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Chemical Reaction Networks (CRNs) provide a useful abstraction of molecular interaction networks in which molecular structures as well as mass conservation principles are abstracted away to focus on the main dynamical properties of the…

Molecular Networks · Quantitative Biology 2020-07-31 Elisabeth Degrand , François Fages , Sylvain Soliman

We give a recursion formula to generate all equivalence classes of biconnected graphs with coefficients given by the inverses of the orders of their groups of automorphisms. We give a linear map to produce a connected graph with say, u,…

Combinatorics · Mathematics 2013-03-14 Angela Mestre

Models of biochemical networks are usually presented as connected graphs where vertices indicate proteins and edges are drawn to indicate activation or inhibition relationships. These diagrams are useful for drawing qualitative conclusions…

Dynamical Systems · Mathematics 2023-09-29 Chathranee Jayathilaka , Robyn Araujo , Lan Nguyen , Mark Flegg

Making sense of complex inhomogeneous systems composed of many interacting species is a grand challenge that pervades basically all natural sciences. Phase separation and pattern formation in reaction-diffusion systems have been largely…

Soft Condensed Matter · Physics 2025-06-04 Joshua F. Robinson , Thomas Machon , Thomas Speck

We consider chemical reaction networks taken with mass action kinetics. The steady states of such a system are solutions to a system of polynomial equations. Even for small systems the task of finding the solutions is daunting. We develop…

Dynamical Systems · Mathematics 2011-09-08 Elisenda Feliu , Carsten Wiuf

The article provides a unitary and complete solution to the fluctuation-dissipation relations for particle hydromechanics in a generic fluid, accounting for the hydrodynamic fluid-particle interactions (including arbitrary memory kernels in…

Statistical Mechanics · Physics 2024-12-30 Massimiliano Giona , Giuseppe Procopio , Chiara Pezzotti

Graph rewrite formalisms are a powerful approach to modeling complex molecular systems. They capture the intrinsic concurrency of molecular interactions, thereby enabling a formal notion of mechanism (a partially ordered set of events) that…

Logic in Computer Science · Computer Science 2019-01-04 Ioana Cristescu , Walter Fontana , Jean Krivine

To what extent do the characteristic features of a chemical reaction network reflect its purpose and function? In general, one argues that correlations between specific features and specific functions are key to understanding a complex…

Statistical Mechanics · Physics 2012-03-22 Sang Hoon Lee , Sebastian Bernhardsson , Petter Holme , Beom Jun Kim , Petter Minnhagen

We define a subclass of Chemical Reaction Networks called Post-Translational Modification systems. Important biological examples of such systems include MAPK cascades and two-component systems which are well-studied experimentally as well…

Molecular Networks · Quantitative Biology 2011-07-19 Elisenda Feliu , Carsten Wiuf

A reaction network is a chemical system involving multiple reactions and chemical species. Stochastic models of such networks treat the system as a continuous time Markov chain on the number of molecules of each species with reactions as…

Probability · Mathematics 2007-05-23 Karen Ball , Thomas G. Kurtz , Lea Popovic , Greg Rempala

Q-conditional symmetries (nonclassical symmetries) for a general class of two-component reaction-diffusion systems with constant diffusivities are studied. Using the recently introduced notion of Q-conditional symmetries of the first type…

Mathematical Physics · Physics 2019-09-17 Roman Cherniha , Vasyl' Davydovych

Sampled structure sequences obtained, for instance, from real-time reactivity explorations or first-principles molecular dynamics simulations contain valuable information about chemical reactivity. Eventually, such sequences allow for the…

Chemical Physics · Physics 2018-04-25 Michael A. Heuer , Alain C. Vaucher , Moritz P. Haag , Markus Reiher

The essence of a chemical reaction lies in the redistribution and reorganization of electrons, which is often manifested through electron transfer or the migration of electron pairs. These changes are inherently discrete and abrupt in the…

Machine Learning · Computer Science 2025-07-14 Haitao Lin , Junjie Wang , Zhifeng Gao , Xiaohong Ji , Rong Zhu , Linfeng Zhang , Guolin Ke , Weinan E

Chemically active mixtures exhibit complex patterns that emerge from the interplay of physical interactions and reactions among components. Individually, these two processes are well-understood: Physical interactions can give rise to phase…

Soft Condensed Matter · Physics 2026-04-30 Chengjie Luo , Yicheng Qiang , Guido L. A. Kusters , David Zwicker

An inverse problem framework for constructing reaction systems with prescribed properties is presented. Kinetic transformations are defined and analysed as a part of the framework, allowing an arbitrary polynomial ordinary differential…

Dynamical Systems · Mathematics 2015-10-27 Tomislav Plesa , Tomas Vejchodsky , Radek Erban

We investigate three different methods to tackle the problem of diffusion-limited reactions (annihilation) of hard-core classical particles in one dimension. We first extend an approach devised by Lushnikov and calculate for a single…

Statistical Mechanics · Physics 2009-10-31 Pierre-Antoine Bares , Mauro Mobilia

Reliably predicting the products of chemical reactions presents a fundamental challenge in synthetic chemistry. Existing machine learning approaches typically produce a reaction product by sequentially forming its subparts or intermediate…

Chemical Physics · Physics 2021-06-16 Hangrui Bi , Hengyi Wang , Chence Shi , Connor Coley , Jian Tang , Hongyu Guo

We propose a unified, human-readable, machine-processable novel syntax/notation designed to comprehensively describe reactions, molecules and excitation states. Our notation resolves inconsistencies in existing data representations and…

Computational Physics · Physics 2025-04-15 Dan Andrei Ciubotaru , Michele Renda , Călin Alexa

The Jacobian matrix of a dynamic system and its principal minors play a prominent role in the study of qualitative dynamics and bifurcation analysis. When interpreting the Jacobian as an adjacency matrix of an interaction graph, its…

Molecular Networks · Quantitative Biology 2012-10-02 Hans-Michael Kaltenbach

Analyzing qualitative behaviors of biochemical reactions using its associated network structure has proven useful in diverse branches of biology. As an extension of our previous work, we introduce a graph-based framework to calculate steady…

Classical Analysis and ODEs · Mathematics 2014-04-28 Inom Mirzaev , David Matthew Bortz
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