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Hyperspectral images (HSIs) often suffer from noise arising from both intra-imaging mechanisms and environmental factors. Leveraging domain knowledge specific to HSIs, such as global spectral correlation (GSC) and non-local spatial…

Image and Video Processing · Electrical Eng. & Systems 2024-05-14 Guanyiman Fu , Fengchao Xiong , Jianfeng Lu , Jun Zhou , Jiantao Zhou , Yuntao Qian

Holistic 3D scene understanding involves capturing and parsing unstructured 3D environments. Due to the inherent complexity of the real world, existing models have predominantly been developed and limited to be task-specific. We introduce…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Sebastian Koch , Johanna Wald , Hidenobu Matsuki , Pedro Hermosilla , Timo Ropinski , Federico Tombari

Recent technological advances in cutting-edge ultrasensitive fluorescence microscopy have allowed single-molecule imaging experiments in living cells across all three domains of life to become commonplace. Single-molecule live-cell data is…

Biomolecules · Quantitative Biology 2015-04-15 Mark Leake

Quantifying the uncertainty of an object's pose estimate is essential for robust control and planning. Although pose estimation is a well-studied robotics problem, attaching statistically rigorous uncertainty is not well understood without…

Robotics · Computer Science 2025-11-27 Lorenzo Shaikewitz , Charis Georgiou , Luca Carlone

Feature grid Scene Representation Networks (SRNs) have been applied to scientific data as compact functional surrogates for analysis and visualization. As SRNs are black-box lossy data representations, assessing the prediction quality is…

Machine Learning · Computer Science 2024-08-07 Tianyu Xiong , Skylar W. Wurster , Hanqi Guo , Tom Peterka , Han-Wei Shen

Most speech enhancement (SE) models learn a point estimate and do not make use of uncertainty estimation in the learning process. In this paper, we show that modeling heteroscedastic uncertainty by minimizing a multivariate Gaussian…

Sound · Computer Science 2023-03-09 Kuan-Lin Chen , Daniel D. E. Wong , Ke Tan , Buye Xu , Anurag Kumar , Vamsi Krishna Ithapu

Prostate cancer is the most common malignant tumors in men but prostate Magnetic Resonance Imaging (MRI) analysis remains challenging. Besides whole prostate gland segmentation, the capability to differentiate between the blurry boundary of…

Latent variable models such as the Variational Auto-Encoder (VAE) have become a go-to tool for analyzing biological data, especially in the field of single-cell genomics. One remaining challenge is the interpretability of latent variables…

Genomics · Quantitative Biology 2023-02-20 Romain Lopez , Nataša Tagasovska , Stephen Ra , Kyunghyn Cho , Jonathan K. Pritchard , Aviv Regev

Multidimensional scaling is a statistical process that aims to embed high dimensional data into a lower-dimensional space; this process is often used for the purpose of data visualisation. Common multidimensional scaling algorithms tend to…

Machine Learning · Computer Science 2022-02-25 Pierre Lambert , Cyril de Bodt , Michel Verleysen , John Lee

Label noise is pervasive in various real-world scenarios, posing challenges in supervised deep learning. Deep networks are vulnerable to such label-corrupted samples due to the memorization effect. One major stream of previous methods…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Zeren Sun , Yazhou Yao , Tongliang Liu , Zechao Li , Fumin Shen , Jinhui Tang

This paper proposes a novel Sequence-to-Sequence Neural Diarization (S2SND) framework to perform online and offline speaker diarization. It is developed from the sequence-to-sequence architecture of our previous target-speaker voice…

Audio and Speech Processing · Electrical Eng. & Systems 2025-06-24 Ming Cheng , Yuke Lin , Ming Li

Low-field (LF) MRI scanners have the power to revolutionize medical imaging by providing a portable and cheaper alternative to high-field MRI scanners. However, such scanners are usually significantly noisier and lower quality than their…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Aryan Kalluvila , Neha Koonjoo , Danyal Bhutto , Marcio Rockenbach , Matthew S. Rosen

Single-cell RNA-seq data analysis typically requires representations that capture heterogeneous local structure across multiple scales while remaining stable and interpretable. In this work, we propose a hierarchical sheaf spectral…

Machine Learning · Computer Science 2026-03-31 Xiang Xiang Wang , Guo-Wei We

Motivation: Single cell RNA sequencing (scRNA-seq) data makes studying the development of cells possible at unparalleled resolution. Given that many cellular differentiation processes are hierarchical, their scRNA-seq data is expected to be…

Quantitative Methods · Quantitative Biology 2022-04-25 Quentin Garrido , Sebastian Damrich , Alexander Jäger , Dario Cerletti , Manfred Claassen , Laurent Najman , Fred Hamprecht

This paper aims to improve the performance of text-to-SQL parsing by exploring the intrinsic uncertainties in the neural network based approaches (called SUN). From the data uncertainty perspective, it is indisputable that a single SQL can…

Computation and Language · Computer Science 2022-10-31 Bowen Qin , Lihan Wang , Binyuan Hui , Bowen Li , Xiangpeng Wei , Binhua Li , Fei Huang , Luo Si , Min Yang , Yongbin Li

Efficient intravascular access in trauma and critical care significantly impacts patient outcomes. However, the availability of skilled medical personnel in austere environments is often limited. Autonomous robotic ultrasound systems can…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Rohini Banerjee , Cecilia G. Morales , Artur Dubrawski

Uncertainty quantification is a fundamental yet unsolved problem for deep learning. The Bayesian framework provides a principled way of uncertainty estimation but is often not scalable to modern deep neural nets (DNNs) that have a large…

Machine Learning · Computer Science 2020-08-25 Lingkai Kong , Jimeng Sun , Chao Zhang

Single-cell gene expression measurements encode variability spanning molecular noise, cell-to-cell heterogeneity, and technical artifacts. Mechanistic stochastic models provide powerful approaches to disentangle these sources, yet inferring…

Quantitative Methods · Quantitative Biology 2025-09-19 Christopher E. Miles

Graph Neural Networks have achieved impressive results across diverse network modeling tasks, but accurately estimating uncertainty on graphs remains difficult, especially under distributional shifts. Unlike traditional uncertainty…

Machine Learning · Computer Science 2025-10-15 Fred Xu , Thomas Markovich

Cell type identification from single-cell transcriptomic data is a common goal of single-cell RNA sequencing (scRNAseq) data analysis. Neural networks have been employed to identify cell types from scRNAseq data with high performance.…

Genomics · Quantitative Biology 2020-05-11 Xishuang Dong , Shanta Chowdhury , Uboho Victor , Xiangfang Li , Lijun Qian