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Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

The depth-of-field (DoF) effect, which introduces aesthetically pleasing blur, enhances photographic quality but is fixed and difficult to modify once the image has been created. This becomes problematic when the applied blur is…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Yiyang Wang , Xi Chen , Xiaogang Xu , Yu Liu , Hengshuang Zhao

Microstructure imaging is crucial in materials science, but experimental images often introduce noise that obscures critical structural details. This study presents a novel deep learning approach for robust microstructure image denoising,…

Materials Science · Physics 2025-07-03 Owais Ahmad , Albert Linda , Saumya Ranjan Jha , Somnath Bhowmick

Annotation variability remains a substantial challenge in medical image segmentation, stemming from ambiguous imaging boundaries and diverse clinical expertise. Traditional deep learning methods producing single deterministic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Han Zhang , Xiangde Luo , Yong Chen , Kang Li

Deep metric learning (DML) has shown to be effective for content-based image retrieval (CBIR) in remote sensing (RS). Most of DML methods for CBIR rely on a high number of annotated images to accurately learn model parameters of deep neural…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Genc Hoxha , Gencer Sumbul , Julia Henkel , Lars Möllenbrok , Begüm Demir

Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Rushi Jiao , Yichi Zhang , Le Ding , Rong Cai , Jicong Zhang

Fully supervised deep neural networks for segmentation usually require a massive amount of pixel-level labels which are manually expensive to create. In this work, we develop a multi-task learning method to relax this constraint. We regard…

Computer Vision and Pattern Recognition · Computer Science 2021-04-07 Rihuan Ke , Aurélie Bugeau , Nicolas Papadakis , Mark Kirkland , Peter Schuetz , Carola-Bibiane Schönlieb

Cell image segmentation is usually implemented using fully supervised deep learning methods, which heavily rely on extensive annotated training data. Yet, due to the complexity of cell morphology and the requirement for specialized…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Yu Zhu , Qiang Yang , Li Xu

Nuclei segmentation is a fundamental but challenging task in the quantitative analysis of histopathology images. Although fully-supervised deep learning-based methods have made significant progress, a large number of labeled images are…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Xinyi Yu , Guanbin Li , Wei Lou , Siqi Liu , Xiang Wan , Yan Chen , Haofeng Li

Cell counting is a ubiquitous, yet tedious task that would greatly benefit from automation. From basic biological questions to clinical trials, cell counts provide key quantitative feedback that drive research. Unfortunately, cell counting…

Computer Vision and Pattern Recognition · Computer Science 2018-03-02 Carlos X. Hernández , Mohammad M. Sultan , Vijay S. Pande

Enabling efficient and accurate deep neural network (DNN) inference on microcontrollers is non-trivial due to the constrained on-chip resources. Current methodologies primarily focus on compressing larger models yet at the expense of model…

Machine Learning · Computer Science 2024-03-15 Xiao Ma , Shengfeng He , Hezhe Qiao , Dong Ma

Dynamic imaging is essential for analyzing various biological systems and behaviors but faces two main challenges: data incompleteness and computational burden. For many imaging systems, high frame rates and short acquisition times require…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Luke Lozenski , Mark A. Anastasio , Umberto Villa

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

Microbiome data analysis is essential for understanding host health and disease, yet its inherent sparsity and noise pose major challenges for accurate imputation, hindering downstream tasks such as biomarker discovery. Existing imputation…

Machine Learning · Computer Science 2025-08-01 Rabeya Tus Sadia , Qiang Cheng

Artificial intelligence is nowadays used for cell detection and classification in optical microscopy, during post-acquisition analysis. The microscopes are now fully automated and next expected to be smart, to make acquisition decisions…

This paper presents a systematic solution for the intelligent recognition and automatic analysis of microscopy images. We developed a data engine that generates high-quality annotated datasets through a combination of the collection of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-27 Yanhui Hong , Nan Wang , Zhiyi Xia , Haoyi Tao , Xi Fang , Yiming Li , Jiankun Wang , Peng Jin , Xiaochen Cai , Shengyu Li , Ziqi Chen , Zezhong Zhang , Guolin Ke , Linfeng Zhang

In this work, we propose a learning framework for identifying synapses using a deep and wide multi-scale recursive (DAWMR) network, previously considered in image segmentation applications. We apply this approach on electron microscopy data…

Computer Vision and Pattern Recognition · Computer Science 2014-09-08 Gary B. Huang , Stephen Plaza

Deterministic approaches using iterative optimisation have been historically successful in diffeomorphic image registration (DiffIR). Although these approaches are highly accurate, they typically carry a significant computational burden.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Alexander Thorley , Xi Jia , Hyung Jin Chang , Boyang Liu , Karina Bunting , Victoria Stoll , Antonio de Marvao , Declan P. O'Regan , Georgios Gkoutos , Dipak Kotecha , Jinming Duan

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual…

Computer Vision and Pattern Recognition · Computer Science 2024-12-12 Tyler Ward , Abdullah-Al-Zubaer Imran

Large annotated datasets are crucial for the success of deep neural networks, but labeling data can be prohibitively expensive in domains such as medical imaging. This work tackles the subset selection problem: selecting a small set of the…

Machine Learning · Computer Science 2025-09-29 Noga Bar , Raja Giryes