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Pursuing artificial intelligence for biomedical science, a.k.a. AI Scientist, draws increasing attention, where one common approach is to build a copilot agent driven by Large Language Models (LLMs). However, to evaluate such systems,…

Computation and Language · Computer Science 2024-07-02 Xinna Lin , Siqi Ma , Junjie Shan , Xiaojing Zhang , Shell Xu Hu , Tiannan Guo , Stan Z. Li , Kaicheng Yu

In the realm of multimodal tasks, Visual Question Answering (VQA) plays a crucial role by addressing natural language questions grounded in visual content. Knowledge-Based Visual Question Answering (KBVQA) advances this concept by adding…

Computation and Language · Computer Science 2024-06-17 Manas Jhalani , Annervaz K M , Pushpak Bhattacharyya

Biomedical knowledge graphs (KG) are heterogenous networks consisting of biological entities as nodes and relations between them as edges. These entities and relations are extracted from millions of research papers and unified in a single…

Artificial Intelligence · Computer Science 2022-11-11 Dattaraj J. Rao , Shraddha S. Mane , Mukta A. Paliwal

The rapid expansion of medical literature presents growing challenges for structuring and integrating domain knowledge at scale. Knowledge Graphs (KGs) offer a promising solution by enabling efficient retrieval, automated reasoning, and…

Computation and Language · Computer Science 2025-08-20 Duzhen Zhang , Zixiao Wang , Zhong-Zhi Li , Yahan Yu , Shuncheng Jia , Jiahua Dong , Haotian Xu , Xing Wu , Yingying Zhang , Tielin Zhang , Jie Yang , Xiuying Chen , Le Song

Medical tasks such as diagnosis and treatment planning require precise and complex reasoning, particularly in life-critical domains. Unlike mathematical reasoning, medical reasoning demands meticulous, verifiable thought processes to ensure…

Computation and Language · Computer Science 2025-04-08 Juncheng Wu , Wenlong Deng , Xingxuan Li , Sheng Liu , Taomian Mi , Yifan Peng , Ziyang Xu , Yi Liu , Hyunjin Cho , Chang-In Choi , Yihan Cao , Hui Ren , Xiang Li , Xiaoxiao Li , Yuyin Zhou

Open-domain Knowledge Graph Completion (KGC) faces significant challenges in an ever-changing world, especially when considering the continual emergence of new entities in daily news. Existing approaches for KGC mainly rely on pretrained…

Artificial Intelligence · Computer Science 2025-08-07 Ruochen Zhao , Simone Conia , Eric Peng , Min Li , Saloni Potdar

Knowledge Graph Question Answering (KGQA) involves retrieving entities as answers from a Knowledge Graph (KG) using natural language queries. The challenge is to learn to reason over question-relevant KG facts that traverse KG entities and…

Computation and Language · Computer Science 2022-10-26 Costas Mavromatis , George Karypis

Knowledge-Based Visual Question Answering (KBVQA) is a bi-modal task requiring external world knowledge in order to correctly answer a text question and associated image. Recent single modality text work has shown knowledge injection into…

Computation and Language · Computer Science 2022-05-30 Diego Garcia-Olano , Yasumasa Onoe , Joydeep Ghosh

Dermatological care via telemedicine often lacks the rich context of in-person visits. Clinicians must make diagnoses based on a handful of images and brief descriptions, without the benefit of physical exams, second opinions, or reference…

Artificial Intelligence · Computer Science 2025-08-27 Karishma Thakrar , Shreyas Basavatia , Akshay Daftardar

Biomedical knowledge graphs (KGs) encode vast, heterogeneous information spanning literature, genes, pathways, drugs, diseases, and clinical trials, but leveraging them collectively for scientific discovery remains difficult. Their…

Information Retrieval · Computer Science 2026-01-21 Zifeng Wang , Zheng Chen , Ziwei Yang , Xuan Wang , Qiao Jin , Yifan Peng , Zhiyong Lu , Jimeng Sun

Large language models (LLMs) achieve strong results on knowledge graph question answering (KGQA), but most benchmarks assume complete knowledge graphs (KGs) where direct supporting triples exist. This reduces evaluation to shallow retrieval…

Artificial Intelligence · Computer Science 2025-12-18 Dongzhuoran Zhou , Yuqicheng Zhu , Xiaxia Wang , Hongkuan Zhou , Jiaoyan Chen , Steffen Staab , Yuan He , Evgeny Kharlamov

Large Language Models~(LLMs) have demonstrated capabilities across various applications but face challenges such as hallucination, limited reasoning abilities, and factual inconsistencies, especially when tackling complex, domain-specific…

The reliable evaluation of large language models (LLMs) in medical applications remains an open challenge, particularly in capturing the complexity of multi-turn doctor-patient interactions that unfold in real clinical environments.…

Artificial Intelligence · Computer Science 2025-10-15 Yuechun Yu , Han Ying , Haoan Jin , Wenjian Jiang , Dong Xian , Binghao Wang , Zhou Yang , Mengyue Wu

Knowledge-based visual question answering (KB-VQA) requires vision-language models to understand images and use external knowledge, especially for rare entities and long-tail facts. Most existing retrieval-augmented generation (RAG) methods…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Zhuohong Chen , Zhenxian Wu , Yunyao Yu , Hangrui Xu , Zirui Liao , Zhifang Liu , Xiangwen Deng , Pen Jiao , Haoqian Wang

Medical question answer (QA) assistants respond to lay users' health-related queries by synthesizing information from multiple sources using natural language processing and related techniques. They can serve as vital tools to alleviate…

Computation and Language · Computer Science 2024-10-01 Prakash Chandra Sukhwal , Vaibhav Rajan , Atreyi Kankanhalli

In this paper, we aim to improve the reasoning ability of large language models (LLMs) over knowledge graphs (KGs) to answer complex questions. Inspired by existing methods that design the interaction strategy between LLMs and KG, we…

Computation and Language · Computer Science 2024-02-20 Jinhao Jiang , Kun Zhou , Wayne Xin Zhao , Yang Song , Chen Zhu , Hengshu Zhu , Ji-Rong Wen

Existing medical RAG systems mainly leverage knowledge from medical knowledge bases, neglecting the crucial role of experiential knowledge derived from similar patient cases -- a key component of human clinical reasoning. To bridge this…

Computation and Language · Computer Science 2025-05-27 Yuxing Lu , Gecheng Fu , Wei Wu , Xukai Zhao , Sin Yee Goi , Jinzhuo Wang

Iterative retrieval-augmented generation (iRAG) models offer an effective approach for multi-hop question answering (QA). However, their retrieval process faces two key challenges: (1) it can be disrupted by irrelevant documents or…

Computation and Language · Computer Science 2025-02-26 Jinyuan Fang , Zaiqiao Meng , Craig Macdonald

Search agents are language models (LMs) that reason and search knowledge bases (or the web) to answer questions; recent methods supervise only the final answer accuracy using reinforcement learning with verifiable rewards (RLVR). Most RLVR…

Machine Learning · Computer Science 2026-01-27 James Burgess , Jan N. Hansen , Duo Peng , Yuhui Zhang , Alejandro Lozano , Min Woo Sun , Emma Lundberg , Serena Yeung-Levy

Unlocking deep and interpretable biological reasoning from complex genomic data remains a major AI challenge limiting scientific progress. While current DNA foundation models excel at representing sequences, they struggle with multi-step…

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