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An important open question in computational neuroscience is how various spatially tuned neurons, such as place cells, are used to support the learning of reward-seeking behavior of an animal. Existing computational models either lack…

Neurons and Cognition · Quantitative Biology 2022-05-18 Yuanxiang Gao

Predictive coding has emerged as an influential normative model of neural computation, with numerous extensions and applications. As such, much effort has been put into mapping PC faithfully onto the cortex, but there are issues that remain…

Neurons and Cognition · Quantitative Biology 2023-03-07 Siavash Golkar , Tiberiu Tesileanu , Yanis Bahroun , Anirvan M. Sengupta , Dmitri B. Chklovskii

The brain anticipates future events using internal models that specify not only what will occur, but also when it will occur and with what probability. We refer to this joint specification of identity, timing, and likelihood as a complete…

Neurons and Cognition · Quantitative Biology 2026-02-27 Yohei Yamada , Zenas C. Chao

Predictive coding offers a potentially unifying account of cortical function -- postulating that the core function of the brain is to minimize prediction errors with respect to a generative model of the world. The theory is closely related…

Artificial Intelligence · Computer Science 2022-07-14 Beren Millidge , Anil Seth , Christopher L Buckley

A fundamental aspect of learning in biological neural networks is the plasticity property which allows them to modify their configurations during their lifetime. Hebbian learning is a biologically plausible mechanism for modeling the…

Neural and Evolutionary Computing · Computer Science 2021-03-16 Anil Yaman , Giovanni Iacca , Decebal Constantin Mocanu , Matt Coler , George Fletcher , Mykola Pechenizkiy

Understanding how receptive fields emerge and organize within brain networks and how neural dynamics couple with stimuli space is fundamental to neuroscience. Models often rely on fine-tuning connectivity to match empirical data, which may…

Neurons and Cognition · Quantitative Biology 2026-01-07 Vasilii Tiselko , Alexander Gorsky , Yuri Dabaghian

Due to its geometric properties, hyperbolic space can support high-fidelity embeddings of tree- and graph-structured data, upon which various hyperbolic networks have been developed. Existing hyperbolic networks encode geometric priors not…

Machine Learning · Computer Science 2023-03-14 Tao Yu , Christopher De Sa

Adaptive cognition requires structured internal models of objects and their relations. Predictive neural networks are often proposed to learn such world models, but how these are instantiated and how they support prediction remain unclear.…

Machine Learning · Computer Science 2026-05-11 Linda Ariel Ventura , Victoria Bosch , Tim C Kietzmann , Sushrut Thorat

How do neural networks trained over sequences acquire the ability to perform structured operations, such as arithmetic, geometric, and algorithmic computation? To gain insight into this question, we introduce the sequential group…

Machine Learning · Computer Science 2026-02-04 Giovanni Luca Marchetti , Daniel Kunin , Adele Myers , Francisco Acosta , Nina Miolane

We posit that hippocampal place cells encode information about future locations under a transition distribution observed as an agent explores a given (physical or conceptual) space. The encoding of information about the current location,…

Machine Learning · Computer Science 2019-06-07 Mariano Tepper

Neuronal circuits can learn and replay firing patterns evoked by sequences of sensory stimuli. After training, a brief cue can trigger a spatiotemporal pattern of neural activity similar to that evoked by a learned stimulus sequence.…

Neurons and Cognition · Quantitative Biology 2015-07-03 Alan Veliz-Cuba , Harel Shouval , Kresimir Josic , Zachary P. Kilpatrick

A multi-layer perceptron (MLP) is a type of neural networks which has a long history of research and has been studied actively recently in computer vision and graphics fields. One of the well-known problems of an MLP is the capability of…

Graphics · Computer Science 2023-10-31 Shin Fujieda , Atsushi Yoshimura , Takahiro Harada

Predictive coding (PC) is a brain-inspired local learning algorithm that has recently been suggested to provide advantages over backpropagation (BP) in biologically relevant scenarios. While theoretical work has mainly focused on showing…

Neural and Evolutionary Computing · Computer Science 2023-06-01 Francesco Innocenti , Ryan Singh , Christopher L. Buckley

Recently, hyperbolic space has risen as a promising alternative for semi-supervised graph representation learning. Many efforts have been made to design hyperbolic versions of neural network operations. However, the inspiring geometric…

Machine Learning · Computer Science 2022-01-24 Jiahong Liu , Menglin Yang , Min Zhou , Shanshan Feng , Philippe Fournier-Viger

Continuous attractor networks (CANs) are widely used to model how the brain temporarily retains continuous behavioural variables via persistent recurrent activity, such as an animal's position in an environment. However, this memory…

Neural and Evolutionary Computing · Computer Science 2025-07-02 Madison Cotteret , Christopher J. Kymn , Hugh Greatorex , Martin Ziegler , Elisabetta Chicca , Friedrich T. Sommer

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

Learning to produce spatiotemporal sequences is a common task that the brain has to solve. The same neural substrate may be used by the brain to produce different sequential behaviours. The way the brain learns and encodes such tasks…

Neurons and Cognition · Quantitative Biology 2020-07-01 Amadeus Maes , Mauricio Barahona , Claudia Clopath

This paper reviews predictive coding, from theoretical neuroscience, and variational autoencoders, from machine learning, identifying the common origin and mathematical framework underlying both areas. As each area is prominent within its…

Neural and Evolutionary Computing · Computer Science 2021-10-26 Joseph Marino

Understanding how biological constraints shape neural computation is a central goal of computational neuroscience. Spatially embedded recurrent neural networks provide a promising avenue to study how modelled constraints shape the combined…

Neural and Evolutionary Computing · Computer Science 2024-09-27 Cornelia Sheeran , Andrew S. Ham , Duncan E. Astle , Jascha Achterberg , Danyal Akarca

This paper considers neural representation through the lens of active inference, a normative framework for understanding brain function. It delves into how living organisms employ generative models to minimize the discrepancy between…

Neurons and Cognition · Quantitative Biology 2023-10-24 Giovanni Pezzulo , Leo D'Amato , Francesco Mannella , Matteo Priorelli , Toon Van de Maele , Ivilin Peev Stoianov , Karl Friston