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We explore the methodology and theory of reward-directed generation via conditional diffusion models. Directed generation aims to generate samples with desired properties as measured by a reward function, which has broad applications in…

Machine Learning · Computer Science 2023-07-17 Hui Yuan , Kaixuan Huang , Chengzhuo Ni , Minshuo Chen , Mengdi Wang

Conditional discrete generative models struggle to faithfully compose multiple input conditions. To address this, we derive a theoretically-grounded formulation for composing discrete probabilistic generative processes, with masked…

Machine Learning · Computer Science 2026-04-08 Jamie Stirling , Noura Al-Moubayed , Chris G. Willcocks , Hubert P. H. Shum

Conditional discrete generative models struggle to faithfully compose multiple input conditions. To address this, we derive a theoretically-grounded formulation for composing discrete probabilistic generative processes, with masked…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Jamie Stirling , Noura Al-Moubayed , Chris G. Willcocks , Hubert P. H. Shum

Dynamic manufacturing processes exhibit complex characteristics defined by time-varying parameters, nonlinear behaviors, and uncertainties. These characteristics require sophisticated in-situ monitoring techniques utilizing multimodal…

Machine Learning · Computer Science 2025-08-26 Suk Ki Lee , Hyunwoong Ko

We present a generative predictive control (GPC) framework that amortizes sampling-based Model Predictive Control (SPC) by bootstrapping it with conditional flow-matching models trained on SPC control sequences collected in simulation.…

The development of high-dimensional generative models has recently gained a great surge of interest with the introduction of variational auto-encoders and generative adversarial neural networks. Different variants have been proposed where…

Computer Vision and Pattern Recognition · Computer Science 2019-04-18 Mickaël Chen , Ludovic Denoyer , Thierry Artières

Developing deep generative models has been an emerging field due to the ability to model and generate complex data for various purposes, such as image synthesis and molecular design. However, the advancement of deep generative models is…

Text generation often requires high-precision output that obeys task-specific rules. This fine-grained control is difficult to enforce with off-the-shelf deep learning models. In this work, we consider augmenting neural generation models…

Computation and Language · Computer Science 2020-05-12 Xiang Lisa Li , Alexander M. Rush

Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial alignment and complex inter-channel relationships.…

Machine Learning · Computer Science 2025-07-08 Haoran Zhang , Mingyuan Zhou , Wesley Tansey

Designing molecules with specific properties is a long-lasting research problem and is central to advancing crucial domains such as drug discovery and material science. Recent advances in deep graph generative models treat molecule design…

Machine Learning · Computer Science 2022-03-02 Yuanqi Du , Xiaojie Guo , Amarda Shehu , Liang Zhao

We develop a new framework for learning variational autoencoders and other deep generative models that balances generative and discriminative goals. Our framework optimizes model parameters to maximize a variational lower bound on the…

Machine Learning · Computer Science 2020-12-15 Gabriel Hope , Madina Abdrakhmanova , Xiaoyin Chen , Michael C. Hughes , Michael C. Hughes , Erik B. Sudderth

The emergence of generative models enables the creation of texts and images tailored to users' preferences. Existing personalized generative models have two critical limitations: lacking a dedicated paradigm for accurate preference…

Information Retrieval · Computer Science 2026-04-23 Yuting Zhang , Ying Sun , Dazhong Shen , Ziwei Xie , Feng Liu , Changwang Zhang , Xiang Liu , Jun Wang , Hui Xiong

Generative models on discrete state-spaces have a wide range of potential applications, particularly in the domain of natural sciences. In continuous state-spaces, controllable and flexible generation of samples with desired properties has…

Machine Learning · Computer Science 2025-03-27 Hunter Nisonoff , Junhao Xiong , Stephan Allenspach , Jennifer Listgarten

Deep model-based reinforcement learning methods offer a conceptually simple approach to the decision-making and control problem: use learning for the purpose of estimating an approximate dynamics model, and offload the rest of the work to…

Machine Learning · Computer Science 2023-07-13 Michael Janner

Deep generative neural networks have proven effective at both conditional and unconditional modeling of complex data distributions. Conditional generation enables interactive control, but creating new controls often requires expensive…

Machine Learning · Computer Science 2017-12-25 Jesse Engel , Matthew Hoffman , Adam Roberts

This work considers the sample and computational complexity of obtaining an $\epsilon$-optimal policy in a discounted Markov Decision Process (MDP), given only access to a generative model. In this work, we study the effectiveness of the…

Machine Learning · Computer Science 2020-04-07 Alekh Agarwal , Sham Kakade , Lin F. Yang

Learning to sample from complex unnormalized distributions is a fundamental challenge in computational physics and machine learning. While score-based and variational methods have achieved success in continuous domains, extending them to…

Machine Learning · Statistics 2026-03-11 Lei Li , Zhen Wang , Lishuo Zhang

Accurate protein structures are essential for understanding biological function, yet incorporating experimental data into protein generative models remains a major challenge. Most predictors of experimental observables are…

Machine Learning · Computer Science 2025-11-18 Nadav Bojan Sellam , Meital Bojan , Paul Schanda , Alex Bronstein

Large pre-trained language models have repeatedly shown their ability to produce fluent text. Yet even when starting from a prompt, generation can continue in many plausible directions. Current decoding methods with the goal of controlling…

Computation and Language · Computer Science 2021-09-21 Damian Pascual , Beni Egressy , Clara Meister , Ryan Cotterell , Roger Wattenhofer

Recent deep generative models are able to provide photo-realistic images as well as visual or textual content embeddings useful to address various tasks of computer vision and natural language processing. Their usefulness is nevertheless…

Machine Learning · Computer Science 2020-01-29 Antoine Plumerault , Hervé Le Borgne , Céline Hudelot