease that results in immuno…

Biological Physics · Physics 2009-06-08 D. Sornette , V. I. Yukalov , E. P. Yukalova , J. -Y. Henry , D. Schwab , J. P. Cobb

Human societies around the world interact with each other by developing and maintaining social norms, and it is critically important to understand how such norms emerge and change. In this work, we define an evolutionary game-theoretic…

Computers and Society · Computer Science 2017-04-18 Soham De , Dana S. Nau , Michele J. Gelfand

Biological organisms are open, adaptve systems that can respond to changes in environment in specific ways. Adaptation and response can be posed as an optimization problem, with a tradeoff between the benefit obtained from a response and…

Statistical Mechanics · Physics 2018-10-17 Suman G. Das , Madan Rao , Garud Iyengar

Understanding the evolution of human social systems requires flexible formalisms for the emergence of institutions. Although game theory is normally used to model interactions individually, larger spaces of games can be helpful for modeling…

Physics and Society · Physics 2021-08-12 Seth Frey , Curtis Atkisson

In real-life complex systems, individuals often encounter multiple social dilemmas that cannot be effectively captured using a single-game model. Furthermore, the environment and limited resources both play a crucial role in shaping…

Physics and Society · Physics 2025-04-15 Chengbin Sun , Alfonso de Miguel-Arribas , Chaoqian Wang , Haoxiang Xia , Yamir Moreno
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