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Models have been proposed to extract temporal patterns from longitudinal electronic health records (EHR) for clinical predictive models. However, the common relations among patients (e.g., receiving the same medical treatments) were rarely…

Applications · Statistics 2019-09-27 Yue Wang , Tong Wu , Yunlong Wang , Gao Wang

We present LLM-KT, a flexible framework designed to enhance collaborative filtering (CF) models by seamlessly integrating LLM (Large Language Model)-generated features. Unlike existing methods that rely on passing LLM-generated features as…

The advent of representation learning methods enabled large performance gains on various language tasks, alleviating the need for manual feature engineering. While engineered representations are usually based on some linguistic…

Computation and Language · Computer Science 2018-10-17 Ahmad Taie , Raphael Rubino , Josef van Genabith

Building trustworthy clinical AI systems requires not only accurate predictions but also transparent, biologically grounded explanations. We present \texttt{DiagnoLLM}, a hybrid framework that integrates Bayesian deconvolution, eQTL-guided…

Artificial Intelligence · Computer Science 2025-11-18 Bowen Xu , Xinyue Zeng , Jiazhen Hu , Tuo Wang , Adithya Kulkarni

The rapid development of artificial intelligence has led to marked progress in the field. One interesting direction for research is whether Large Language Models (LLMs) can be integrated with structured knowledge-based systems. This…

Computation and Language · Computer Science 2025-05-02 Wenli Yang , Lilian Some , Michael Bain , Byeong Kang

Navigating the complex landscape of single-cell transcriptomic data presents significant challenges. Central to this challenge is the identification of a meaningful representation of high-dimensional gene expression patterns that sheds…

Quantitative Methods · Quantitative Biology 2023-12-13 Mu Qiao

Large language models (LLMs) show promise for diagnostic reasoning but often lack reliable, knowledge grounded inference. Knowledge graphs (KGs), such as the Unified Medical Language System (UMLS), offer structured biomedical knowledge that…

Computation and Language · Computer Science 2025-09-24 Saksham Khatwani , He Cheng , Majid Afshar , Dmitriy Dligach , Yanjun Gao

There is a rising interest in further exploring the zero-shot learning potential of large pre-trained language models (PLMs). A new paradigm called data-generation-based zero-shot learning has achieved impressive success. In this paradigm,…

Computation and Language · Computer Science 2023-02-28 Jiahui Gao , Renjie Pi , Yong Lin , Hang Xu , Jiacheng Ye , Zhiyong Wu , Weizhong Zhang , Xiaodan Liang , Zhenguo Li , Lingpeng Kong

Large Language Models (LLMs) have been achieving competent performance on a wide range of downstream tasks, yet existing work shows that inference on structured data is challenging for LLMs. This is because LLMs need to either understand…

Computation and Language · Computer Science 2024-07-04 Younghun Lee , Sungchul Kim , Ryan A. Rossi , Tong Yu , Xiang Chen

Language models have advanced sequence analysis, yet DNA foundation models often lag behind task-specific methods for unclear reasons. We present AntigenLM, a generative DNA language model pretrained on influenza genomes with intact,…

Genomics · Quantitative Biology 2026-02-12 Yue Pei , Xuebin Chi , Yu Kang

Large Language Model (LLM) agents have shown great potential in addressing real-world data science problems. LLM-driven data science agents promise to automate the entire machine learning pipeline, yet their real-world effectiveness remains…

Computation and Language · Computer Science 2025-10-09 Yixin Ou , Yujie Luo , Jingsheng Zheng , Lanning Wei , Zhuoyun Yu , Shuofei Qiao , Jintian Zhang , Da Zheng , Yuren Mao , Yunjun Gao , Huajun Chen , Ningyu Zhang

Generative models based on deep learning have shown significant potential in medical imaging, particularly for modality transformation and multimodal fusion in MRI-based brain imaging. This study introduces GM-LDM, a novel framework that…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Hu Xu , Yang Jingling , Jia Sihan , Bi Yuda , Calhoun Vince

Discovering new materials can have significant scientific and technological implications but remains a challenging problem today due to the enormity of the chemical space. Recent advances in machine learning have enabled data-driven methods…

Materials Science · Physics 2024-06-21 Shuyi Jia , Chao Zhang , Victor Fung

Dataset availability and quality remain critical challenges in machine learning, especially in domains where data are scarce, expensive to acquire, or constrained by privacy regulations. Fields such as healthcare, biomedical research, and…

Databases · Computer Science 2025-10-23 Hamed Jelodar , Samita Bai , Roozbeh Razavi-Far , Ali A. Ghorbani

The increased availability of electronic health records (EHRs) have spearheaded the initiative for precision medicine using data driven approaches. Essential to this effort is the ability to identify patients with certain medical conditions…

The field of efficient Large Language Model (LLM) inference is rapidly evolving, presenting a unique blend of opportunities and challenges. Although the field has expanded and is vibrant, there hasn't been a concise framework that analyzes…

Computation and Language · Computer Science 2024-05-03 Zhihang Yuan , Yuzhang Shang , Yang Zhou , Zhen Dong , Zhe Zhou , Chenhao Xue , Bingzhe Wu , Zhikai Li , Qingyi Gu , Yong Jae Lee , Yan Yan , Beidi Chen , Guangyu Sun , Kurt Keutzer

Large language models have been extensively studied as neural knowledge bases for their knowledge access, editability, reasoning, and explainability. However, few works focus on the structural patterns of their knowledge. Motivated by this…

Computation and Language · Computer Science 2025-05-28 Utkarsh Sahu , Zhisheng Qi , Yongjia Lei , Ryan A. Rossi , Franck Dernoncourt , Nesreen K. Ahmed , Mahantesh M Halappanavar , Yao Ma , Yu Wang

Large language models (LLMs) have significantly advanced in various fields and intelligent agent applications. However, current LLMs that learn from human or external model supervision are costly and may face performance ceilings as task…

Computation and Language · Computer Science 2024-06-04 Zhengwei Tao , Ting-En Lin , Xiancai Chen , Hangyu Li , Yuchuan Wu , Yongbin Li , Zhi Jin , Fei Huang , Dacheng Tao , Jingren Zhou

In real-world NLP applications, Large Language Models (LLMs) offer promising solutions due to their extensive training on vast datasets. However, the large size and high computation demands of LLMs limit their practicality in many…

Artificial Intelligence · Computer Science 2025-04-01 Juanhui Li , Sreyashi Nag , Hui Liu , Xianfeng Tang , Sheikh Sarwar , Limeng Cui , Hansu Gu , Suhang Wang , Qi He , Jiliang Tang

Large language models (LLMs) have already revolutionized code generation, after being pretrained on publicly available code data. However, while various methods have been proposed to augment LLMs with retrieved knowledge and enhance the…

Computation and Language · Computer Science 2023-06-06 Shuyang Jiang , Yuhao Wang , Yu Wang