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As the amount of scientific data continues to grow at ever faster rates, the research community is increasingly in need of flexible computational infrastructure that can support the entirety of the data science lifecycle, including…

Computers and Society · Computer Science 2016-04-12 Robert L. Grossman , Allison Heath , Mark Murphy , Maria Patterson , Walt Wells

Researchers in biomedical research, public health, and the life sciences often spend weeks or months discovering, accessing, curating, and integrating data from disparate sources, significantly delaying the onset of actual analysis and…

Bioinformatics is a new discipline that addresses the need to manage and interpret the data that in the past decade was massively generated by genomic research. This discipline represents the convergence of genomics, biotechnology and…

Computational Engineering, Finance, and Science · Computer Science 2009-11-24 Sabu M. Thampi

Like medicine, psychology, or education, data science is fundamentally an applied discipline, with most students who receive advanced degrees in the field going on to work on practical problems. Unlike these disciplines, however, data…

Computers and Society · Computer Science 2020-01-28 Kit T Rodolfa , Adolfo De Unanue , Matt Gee , Rayid Ghani

Novel technologies in genomics allow creating data in exascale dimension with relatively minor effort of human and laboratory and thus monetary resources compared to capabilities only a decade ago. While the availability of this data…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-11-10 Sandra Gesing , Thomas Richard Connor , Ian Taylor

The Open Science Grid (OSG) includes work to enable new science, new scientists, and new modalities in support of computationally based research. There are frequently significant sociological and organizational changes required in…

Biologists are increasingly using databases for storing and managing their data. Biological databases typically consist of a mixture of raw data, metadata, sequences, annotations, and related data obtained from various sources. Current…

Databases · Computer Science 2007-05-23 Mohamed Y. Eltabakh , Mourad Ouzzani , Walid G. Aref

Scientific data governance should prioritize maximizing the utility of data throughout the research lifecycle. Research software systems that enable analysis reproducibility inform data governance policies and assist administrators in…

Biodiversity research requires complete and detailed information to study ecosystem dynamics at different scales. Employing data-driven methods like Machine Learning is getting traction in ecology and more specific biodiversity, offering…

Quantitative Methods · Quantitative Biology 2025-10-27 Stylianos Stasinos , Martino Mensio , Elena Lazovik , Athanasios Trantas

Motivation: Bioinformatics is faced with a variety of problems that require human involvement. Tasks like genome annotation, image analysis, knowledge-base construction and protein structure determination all benefit from human input. In…

Quantitative Methods · Quantitative Biology 2013-07-01 Benjamin M. Good , Andrew I. Su

With the increasing availability and size of multi-omics datasets, investigating the casual relationships between molecular phenotypes has become an important aspect of exploring underlying biology and genetics. This paper aims to introduce…

Molecular Networks · Quantitative Biology 2022-01-31 Jack Kelly , Carlo Berzuini , Bernard Keavney , Maciej Tomaszewski , Hui Guo

Biology is data-rich, and it is equally rich in concepts and hypotheses. Part of trying to understand biological processes and systems is therefore to confront our ideas and hypotheses with data using statistical methods to determine the…

Quantitative Methods · Quantitative Biology 2022-06-22 Sean T. Vittadello , Michael P. H. Stumpf

The fields of computing and biology have begun to cross paths in new ways. In this paper a review of the current research in biological computing is presented. Fundamental concepts are introduced and these foundational elements are explored…

Computational Engineering, Finance, and Science · Computer Science 2009-11-10 Balaji Akula , James Cusick

The Agent Based Model community has a rich and diverse ecosystem of libraries, platforms, and applications to help modelers develop rigorous simulations. Despite this robust and diverse ecosystem, the complexity of life from microbial…

Computers and Society · Computer Science 2021-11-16 Thomas Pike , Samantha Golden , Daniel Lowdermilk , Brandon Luong , Benjamin Rosado

Freely and openly shared low-cost electronic applications, known as open electronics, have sparked a new open-source movement, with much un-tapped potential to advance scientific research. Initially designed to appeal to electronic…

Quantitative Methods · Quantitative Biology 2022-07-14 Michael Oellermann , Jolle W. Jolles , Diego Ortiz , Rui Seabra , Tobias Wenzel , Hannah Wilson , Richelle Tanner

With the ever-growing presence of deep artificial neural networks in every facet of modern life, a growing body of researchers in educational data science -- a field consisting of various interrelated research communities -- have turned…

Computers and Society · Computer Science 2024-05-01 Juan D. Pinto , Luc Paquette

This paper is a brief update on developments in the BioDynaMo project, a new platform for computer simulations for biological research. We will discuss the new capabilities of the simulator, important new concepts simulation methodology as…

Neural and Evolutionary Computing · Computer Science 2018-01-22 Leonard Johard , Lukas Breitwieser , Alberto Di Meglio , Marco Manca , Manuel Mazzara , Max Talanov

Theory and empirical science should be in constant dialogue, but often find it hard to understand one another. Here we describe a graduate-level university course we developed to improve matters. The course was designed to help…

Physics Education · Physics 2026-04-16 Joanna Masel , Anna Dornhaus

The aim of this article is to present an overview of the existing biomedical data warehouses and to discuss the issues and future trends in this area. We illustrate this topic by presenting the design of an innovative, complex data…

Databases · Computer Science 2017-01-30 Jérôme Darmont , Emerson Olivier