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Objectives: The role of advanced diffusion-weighted imaging (DWI) in chronic liver disease (CLD) has not been fully studied. Chronic liver disease (CLD) is a progressive deterioration of liver functions, caused by one or more etiology. This…

Tissues and Organs · Quantitative Biology 2025-09-10 Jiqing Huang , Benjamin Leporq , Valérie Hervieu , Sophie Gaillard , Jerome Dumortier , Olivier Beuf , Hélène Ratiney

Liver fibrosis represents the accumulation of excessive extracellular matrix caused by sustained hepatic injury. It disrupts normal lobular architecture and function, increasing the chances of cirrhosis and liver failure. Precise staging of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-01 Yang Zhou , Kunhao Yuan , Ye Wei , Jishizhan Chen

We present an end-to-end deep learning framework for automated liver cirrhosis stage estimation from multi-sequence MRI. Cirrhosis is the severe scarring (fibrosis) of the liver and a common endpoint of various chronic liver diseases. Early…

Liver cirrhosis is an insidious condition involving the substitution of normal liver tissue with fibrous scar tissue and causing major health complications. The conventional method of diagnosis using liver biopsy is invasive and, therefore,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Kapil Kashyap , Sean Fargose , Chrisil Dabre , Fatema Dolaria , Nilesh Patil , Aniket Kore

Liver cirrhosis represents the end stage of chronic liver disease, characterized by extensive fibrosis and nodular regeneration that significantly increases mortality risk. While magnetic resonance imaging (MRI) offers a non-invasive…

Accurate analysis of the fibrosis stage plays very important roles in follow-up of patients with chronic hepatitis B infection. In this paper, a deep learning framework is presented for automatically liver fibrosis prediction. On contrary…

Image and Video Processing · Electrical Eng. & Systems 2020-09-11 Jiali Liu , Wenxuan Wang , Tianyao Guan , Ningbo Zhao , Xiaoguang Han , Zhen Li

Objectives: To develop and evaluate a radiomics machine learning model for detecting liver fibrosis on CT of the liver. Methods: For this retrospective, single-centre study, radiomic features were extracted from Regions of Interest (ROIs)…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Jay J. Yoo , Khashayar Namdar , Sean Carey , Sandra E. Fischer , Chris McIntosh , Farzad Khalvati , Patrik Rogalla

Ultrasound (US) is a critical modality for diagnosing liver fibrosis. Unfortunately, assessment is very subjective, motivating automated approaches. We introduce a principled deep convolutional neural network (CNN) workflow that…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Bowen Li , Ke Yan , Dar-In Tai , Yuankai Huo , Le Lu , Jing Xiao , Adam P. Harrison

Staging of liver fibrosis is important in the diagnosis and treatment planning of patients suffering from liver diseases. Current deep learning-based methods using abdominal magnetic resonance imaging (MRI) usually take a sub-region of the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Zheyao Gao , Yuanye Liu , Fuping Wu , NanNan Shi , Yuxin Shi , Xiahai Zhuang

Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver diseases (CLD) which can progress to liver cancer. The severity and treatment of NAFLD is determined by NAFLD Activity Scores (NAS)and liver…

Image and Video Processing · Electrical Eng. & Systems 2021-03-16 Ananya Jana , Hui Qu , Carlos D. Minacapelli , Carolyn Catalano , Vinod Rustgi , Dimitris Metaxas

The current methods for characterization of frequency-dependent material properties of human liver are very limited. In fact, there is almost no data available in the literature showing the variation in dynamic elastic modulus of healthy or…

Medical Physics · Physics 2021-04-12 M. Umut Ozcan , Sina Ocal , Cagatay Basdogan , Gulen Dogusoy , Yaman Tokat

Objectives- Several ultrasound measures have shown promise for assessment of steatosis compared to traditional B-scan, however clinicians may be required to integrate information across the parameters. Here, we propose an integrated…

Medical Physics · Physics 2024-04-03 Jihye Baek , Ahmed El Kaffas , Aya Kamaya , Kenneth Hoyt , Kevin J. Parker

Liver fibrosis represents a significant global health burden, necessitating accurate staging for effective clinical management. This report introduces the LiQA (Liver Fibrosis Quantification and Analysis) dataset, established as part of the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Yuanye Liu , Hanxiao Zhang , Jiyao Liu , Nannan Shi , Yuxin Shi , Arif Mahmood , Murtaza Taj , Xiahai Zhuang

Medical imaging is the most important tool for detecting complications in the inner body of medicine. Nowadays, with the development of image processing technology as well as changing the size of photos to higher resolution images in the…

Image and Video Processing · Electrical Eng. & Systems 2022-07-19 Mahmoudreza Moghimhanjani , Ali Taghavirashidizadeh

Motivated by elastography that utilizes tissue mechanical properties as biomarkers for liver disease, with the eventual objective of quantitatively linking histopathology and bulk mechanical properties, we develop a micromechanical modeling…

Biological Physics · Physics 2025-01-06 Haritya Shah , Murthy N. Guddati

Liver fibrosis poses a substantial challenge in clinical practice, emphasizing the necessity for precise liver segmentation and accurate disease staging. Based on the CARE Liver 2025 Track 4 Challenge, this study introduces a multi-task…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Boya Wang , Ruizhe Li , Chao Chen , Xin Chen

Background: Artificial intelligence techniques have demonstrated great potential in cardiology, especially to detect imperceptible patterns for the human eye. In this sense, these techniques seem to be adequate to identify patterns in the…

Image and Video Processing · Electrical Eng. & Systems 2022-06-07 Ariel. H. Curiale , Facundo Cabrera , Pablo Jimenez , Jorgelina Medus , GermÁn Mato , MatÍas E. Calandrelli

In real-world clinical settings, magnetic resonance imaging (MRI) frequently suffers from missing modalities due to equipment variability or patient cooperation issues, which can significantly affect model performance. To address this…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Zhejia Zhang , Junjie Wang , Le Zhang

Due to the need for quick and effective treatments for liver diseases, which are among the most common health problems in the world, staging fibrosis through non-invasive and economic methods has become of great importance. Taking…

Computer Vision and Pattern Recognition · Computer Science 2021-01-08 Marco Trombini , Paolo Borro , Sebastiano Ziola , Silvana Dellepiane

Non-invasive radiological-based lesion characterization and identification, e.g., to differentiate cancer subtypes, has long been a major aim to enhance oncological diagnosis and treatment procedures. Here we study a specific population of…

Computer Vision and Pattern Recognition · Computer Science 2020-09-01 Yuankai Huo , Jinzheng Cai , Chi-Tung Cheng , Ashwin Raju , Ke Yan , Bennett A. Landman , Jing Xiao , Le Lu , Chien-Hung Liao , Adam P. Harrison
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