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Circadian rhythmicity lies at the center of various important physiological and behavioral processes in mammals, such as sleep, metabolism, homeostasis, mood changes and more. It has been shown that this rhythm arises from self-sustained…

Neurons and Cognition · Quantitative Biology 2023-02-08 Yorgos M. Psarellis , Michail Kavousanakis , Michael A. Henson , Ioannis G. Kevrekidis

While Artificial Neural Networks (ANNs) have yielded impressive results in the realm of simulated intelligent behavior, it is important to remember that they are but sparse approximations of Biological Neural Networks (BNNs). We go beyond…

Neural and Evolutionary Computing · Computer Science 2021-03-30 Krishna Katyal , Jesse Parent , Bradly Alicea

Estimating the internal state of a robotic system is complex: this is performed from multiple heterogeneous sensor inputs and knowledge sources. Discretization of such inputs is done to capture saliences, represented as symbolic…

Computation and Language · Computer Science 2015-10-15 Simon Kaltenbacher , Nicholas H. Kirk , Dongheui Lee

Neuroengineering is faced with unique challenges in repairing or replacing complex neural systems that are composed of many interacting parts. These interactions form intricate patterns over large spatiotemporal scales, and produce emergent…

Neurons and Cognition · Quantitative Biology 2016-12-26 Danielle S. Bassett , Ankit N. Khambhati , Scott T. Grafton

The analyses presented herein demonstrate that neuronal electrical activity can be consistently interpreted as a manifestation of murburn redox-mediated electronic dynamics rather than as a process fundamentally driven by transmembrane…

Neurons and Cognition · Quantitative Biology 2026-05-04 Kelath Murali Manoj , Nagamani Sukumar

Neuroscience and Artificial Intelligence (AI) have made impressive progress in recent years but remain only loosely interconnected. Based on a workshop convened by the National Science Foundation in August 2025, we identify three…

Perceptual multistability, observed across species and sensory modalities, offers valuable insights into numerous cognitive functions and dysfunctions. For instance, differences in temporal dynamics and information integration during…

Neurons and Cognition · Quantitative Biology 2025-06-24 Shervin Safavi , Danaé Rolland , Philipp Sterzer , Renaud Jardri , Pantelis Leptourgos

Sensor-based reactive and hybrid approaches have proven a promising line of study to address imperfect knowledge in grasping and manipulation. However the reactive approaches are usually tightly coupled to a particular embodiment making…

Multimodal imaging has transformed neuroscience research. While it presents unprecedented opportunities, it also imposes serious challenges. Particularly, it is difficult to combine the merits of the interpretability attributed to a simple…

Methodology · Statistics 2021-11-25 Xiaowu Dai , Lexin Li

There are multiple scales of abstraction from which we can describe the same image, depending on whether we are focusing on fine-grained details or a more global attribute of the image. In brain mapping, learning to automatically parse…

We organized a workshop on the "Present and Future Frameworks of Theoretical Neuroscience", with the support of the National Science Foundation. The objective was to identify the challenges and strategies that this field will need to tackle…

Neurons and Cognition · Quantitative Biology 2020-04-06 Horacio G. Rotstein , Fidel Santamaria

The cell nucleus is increasingly recognized as a mechanosensitive organelle whose mesoscale mechanical heterogeneity (100 nm 10 um) is inseparable from genome regulation yet remains weakly integrated into systems biology and omics…

Recent studies revealed complex convergence dynamics in gradient-based methods, which has been little understood so far. Changing the step size to balance between high convergence rate and small generalization error may not be sufficient:…

Machine Learning · Computer Science 2021-04-07 Ilona Kulikovskikh

Economies are complex man-made systems where organisms and markets interact according to motivations and principles not entirely understood yet. The increasing dissatisfaction with the postulates of traditional economics i.e. perfectly…

Adaptation and Self-Organizing Systems · Physics 2012-06-04 Jaime Gomez-Ramirez , Manuel G. Bedia

The human brain is a dynamical system whose extremely complex sensor-driven neural processes give rise to conceptual, logical cognition. Understanding the interplay between nonlinear neural dynamics and concept-level cognition remains a…

Neural and Evolutionary Computing · Computer Science 2024-11-19 Herbert Jaeger

Recent advances in deep thinking models have demonstrated remarkable reasoning capabilities on mathematical and coding tasks. However, their effectiveness in embodied domains which require continuous interaction with environments through…

Computation and Language · Computer Science 2025-05-15 Wenqi Zhang , Mengna Wang , Gangao Liu , Xu Huixin , Yiwei Jiang , Yongliang Shen , Guiyang Hou , Zhe Zheng , Hang Zhang , Xin Li , Weiming Lu , Peng Li , Yueting Zhuang

Phenomics is concerned with detailed description of all aspects of organisms, from their physical foundations at genetic, molecular and cellular level, to behavioural and psychological traits. Neuropsychiatric phenomics, endorsed by NIMH,…

Neurons and Cognition · Quantitative Biology 2021-01-13 Włodzisław Duch

Deep neural learning uses an increasing amount of computation and data to solve very specific problems. By stark contrast, human minds solve a wide range of problems using a fixed amount of computation and limited experience. One ability…

Artificial Intelligence · Computer Science 2023-12-19 Zihan Ye , Hikaru Shindo , Devendra Singh Dhami , Kristian Kersting

Wright and Bourkes compelling article rightly points out that existing models of embryogenesis fail to explain the mechanisms and functional significance of the dynamic connections among neurons. We pursue their account of Dynamic Logic by…

Neurons and Cognition · Quantitative Biology 2020-07-31 Ines Hipolito , Maxwell Ramstead , Axel Constant , Karl Friston

Cognitive control researchers aim to describe the processes that support adaptive cognition to achieve specific goals. Control theorists consider how to influence the state of systems to reach certain user-defined goals. In brain networks,…

Neurons and Cognition · Quantitative Biology 2018-06-04 John D. Medaglia