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Biomedical datasets are often modeled as knowledge graphs (KGs) because they capture the multi-relational, heterogeneous, and dynamic natures of biomedical systems. KG completion (KGC), can, therefore, help researchers make predictions to…

Artificial Intelligence · Computer Science 2023-07-18 Lauren Nicole DeLong , Ramon Fernández Mir , Zonglin Ji , Fiona Niamh Coulter Smith , Jacques D. Fleuriot

Large Language Models (LLMs) have achieved significant success in open-domain question answering. However, they continue to face challenges such as hallucinations and knowledge cutoffs. These issues can be mitigated through in-context…

Computation and Language · Computer Science 2025-02-19 Zukang Yang , Zixuan Zhu , Xuan Zhu

Question Answering (QA) in clinical notes has gained a lot of attention in the past few years. Existing machine reading comprehension approaches in clinical domain can only handle questions about a single block of clinical texts and fail to…

Computation and Language · Computer Science 2022-07-25 Ping Wang , Tian Shi , Khushbu Agarwal , Sutanay Choudhury , Chandan K. Reddy

Graph Retrieval-Augmented Generation (Graph RAG) effectively builds a knowledge graph (KG) to connect disparate facts across a large document corpus. However, this broad-view approach often lacks the deep structured reasoning needed for…

Computation and Language · Computer Science 2025-10-27 Jiaoyang Li , Junhao Ruan , Shengwei Tang , Saihan Chen , Kaiyan Chang , Yuan Ge , Tong Xiao , Jingbo Zhu

This paper presents RAG-KG-IL, a novel multi-agent hybrid framework designed to enhance the reasoning capabilities of Large Language Models (LLMs) by integrating Retrieval-Augmented Generation (RAG) and Knowledge Graphs (KGs) with an…

Computation and Language · Computer Science 2025-03-19 Hong Qing Yu , Frank McQuade

Evaluating large language models (LLMs) has recently emerged as a critical issue for safe and trustworthy application of LLMs in the medical domain. Although a variety of static medical question-answering (QA) benchmarks have been proposed,…

Computation and Language · Computer Science 2025-12-12 Gyutaek Oh , Sangjoon Park , Byung-Hoon Kim

Knowledge graphs (KGs) serve as powerful tools for organizing and representing structured knowledge. While their utility is widely recognized, challenges persist in their automation and completeness. Despite efforts in automation and the…

Artificial Intelligence · Computer Science 2024-05-07 Mutahira Khalid , Raihana Rahman , Asim Abbas , Sushama Kumari , Iram Wajahat , Syed Ahmad Chan Bukhari

Large Language Models (LLMs) excel at many reasoning tasks but struggle with knowledge-intensive queries due to their inability to dynamically access up-to-date or domain-specific information. Retrieval-Augmented Generation (RAG) has…

Computation and Language · Computer Science 2026-03-03 Minghao Guo , Qingcheng Zeng , Xujiang Zhao , Yanchi Liu , Wenchao Yu , Mengnan Du , Haifeng Chen , Wei Cheng

With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…

Artificial Intelligence · Computer Science 2025-12-29 Zelin Zang , Wenyi Gu , Siqi Ma , Dan Yang , Yue Shen , Zhu Zhang , Guohui Fan , Wing-Kuen Ling , Fuji Yang

Visual Question Answering (VQA) is a novel problem domain where multi-modal inputs must be processed in order to solve the task given in the form of a natural language. As the solutions inherently require to combine visual and natural…

Computer Vision and Pattern Recognition · Computer Science 2018-01-31 Mikyas T. Desta , Larry Chen , Tomasz Kornuta

Recent advances in large language models (LLMs) have led to impressive progress in natural language generation, yet their tendency to produce hallucinated or unsubstantiated content remains a critical concern. To improve factual…

Computation and Language · Computer Science 2025-05-20 Xukai Liu , Ye Liu , Shiwen Wu , Yanghai Zhang , Yihao Yuan , Kai Zhang , Qi Liu

Understanding complex biomolecular mechanisms requires multi-step reasoning across molecular interactions, signaling cascades, and metabolic pathways. While large language models(LLMs) show promise in such tasks, their application to…

Artificial Intelligence · Computer Science 2025-11-12 Tianwen Lyu , Xiang Zhuang , Keyan Ding , Xinzhe Cao , Lei Liang , Wei Zhao , Qiang Zhang , Huajun Chen

Automated question-answering (QA) systems increasingly rely on retrieval-augmented generation (RAG) to ground large language models (LLMs) in authoritative medical knowledge, ensuring clinical accuracy and patient safety in Artificial…

Computation and Language · Computer Science 2026-03-05 Aswini Sivakumar , Vijayan Sugumaran , Yao Qiang

The Knowledge Graph Completion~(KGC) task aims to infer the missing entity from an incomplete triple. Existing embedding-based methods rely solely on triples in the KG, which is vulnerable to specious relation patterns and long-tail…

Artificial Intelligence · Computer Science 2025-05-01 Muzhi Li , Cehao Yang , Chengjin Xu , Xuhui Jiang , Yiyan Qi , Jian Guo , Ho-fung Leung , Irwin King

Automated question answering (QA) over electronic health records (EHRs) can bridge critical information gaps for clinicians and patients, yet it demands both precise evidence retrieval and faithful answer generation under limited…

Retrieval-Augmented Generation (RAG) enables large language models (LLMs) to access external knowledge sources, but the effectiveness of RAG relies on the coordination between the retriever and the generator. Since these components are…

Computation and Language · Computer Science 2025-09-24 Junlin Wang , Zehao Wu , Shaowei Lu , Yanlan Li , Xinghao Huang

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

Retrieval-augmented generation (RAG) enables large language models (LLMs) to dynamically access external information, which is powerful for answering questions over previously unseen documents. Nonetheless, they struggle with high-level…

Artificial Intelligence · Computer Science 2026-04-21 Chi-Hsiang Hsiao , Yi-Cheng Wang , Tzung-Sheng Lin , Yi-Ren Yeh , Chu-Song Chen

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

Supporting learners' understanding of taught skills in online settings is a longstanding challenge. While exercises and chat-based agents can evaluate understanding in limited contexts, this challenge is magnified when learners seek…

Artificial Intelligence · Computer Science 2025-04-11 Rahul K. Dass , Rochan H. Madhusudhana , Erin C. Deye , Shashank Verma , Timothy A. Bydlon , Grace Brazil , Ashok K. Goel