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Score-based generative modeling, informally referred to as diffusion models, continue to grow in popularity across several important domains and tasks. While they provide high-quality and diverse samples from empirical distributions,…

Machine Learning · Statistics 2023-12-29 Jacopo Teneggi , Matthew Tivnan , J. Webster Stayman , Jeremias Sulam

Uncertainty estimates of modern neuronal networks provide additional information next to the computed predictions and are thus expected to improve the understanding of the underlying model. Reliable uncertainties are particularly…

Computer Vision and Pattern Recognition · Computer Science 2018-06-11 Alain Jungo , Raphael Meier , Ekin Ermis , Evelyn Herrmann , Mauricio Reyes

Conformal prediction has recently emerged as a promising strategy for quantifying the uncertainty of a predictive model; these algorithms modify the model to output sets of labels that are guaranteed to contain the true label with high…

Machine Learning · Computer Science 2025-03-11 Botong Zhang , Shuo Li , Osbert Bastani

Conformal prediction is a simple and powerful tool that can quantify uncertainty without any distributional assumptions. Many existing methods only address the average coverage guarantee, which is not ideal compared to the stronger…

Machine Learning · Statistics 2023-02-21 Xing Han , Ziyang Tang , Joydeep Ghosh , Qiang Liu

Machine learning (ML) is transforming healthcare, but safe clinical decisions demand reliable uncertainty estimates that standard ML models fail to provide. Conformal prediction (CP) is a popular tool that allows users to turn heuristic…

Machine Learning · Computer Science 2025-12-18 Klaus-Rudolf Kladny , Bernhard Schölkopf , Lisa Koch , Christian F. Baumgartner , Michael Muehlebach

Neural network prediction probabilities and accuracy are often only weakly-correlated. Inherent label ambiguity in training data for image segmentation aggravates such miscalibration. We show that logit consistency across stochastic…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Neerav Karani , Neel Dey , Polina Golland

With model trustworthiness being crucial for sensitive real-world applications, practitioners are putting more and more focus on improving the uncertainty calibration of deep neural networks. Calibration errors are designed to quantify the…

Machine Learning · Computer Science 2024-03-14 Sebastian G. Gruber , Florian Buettner

Polyp segmentation is a crucial step towards computer-aided diagnosis of colorectal cancer. However, most of the polyp segmentation methods require pixel-wise annotated datasets. Annotated datasets are tedious and time-consuming to produce,…

Computer Vision and Pattern Recognition · Computer Science 2022-11-23 Guangyu Ren , Michalis Lazarou , Jing Yuan , Tania Stathaki

Deep learning models (DLMs) can achieve state-of-the-art performance in histopathology image segmentation and classification, but have limited deployment potential in real-world clinical settings. Uncertainty estimates of DLMs can increase…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Audrey Xie , Elhoucine Elfatimi , Sambuddha Ghosal , Pratik Shah

The deployment of Machine Learning models intraoperatively for tissue characterisation can assist decision making and guide safe tumour resections. For image classification models, pixel attribution methods are popular to infer…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Alfie Roddan , Chi Xu , Serine Ajlouni , Irini Kakaletri , Patra Charalampaki , Stamatia Giannarou

Deep learning has played a major role in the interpretation of dermoscopic images for detecting skin defects and abnormalities. However, current deep learning solutions for dermatological lesion analysis are typically limited in providing…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Gun-Hee Lee , Han-Bin Ko , Seong-Whan Lee

The reliable deployment of deep learning in medical imaging requires uncertainty quantification that provides rigorous error guarantees while remaining anatomically meaningful. Conformal prediction (CP) is a powerful distribution-free…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Mélanie Gaillochet , Christian Desrosiers , Hervé Lombaert

Conformal inference provides a rigorous statistical framework for uncertainty quantification in machine learning, enabling well-calibrated prediction sets with precise coverage guarantees for any classification model. However, its reliance…

With the advancement of Internet of Things (IoT) technologies, high-precision indoor positioning has become essential for Location-Based Services (LBS) in complex indoor environments. Fingerprint-based localization is popular, but…

Machine Learning · Computer Science 2025-05-06 Zhiyi Zhou , Hexin Peng , Hongyu Long

The use of mathematical models to make predictions about tumor growth and response to treatment has become increasingly more prevalent in the clinical setting. The level of complexity within these models ranges broadly, and the calibration…

Quantitative Methods · Quantitative Biology 2021-12-28 Allison L. Lewis , Kathleen M. Storey , Heyrim Cho , Anna C. Zittle

Deep learning motivated by convolutional neural networks has been highly successful in a range of medical imaging problems like image classification, image segmentation, image synthesis etc. However for validation and interpretability, not…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Abhinav Sagar

Uncertainty in medical image segmentation is inherently non-uniform, with boundary regions exhibiting substantially higher ambiguity than interior areas. Conventional training treats all pixels equally, leading to unstable optimization…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Jinming Zhang , Youpeng Yang , Xi Yang , Haosen Shi , Yuyao Yan , Qiufeng Wang , Guangliang Cheng , Kaizhu Huang

Uncertainty is critical to reliable decision-making with machine learning. Conformal prediction (CP) handles uncertainty by predicting a set on a test input, hoping the set to cover the true label with at least $(1-\alpha)$ confidence. This…

Machine Learning · Computer Science 2024-03-25 Rui Xu , Yue Sun , Chao Chen , Parv Venkitasubramaniam , Sihong Xie

In scientific disciplines such as neuroimaging, climatology, and cosmology it is useful to study the uncertainty of excursion sets of imaging data. While the case of imaging data obtained from a single study condition has already been…

Statistics Theory · Mathematics 2025-11-12 Thomas J. Maullin-Sapey , Fabian J. E. Telschow

Medical image segmentation is a fundamental and critical step in many clinical approaches. Semi-supervised learning has been widely applied to medical image segmentation tasks since it alleviates the heavy burden of acquiring…

Image and Video Processing · Electrical Eng. & Systems 2022-08-29 Yichi Zhang , Rushi Jiao , Qingcheng Liao , Dongyang Li , Jicong Zhang
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