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Depression is one of the most prevalent mental health disorders globally. In recent years, multi-modal data, such as speech, video, and transcripts, has been increasingly used to develop AI-assisted depression assessment systems. Large…

Traditional psychological experiments utilizing naturalistic stimuli face challenges in manual annotation and ecological validity. To address this, we introduce a novel paradigm leveraging multimodal large language models (LLMs) as proxies…

Artificial Intelligence · Computer Science 2025-02-27 Xin Liu , Ziyue Zhang , Jingxin Nie

Background and Aims: Large language models (LLMs) have shown remarkable generalization and transfer capabilities by learning from vast corpora of text and web data. Their semantic representations allow cross-task knowledge transfer and…

Machine Learning · Computer Science 2025-09-25 Yuqi Jin , Zhenhao Shuai , Zihan Hu , Weiteng Zhang , Weihao Xie , Jianwei Shuai , Xian Shen , Zhen Feng

In practice, clinicians achieve a diagnosis by following a sequence of steps, such as laboratory exams, observations, or imaging. The pathways to reach diagnosis decisions are documented by guidelines authored by expert organizations, which…

Computation and Language · Computer Science 2024-09-25 Elisa Castagnari , Lillian Muyama , Adrien Coulet

Large language models (LLMs) have recently demonstrated their potential in clinical applications, providing valuable medical knowledge and advice. For example, a large dialog LLM like ChatGPT has successfully passed part of the US medical…

Computer Vision and Pattern Recognition · Computer Science 2023-02-15 Sheng Wang , Zihao Zhao , Xi Ouyang , Qian Wang , Dinggang Shen

Addressing the complexity of accurately classifying International Classification of Diseases (ICD) codes from medical discharge summaries is challenging due to the intricate nature of medical documentation. This paper explores the use of…

Machine Learning · Computer Science 2024-11-12 Zeyd Boukhers , AmeerAli Khan , Qusai Ramadan , Cong Yang

Large language models (LLMs) hold great promise for medical applications and are evolving rapidly, with new models being released at an accelerated pace. However, benchmarking on large-scale real-world data such as electronic health records…

Subjective language understanding refers to a broad set of natural language processing tasks where the goal is to interpret or generate content that conveys personal feelings, opinions, or figurative meanings rather than objective facts.…

Computation and Language · Computer Science 2025-08-12 Changhao Song , Yazhou Zhang , Hui Gao , Ben Yao , Peng Zhang

Reliable detection of the prodromal stages of Alzheimer's disease (AD) remains difficult even today because, unlike other neurocognitive impairments, there is no definitive diagnosis of AD in vivo. In this context, existing research has…

Machine Learning · Computer Science 2021-08-03 Amish Mittal , Sourav Sahoo , Arnhav Datar , Juned Kadiwala , Hrithwik Shalu , Jimson Mathew

Attention-based encoder-decoder (AED) models learn an implicit internal language model (ILM) from the training transcriptions. The integration with an external LM trained on much more unpaired text usually leads to better performance. A…

Computation and Language · Computer Science 2021-06-18 Mohammad Zeineldeen , Aleksandr Glushko , Wilfried Michel , Albert Zeyer , Ralf Schlüter , Hermann Ney

Depression is one of the leading causes of disability worldwide, posing a severe burden on individuals, healthcare systems, and society at large. Recent advancements in Large Language Models (LLMs) have shown promise in addressing mental…

Computation and Language · Computer Science 2025-02-11 Shiyu Teng , Jiaqing Liu , Rahul Kumar Jain , Shurong Chai , Ruibo Hou , Tomoko Tateyama , Lanfen Lin , Yen-wei Chen

Emotion recognition in speech is a challenging multimodal task that requires understanding both verbal content and vocal nuances. This paper introduces a novel approach to emotion detection using Large Language Models (LLMs), which have…

Computation and Language · Computer Science 2024-12-24 Zehui Wu , Ziwei Gong , Lin Ai , Pengyuan Shi , Kaan Donbekci , Julia Hirschberg

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. Early detection of AD is crucial for effective intervention and treatment. In this paper, we propose a novel approach…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-29 Yu Pu , Wei-Qiang Zhang

Recent advancements in large language models (LLMs) have shown their potential across both general and domain-specific tasks. However, there is a growing concern regarding their lack of sensitivity, factual incorrectness in responses,…

Computation and Language · Computer Science 2025-12-01 Vivek Kumar , Pushpraj Singh Rajawat , Eirini Ntoutsi

Objective: Large Language Models (LLMs) demonstrate significant capabilities in medical text understanding and generation. However, their diagnostic reliability in complex clinical scenarios remains limited. This study aims to enhance LLMs'…

Computation and Language · Computer Science 2025-08-04 Peixian Li , Yu Tian , Ruiqi Tu , Chengkai Wu , Jingjing Ren , Jingsong Li

Large language models (LLMs) are increasingly used in decision-making tasks where they can amplify or suppress perspectives, raising concerns in high-stakes settings affecting autistic communities. While previous research has identified…

Computation and Language · Computer Science 2026-05-27 Naba Rizvi , Harper Strickland , Saleha Ahmedi , Nedjma Ousidhoum

Driven by privacy protection laws and regulations, unlearning in Large Language Models (LLMs) is gaining increasing attention. However, current research often neglects the interpretability of the unlearning process, particularly concerning…

Machine Learning · Computer Science 2025-04-10 Xiaohua Feng , Yuyuan Li , Chengye Wang , Junlin Liu , Li Zhang , Chaochao Chen

Background Major depressive disorder (MDD) is a leading cause of global disability, yet current diagnostic approaches often rely on subjective assessments and lack the ability to integrate multimodal clinical information. Large language…

Machine Learning · Computer Science 2025-09-30 Yuyang Sha , Hongxin Pan , Gang Luo , Caijuan Shi , Jing Wang , Kefeng Li

Self-supervised automatic speech recognition (SSL-ASR) is an ASR approach that uses speech encoders pretrained on large amounts of unlabeled audio (e.g., wav2vec2.0 or HuBERT) and then fine-tunes them with limited labeled data to perform…

Audio and Speech Processing · Electrical Eng. & Systems 2026-01-07 Eyal Cohen , Bhiksha Raj , Joseph Keshet

Post-training quantization (PTQ) is an effective technique for compressing large language models (LLMs). However, while uniform-precision quantization is computationally efficient, it often compromises model performance. To address this, we…

Machine Learning · Computer Science 2025-05-27 Wei Huang , Haotong Qin , Yangdong Liu , Yawei Li , Qinshuo Liu , Xianglong Liu , Luca Benini , Michele Magno , Shiming Zhang , Xiaojuan Qi