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This paper investigates efficient deep neural networks (DNNs) to replace dense unstructured weight matrices with structured ones that possess desired properties. The challenge arises because the optimal weight matrix structure in popular…

Machine Learning · Computer Science 2024-03-11 Changwoo Lee , Hun-Seok Kim

Biological networks often change under different environmental and genetic conditions. Understanding how these networks change becomes an important problem in biological studies. In this paper, we model the network change as the difference…

Methodology · Statistics 2017-05-30 Huili Yuan , Ruibin Xi , Chong Chen , Minghua Deng

We provide a review and a comparison of methods for differential network estimation in Gaussian graphical models with focus on structure learning. We consider the case of two datasets from distributions associated with two graphical models.…

Methodology · Statistics 2025-03-07 Anna Plaksienko , Magne Thoresen , Vera Djordjilović

We consider structure discovery of undirected graphical models from observational data. Inferring likely structures from few examples is a complex task often requiring the formulation of priors and sophisticated inference procedures.…

Machine Learning · Statistics 2017-08-04 Eugene Belilovsky , Kyle Kastner , Gaël Varoquaux , Matthew Blaschko

Graphical models have gained a lot of attention recently as a tool for learning and representing dependencies among variables in multivariate data. Often, domain scientists are looking specifically for differences among the dependency…

Machine Learning · Statistics 2013-07-11 Diane Oyen , Alexandru Niculescu-Mizil , Rachel Ostroff , Alex Stewart , Vincent P. Clark

Gene regulatory networks (GRNs) orchestrate cellular decision making and survival strategies. Inferring the structure of these networks from high-dimensional transcriptomics data is a central challenge in systems biology. Traditional…

Applications · Statistics 2025-08-01 Visweswaran Ravikumar , Aaresh Bhathena , Wajd N Al-Holou , Salar Fattahi , Arvind Rao

Graphical models are useful tools for describing structured high-dimensional probability distributions. Development of efficient algorithms for learning graphical models with least amount of data remains an active research topic.…

Machine Learning · Computer Science 2021-11-18 Marc Vuffray , Sidhant Misra , Andrey Y. Lokhov

In this paper, we focus on the unsupervised setting for structure learning of deep neural networks and propose to adopt the efficient coding principle, rooted in information theory and developed in computational neuroscience, to guide the…

Machine Learning · Computer Science 2021-05-31 Jinhui Yuan , Fei Pan , Chunting Zhou , Tao Qin , Tie-Yan Liu

Probabilistic theory and differential equation are powerful tools for the interpretability and guidance of the design of machine learning models, especially for illuminating the mathematical motivation of learning latent variable from…

Machine Learning · Computer Science 2025-02-13 Zhuangwei Shi

Sparse coding strategies have been lauded for their parsimonious representations of data that leverage low dimensional structure. However, inference of these codes typically relies on an optimization procedure with poor computational…

Machine Learning · Computer Science 2022-09-02 Kion Fallah , Christopher J. Rozell

Motivated by distributed machine learning settings such as Federated Learning, we consider the problem of fitting a statistical model across a distributed collection of heterogeneous data sets whose similarity structure is encoded by a…

Statistics Theory · Mathematics 2021-11-30 Dominic Richards , Sahand N. Negahban , Patrick Rebeschini

Deep neural networks have emerged as powerful tools for learning operators defined over infinite-dimensional function spaces. However, existing theories frequently encounter difficulties related to dimensionality and limited…

Machine Learning · Computer Science 2026-05-12 Jianfei Li , Shuo Huang , Han Feng , Ding-Xuan Zhou , Gitta Kutyniok

We introduce a principled approach for unsupervised structure learning of deep neural networks. We propose a new interpretation for depth and inter-layer connectivity where conditional independencies in the input distribution are encoded…

Machine Learning · Statistics 2018-10-18 Raanan Y. Rohekar , Shami Nisimov , Yaniv Gurwicz , Guy Koren , Gal Novik

Deep neural networks have significantly alleviated the burden of feature engineering, but comparable efforts are now required to determine effective architectures for these networks. Furthermore, as network sizes have become excessively…

Machine Learning · Computer Science 2023-10-25 Yognjin Lee

Differential graphical models are designed to represent the difference between the conditional dependence structures of two groups, thus are of particular interest for scientific investigation. Motivated by modern applications, this…

Statistics Theory · Mathematics 2021-02-03 Sen Na , Mladen Kolar , Oluwasanmi Koyejo

Tabular datasets with low-sample-size or many variables are prevalent in biomedicine. Practitioners in this domain prefer linear or tree-based models over neural networks since the latter are harder to interpret and tend to overfit when…

Machine Learning · Computer Science 2022-02-09 Junchen Yang , Ofir Lindenbaum , Yuval Kluger

Structured prediction involves learning to predict complex structures rather than simple scalar values. The main challenge arises from the non-Euclidean nature of the output space, which generally requires relaxing the problem formulation.…

Machine Learning · Statistics 2024-11-19 Junjie Yang , Matthieu Labeau , Florence d'Alché-Buc

Differential networks (DN) are important tools for modeling the changes in conditional dependencies between multiple samples. A Bayesian approach for estimating DNs, from the classical viewpoint, is introduced with a computationally…

Methodology · Statistics 2022-04-06 Jarod Smith , Mohammad Arashi , Andriette Bekker

We propose to meta-learn causal structures based on how fast a learner adapts to new distributions arising from sparse distributional changes, e.g. due to interventions, actions of agents and other sources of non-stationarities. We show…

Differential network is an important tool to capture the changes of conditional correlations under two sample cases. In this paper, we introduce a fast iterative algorithm to recover the differential network for high-dimensional data. The…

Computation · Statistics 2019-01-23 Zhou Tang , Zhangsheng Yu , Cheng Wang
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