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A variational autoencoder (VAE) is a probabilistic machine learning framework for posterior inference that projects an input set of high-dimensional data to a lower-dimensional, latent space. The latent space learned with a VAE offers…

Machine Learning · Computer Science 2022-11-16 Rafael Pastrana

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

The examination of histopathology images is considered to be the gold standard for the diagnosis and stratification of cancer patients. A key challenge in the analysis of such images is their size, which can run into the gigapixels and can…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Joseph Boyd , Mykola Liashuha , Eric Deutsch , Nikos Paragios , Stergios Christodoulidis , Maria Vakalopoulou

Histopathology images are crucial to the study of complex diseases such as cancer. The histologic characteristics of nuclei play a key role in disease diagnosis, prognosis and analysis. In this work, we propose a sparse Convolutional…

Computer Vision and Pattern Recognition · Computer Science 2017-04-11 Le Hou , Vu Nguyen , Dimitris Samaras , Tahsin M. Kurc , Yi Gao , Tianhao Zhao , Joel H. Saltz

We investigate the ability of Diffusion Variational Autoencoder ($\Delta$VAE) with unit sphere $\mathcal{S}^2$ as latent space to capture topological and geometrical structure and disentangle latent factors in datasets. For this, we…

Machine Learning · Computer Science 2024-09-04 Mahefa Ratsisetraina Ravelonanosy , Vlado Menkovski , Jacobus W. Portegies

Deep learning (DL) models for disease classification or segmentation from medical images are increasingly trained using transfer learning (TL) from unrelated natural world images. However, shortcomings and utility of TL for specialized…

Machine Learning · Statistics 2021-11-11 Sambuddha Ghosal , Pratik Shah

After deep generative models were successfully applied to image generation tasks, learning disentangled latent variables of data has become a crucial part of deep generative model research. Many models have been proposed to learn an…

Machine Learning · Computer Science 2019-07-08 Sangchul Hahn , Heeyoul Choi

Current research on deep learning for medical image segmentation exposes their limitations in learning either global semantic information or local contextual information. To tackle these issues, a novel network named SegTransVAE is proposed…

Image and Video Processing · Electrical Eng. & Systems 2023-10-03 Quan-Dung Pham , Hai Nguyen-Truong , Nam Nguyen Phuong , Khoa N. A. Nguyen

We propose TopDis (Topological Disentanglement), a method for learning disentangled representations via adding a multi-scale topological loss term. Disentanglement is a crucial property of data representations substantial for the…

Machine Learning · Computer Science 2025-03-17 Nikita Balabin , Daria Voronkova , Ilya Trofimov , Evgeny Burnaev , Serguei Barannikov

Variational autoencoders (VAEs) learn representations of data by jointly training a probabilistic encoder and decoder network. Typically these models encode all features of the data into a single variable. Here we are interested in learning…

Although automated pathology classification using deep learning (DL) has proved to be predictively efficient, DL methods are found to be data and compute cost intensive. In this work, we aim to reduce DL training costs by pre-training a…

Computer Vision and Pattern Recognition · Computer Science 2021-03-11 Sohini Roychowdhury , Kwok Sun Tang , Mohith Ashok , Anoop Sanka

Automated pathology segmentation remains a valuable diagnostic tool in clinical practice. However, collecting training data is challenging. Semi-supervised approaches by combining labelled and unlabelled data can offer a solution to data…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Haochuan Jiang , Agisilaos Chartsias , Xinheng Zhang , Giorgos Papanastasiou , Scott Semple , Mark Dweck , David Semple , Rohan Dharmakumar , Sotirios A. Tsaftaris

Deep neural networks (DNNs) have been widely adopted in brain lesion detection and segmentation. However, locating small lesions in 2D MRI slices is challenging, and requires to balance between the granularity of 3D context aggregation and…

Computer Vision and Pattern Recognition · Computer Science 2022-09-21 Haofeng Li , Junjia Huang , Guanbin Li , Zhou Liu , Yihong Zhong , Yingying Chen , Yunfei Wang , Xiang Wan

Although Digital Subtraction Angiography (DSA) is the most important imaging for visualizing cerebrovascular anatomy, its interpretation by clinicians remains difficult. This is particularly true when treating arteriovenous malformations…

Image and Video Processing · Electrical Eng. & Systems 2024-02-16 Kathleen Baur , Xin Xiong , Erickson Torio , Rose Du , Parikshit Juvekar , Reuben Dorent , Alexandra Golby , Sarah Frisken , Nazim Haouchine

Despite deep convolutional neural networks boost the performance of image classification and segmentation in digital pathology analysis, they are usually weak in interpretability for clinical applications or require heavy annotations to…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Yongxiang Huang , Albert C. S. Chung

The computer-aided detection (CADe) systems are developed to assist pathologists in slide assessment, increasing diagnosis efficiency and reducing missing inspections. Many studies have shown such a CADe system with deep learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Wei-Wen Hsu , Chung-Hao Chen , Chang Hoa , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Jingjing Wang , Tao He , Yanghong Tai

Detectingandsegmentingobjectswithinwholeslideimagesis essential in computational pathology workflow. Self-supervised learning (SSL) is appealing to such annotation-heavy tasks. Despite the extensive benchmarks in natural images for dense…

Computer Vision and Pattern Recognition · Computer Science 2022-07-15 Jiawei Yang , Hanbo Chen , Yuan Liang , Junzhou Huang , Lei He , Jianhua Yao

With the remarkable success of representation learning for prediction problems, we have witnessed a rapid expansion of the use of machine learning and deep learning for the analysis of digital pathology and biopsy image patches. However,…

Machine Learning · Computer Science 2024-03-06 David Ahmedt-Aristizabal , Mohammad Ali Armin , Simon Denman , Clinton Fookes , Lars Petersson

Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Richard J. Chen , Rahul G. Krishnan

Anomaly detection for Magnetic Resonance Images (MRIs) can be solved with unsupervised methods by learning the distribution of healthy images and identifying anomalies as outliers. In presence of an additional dataset of unlabelled data…

Machine Learning · Computer Science 2020-07-27 Alexandra-Ioana Albu , Alina Enescu , Luigi Malagò
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