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We introduce DeCaFlow, a deconfounding causal generative model. Training once per dataset using just observational data and the underlying causal graph, DeCaFlow enables accurate causal inference on continuous variables under the presence…

Machine Learning · Computer Science 2025-10-27 Alejandro Almodóvar , Adrián Javaloy , Juan Parras , Santiago Zazo , Isabel Valera

The task of conditional generation is one of the most important applications of generative models, and numerous methods have been developed to date based on the celebrated flow-based models. However, many flow-based models in use today are…

Machine Learning · Computer Science 2024-07-08 Noboru Isobe , Masanori Koyama , Jinzhe Zhang , Kohei Hayashi , Kenji Fukumizu

Diffusion models excel in high-quality generation but suffer from slow inference due to iterative sampling. While recent methods have successfully transformed diffusion models into one-step generators, they neglect model size reduction,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Yuanzhi Zhu , Xingchao Liu , Qiang Liu

Understanding and predicting object motion from egocentric video is fundamental to embodied perception and interaction. However, generating physically consistent 6DoF trajectories remains challenging due to occlusions, fast motion, and the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Abhishek Saroha , Huajian Zeng , Xingxing Zuo , Daniel Cremers , Xi Wang

Biologists frequently desire protein inhibitors for a variety of reasons, including use as research tools for understanding biological processes and application to societal problems in agriculture, healthcare, etc. Immunotherapy, for…

Machine Learning · Computer Science 2024-11-04 Po-Yu Liang , Jun Bai

Current state-of-the-art generative models map noise to data distributions by matching flows or scores. A key limitation of these models is their inability to readily integrate available partial observations and additional priors. In…

We present DataFlow, a computational framework for building, testing, and deploying high-performance machine learning systems on unbounded time-series data. Traditional data science workflows assume finite datasets and require substantial…

Machine Learning · Computer Science 2026-01-01 Giacinto Paolo Saggese , Paul Smith

Modeling stochastic dynamics from discrete observations is a key interdisciplinary challenge. Existing methods often fail to estimate the continuous evolution of probability densities from trajectories or face the curse of dimensionality.…

Computational Engineering, Finance, and Science · Computer Science 2025-12-02 Ruikun Li , Jiazhen Liu , Huandong Wang , Qingmin Liao , Yong Li

Methods for jointly generating molecular graphs along with their 3D conformations have gained prominence recently due to their potential impact on structure-based drug design. Current approaches, however, often suffer from very slow…

Machine Learning · Computer Science 2025-03-03 Ross Irwin , Alessandro Tibo , Jon Paul Janet , Simon Olsson

Diffusion models have revolutionized generative tasks through high-fidelity outputs, yet flow matching (FM) offers faster inference and empirical performance gains. However, current foundation FM models are computationally prohibitive for…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Johannes Schusterbauer , Ming Gui , Frank Fundel , Björn Ommer

Defect segmentation is central to computer vision based inspection of infrastructure assets during both construction and operation. However, deployment remains limited due to scarce pixel-level labels and domain shift across environments.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Babak Asadi , Peiyang Wu , Mani Golparvar-Fard , Ramez Hajj

Many biological systems evolve through continuous local dynamics while switching between latent regimes defined by learning, stimulus context, internal state, or developmental stage. These processes are often observed only as unpaired…

Machine Learning · Computer Science 2026-05-12 Josue Ortega Caro , Yongxu Zhang , Hannah M Batchelor , Sizhuang He , Jessica Cardin , Shreya Saxena

Recent advances in generative modeling have led to promising results in robot motion planning, particularly through diffusion and flow matching (FM)-based models that capture complex, multimodal trajectory distributions. However, these…

Robotics · Computer Science 2025-11-13 Xiaobing Dai , Zewen Yang , Dian Yu , Fangzhou Liu , Hamid Sadeghian , Sami Haddadin , Sandra Hirche

The rapidly growing demand for high-quality data in Large Language Models (LLMs) has intensified the need for scalable, reliable, and semantically rich data preparation pipelines. However, current practices remain dominated by ad-hoc…

In recent years, AI-assisted drug design methods have been proposed to generate molecules given the pockets' structures of target proteins. Most of them are atom-level-based methods, which consider atoms as basic components and generate…

Biomolecules · Quantitative Biology 2024-03-19 Haitao Lin , Yufei Huang , Odin Zhang , Lirong Wu , Siyuan Li , Zhiyuan Chen , Stan Z. Li

Scientific workflows are a cornerstone of modern scientific computing. They are used to describe complex computational applications that require efficient and robust management of large volumes of data, which are typically stored/processed…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-03-03 Rafael Ferreira da Silva , Loïc Pottier , Tainã Coleman , Ewa Deelman , Henri Casanova

Diffusion policies are expressive yet incur high inference latency. Flow Matching (FM) enables one-step generation, but integrating it into Maximum Entropy Reinforcement Learning (MaxEnt RL) is challenging: the optimal policy is an…

Machine Learning · Computer Science 2026-02-03 Zeqiao Li , Yijing Wang , Haoyu Wang , Zheng Li , Zhiqiang Zuo

Deep generative models that produce novel molecular structures have the potential to facilitate chemical discovery. Diffusion models currently achieve state of the art performance for 3D molecule generation. In this work, we explore the use…

Biomolecules · Quantitative Biology 2024-05-01 Ian Dunn , David Ryan Koes

Liquid electrolytes are critical components of next-generation energy storage systems, enabling fast ion transport, minimizing interfacial resistance, and ensuring electrochemical stability for long-term battery performance. However,…

Efficient discovery of electrocatalysts for electrochemical energy conversion reactions is of utmost importance to combat climate change. With the example of the oxygen reduction reaction we show that by utilising a data-driven discovery…