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The early detection of anomalous events in time series data is essential in many domains of application. In this paper we deal with critical health events, which represent a significant cause of mortality in intensive care units of…

Machine Learning · Statistics 2020-10-23 Vitor Cerqueira , Luis Torgo , Carlos Soares

Instilling resilience in critical infrastructure (CI) such as dams or power grids is a major challenge for tomorrow's cities and communities. Resilience, here, pertains to a CI's ability to adapt or rapidly recover from disruptive events.…

Optimization and Control · Mathematics 2017-09-04 AbdelRahman Eldosouky , Walid Saad , Narayan Mandayam

Accurate models of clinical actions and their impacts on disease progression are critical for estimating personalized optimal dynamic treatment regimes (DTRs) in medical/health research, especially in managing chronic conditions.…

Methodology · Statistics 2021-02-19 William Hua , Hongyuan Mei , Sarah Zohar , Magali Giral , Yanxun Xu

The coronavirus disease 2019 (COVID-19) pandemic has exerted a profound impact on patients with end-stage renal disease relying on kidney dialysis to sustain their lives. Motivated by a request by the U.S. Centers for Medicare & Medicaid…

Methodology · Statistics 2022-09-02 Wenbo Wu , John D. Kalbfleisch , Jeremy M. G. Taylor , Jian Kang , Kevin He

Nursing homes are critical facilities for caring frail older adults with round-the-clock formal care and personal assistance. To ensure quality care for nursing home residents, adequate staffing level is of great importance. Current nursing…

Applications · Statistics 2021-02-09 Xuxue Sun , Nan Kong , Nazmus Sakib , Chao Meng , Kathryn Hyer , Hongdao Meng , Chris Masterson , Mingyang Li

Mixed-criticality real-time scheduling has been developed to improve resource utilization while guaranteeing safe execution of critical applications. These studies use optimistic resource reservation for all the applications to improve…

Operating Systems · Computer Science 2020-04-07 Xiaozhe Gu , Arvind Easwaran , Kieu-My Phan , Insik Shin

Crises like the COVID-19 pandemic pose a serious challenge to health-care institutions. They need to plan the resources required for handling the increased load, for instance, hospital beds and ventilators. To support the resource planning…

We study the problem of eliciting the preferences of a decision-maker through a moderate number of pairwise comparison queries to make them a high quality recommendation for a specific problem. We are motivated by applications in high…

Optimization and Control · Mathematics 2021-12-09 Phebe Vayanos , Yingxiao Ye , Duncan McElfresh , John Dickerson , Eric Rice

Data-driven optimization models have the potential to significantly improve hospital capacity management, particularly during demand surges, when effective allocation of capacity is most critical and challenging. However, integrating models…

Computers and Society · Computer Science 2024-07-26 Felix Parker , Diego A. Martínez , James Scheulen , Kimia Ghobadi

Resource support between individuals is of particular importance in controlling or mitigating epidemic spreading, especially during pandemics. Whereas there remains the question of how we can protect ourselves from being infected while…

Physics and Society · Physics 2020-02-10 Xiaolong Chen , Quanhui Liu , Ruijie Wang , Qing Li , Wei Wang

We develop a simulation tool to support policy-decisions about healthcare for chronic diseases in defined populations. Incident disease-cases are generated in-silico from an age-sex characterised general population using standard…

Applications · Statistics 2010-09-03 Nathan Green , Duncan Smith , Matthew Sperrin , Iain Buchan

The optimisation in the ambulance dispatching process is significant for patients who need early treatments. However, the problem of dynamic ambulance redeployment for destination hospital selection has rarely been investigated. The paper…

Computers and Society · Computer Science 2022-01-07 Xinyu Fu , Valeria Krzhizhanovskaya , Alexey Yakovlev , Sergey Kovalchuk

The time-varying effects model is a flexible and powerful tool for modeling the dynamic changes of covariate effects. However, in survival analysis, its computational burden increases quickly as the number of sample sizes or predictors…

Computation · Statistics 2020-01-01 Kevin He , Ji Zhu , Jian Kang , Yi Li

Notable progress has been made in generalist medical large language models across various healthcare areas. However, large-scale modeling of in-hospital time series data - such as vital signs, lab results, and treatments in critical care -…

Considering the increasing frequency of cyberattacks affecting multiple hospitals simultaneously, improving resilience at a network level is essential. Various countermeasures exist to improve resilience against cyberattacks, such as…

Cryptography and Security · Computer Science 2026-01-19 Stephan Helfrich , Emilia Grass

Objective: In this paper, we develop a personalized real-time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs; the proposed…

Artificial Intelligence · Computer Science 2016-10-28 Ahmed M. Alaa , Jinsung Yoon , Scott Hu , Mihaela van der Schaar

Improving effectiveness and safety of patient care is an ultimate objective for medical cyber-physical systems. A recent study shows that the patients' death rate can be reduced by computerizing medical guidelines. Most existing medical…

Software Engineering · Computer Science 2018-11-21 Chunhui Guo , Zhicheng Fu , Zhenyu Zhang , Shangping Ren , Lui Sha

Emergency Medical Services (EMS) in the United States and similar systems typically utilize a single treatment pathway, transporting all patients to emergency departments (EDs), regardless of their actual care needs or preferences. Recent…

Optimization and Control · Mathematics 2025-06-25 Eric G. Stratman , Justin J. Boutilier , Laura A. Albert

The quality of service in healthcare is constantly challenged by outlier events such as pandemics (i.e. Covid-19) and natural disasters (such as hurricanes and earthquakes). In most cases, such events lead to critical uncertainties in…

Artificial Intelligence · Computer Science 2021-11-16 Chih-Hao Huang , Feras A. Batarseh , Adel Boueiz , Ajay Kulkarni , Po-Hsuan Su , Jahan Aman

Empirical evidence suggesting that living systems might operate in the vicinity of critical points, at the borderline between order and disorder, has proliferated in recent years, with examples ranging from spontaneous brain activity to…

Statistical Mechanics · Physics 2014-07-25 Jorge Hidalgo , Jacopo Grilli , Samir Suweis , Miguel A. Munoz , Jayanth R. Banavar , Amos Maritan