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Open Science aims to foster openness and collaboration in research, leading to more significant scientific and social impact. However, practicing Open Science comes with several challenges and is currently not properly rewarded. In this…

Software Engineering · Computer Science 2024-05-21 Edson OliveiraJr , Fernanda Madeiral , Alcemir Rodrigues Santos , Christina von Flach , Sergio Soares

We review methods of data analysis for biophysical data with a special emphasis on single molecule applications. Our review is intended for anyone, from student to established researcher. For someone just getting started, we focus on…

Biological Physics · Physics 2016-11-24 Meysam Tavakoli , J. Nicholas Taylor , Chun-Biu Li , Tamiki Komatsuzaki , Steve Pressé

Molecular dynamics (MD) has become a powerful tool for studying biophysical systems, due to increasing computational power and availability of software. Although MD has made many contributions to better understanding these complex…

Computational Physics · Physics 2019-09-27 Yihang Wang , Joao Marcelo Lamim Ribeiro , Pratyush Tiwary

While artificial intelligence (AI) has become widespread, many commercial AI systems are not yet accessible to individual researchers nor the general public due to the deep knowledge of the systems required to use them. We believe that AI…

Teaching data science presents unique challenges and opportunities that cannot be fully addressed by simply borrowing pedagogical strategies from its parent disciplines of statistics and computer science. Here, we present ten simple rules…

Other Statistics · Statistics 2026-02-04 Tiffany A. Timbers , Mine Çetinkaya-Rundel

Delivering effective data analytics is of crucial importance to the interpretation of the multitude of biological datasets currently generated by an ever increasing number of high throughput techniques. Logic programming has much to offer…

Logic in Computer Science · Computer Science 2019-09-19 Nicos Angelopoulos , Jan Wielemaker

Data is the most powerful decision-making tool at our disposal. However, despite the exponentially growing volumes of data generated in the world, putting it to effective use still presents many challenges. Relevant data seems to be never…

Databases · Computer Science 2021-11-12 Sergii Mikhtoniuk , Ozge Nilay Yalcin

This work-in-progress research paper explores the effectiveness of tutorials in interdisciplinary learning environments, specifically focusing on bioinformatics. Tutorials are typically designed for a single audience, but our study aims to…

Computers and Society · Computer Science 2025-03-07 Hannah Kim , Sergei L. Kosakovsky Pond , Stephen MacNeil

A call for coordinated action from government, academia, and industry.

Materials Science · Physics 2022-01-04 E. M. Campo , S. Shankar , A. S. Szalay , R. J. Hanisch

Recent advances in single cell sequencing and multi-omics techniques have significantly improved our understanding of biological phenomena and our capacity to model them. Despite combined capture of data modalities showing similar progress,…

Molecular Networks · Quantitative Biology 2025-03-13 Marcello Barylli , Joyaditya Saha , Tineke E. Buffart , Jan Koster , Kristiaan J. Lenos , Louis Vermeulen , Vivek M. Sheraton

In this paper we describe the design, and implementation of the Open Science Data Cloud, or OSDC. The goal of the OSDC is to provide petabyte-scale data cloud infrastructure and related services for scientists working with large quantities…

In the upcoming decades, the KM3NeT detectors will produce valuable data that can be used in various scientific contexts from astro- and particle physics to environmental and Earth and Sea science. Based on the Open Science policy…

Instrumentation and Methods for Astrophysics · Physics 2021-10-27 Jutta Schnabel , Piotr Kalaczyński , Cristiano Bozza , Tamas Gal

Recent technological advancements in data acquisition tools allowed life scientists to acquire multimodal data from different biological application domains. Broadly categorized in three types (i.e., sequences, images, and signals), these…

Quantitative Methods · Quantitative Biology 2020-03-03 Mufti Mahmud , M Shamim Kaiser , Amir Hussain

Life-science experimental methods generate vast and ever-increasing volumes of data, which provide highly valuable research resources. However, management of these data is nontrivial and applicable software solutions are currently subject…

Study reproducibility is essential to corroborate, build on, and learn from the results of scientific research but is notoriously challenging in bioinformatics, which often involves large data sets and complex analytic workflows involving…

Quantitative Methods · Quantitative Biology 2023-05-22 Christopher R. Keefe , Matthew R. Dillon , Chloe Herman , Mary Jewell , Colin V. Wood , Evan Bolyen , J. Gregory Caporaso

Metadata, often termed "data about data," is crucial for organizing, understanding, and managing vast omics datasets. It aids in efficient data discovery, integration, and interpretation, enabling users to access, comprehend, and utilize…

The objective of this short report is to reconsider the subject of bioinformatics as just being a tool of experimental biological science. To do that, we introduce three examples to show how bioinformatics could be considered as an…

Other Quantitative Biology · Quantitative Biology 2016-07-19 Olaf Ilzins , Raul Isea , Johan Hoebeke

Open source software is a rapidly evolving center for distributed work, and understanding the characteristics of this work across its different contexts is vital for informing policy, economics, and the design of enabling software. The…

Software Engineering · Computer Science 2025-04-24 Wenyi Lu , Enock Kasaadah , S M Rakib Ul Karim , Matt Germonprez , Sean Goggins

Data science is a discipline that provides principles, methodology and guidelines for the analysis of data for tools, values, or insights. Driven by a huge workforce demand, many academic institutions have started to offer degrees in data…

Other Statistics · Statistics 2020-05-27 Donghui Yan , Gary E. Davis