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Protein folding is a central challenge in computational biology, with important applications in molecular biology, drug discovery and catalyst design. As a hard combinatorial optimisation problem, it has been studied as a potential target…

With the advent of quantum computers, researchers are exploring if quantum mechanics can be leveraged to solve important problems in ways that may provide advantages not possible with conventional or classical methods. A previous work by…

Quantum Physics · Physics 2018-11-02 Ajinkya Borle , Samuel J. Lomonaco

This paper explores the applications of quantum annealing (QA) and classical simulated annealing (SA) to a suite of combinatorial optimization problems in machine learning, namely feature selection, instance selection, and clustering. We…

Quantum Physics · Physics 2025-07-22 Chloe Pomeroy , Aleksandar Pramov , Karishma Thakrar , Lakshmi Yendapalli

We study the effect of the anneal path control per qubit, a new user control feature offered on the D-Wave 2000Q quantum annealer, on the performance of quantum annealing for solving optimization problems by numerically solving the…

Variational quantum algorithms (VQAs) are a modern family of quantum algorithms designed to solve optimization problems using a quantum computer. Typically VQAs rely on a feedback loop between the quantum device and a classical optimization…

Quantum Physics · Physics 2022-08-26 Alexey Uvarov

In this paper we present a novel strategy to solve optimization problems within a hybrid quantum-classical scheme based on quantum annealing, with a particular focus on QUBO problems. The proposed algorithm is based on an iterative…

Quantum Physics · Physics 2020-04-07 Enrico Blanzieri , Davide Pastorello

There are well developed theoretical tools to analyse how quantum dynamics can solve computational problems by varying Hamiltonian parameters slowly, near the adiabatic limit. On the other hand, there are relatively few tools to understand…

Quantum Physics · Physics 2021-03-10 Adam Callison , Max Festenstein , Jie Chen , Laurentiu Nita , Viv Kendon , Nicholas Chancellor

Solving inverse problems to identify Hamiltonians with desired properties holds promise for the discovery of fundamental principles. In quantum systems, quantum entanglement plays a pivotal role in not only characterizing the quantum nature…

Strongly Correlated Electrons · Physics 2024-08-20 Koji Inui , Yukitoshi Motome

Quantum annealing is an optimization technique which potentially leverages quantum tunneling to enhance computational performance. Existing quantum annealers use superconducting flux qubits with short coherence times, limited primarily by…

Recent work has shown that quantum annealing for machine learning, referred to as QAML, can perform comparably to state-of-the-art machine learning methods with a specific application to Higgs boson classification. We propose QAML-Z, a…

Quantum Physics · Physics 2021-01-04 Alexander Zlokapa , Alex Mott , Joshua Job , Jean-Roch Vlimant , Daniel Lidar , Maria Spiropulu

Traffic congestion is one of the major issues in urban areas, particularly when traffic loads exceed the roads capacity, resulting in higher petrol consumption and carbon emissions as well as delays and stress for road users. In Asia, the…

Quantum Physics · Physics 2024-03-15 Amit Singh , Chun-Yu Lin , Chung-I Huang , Fang-Pang Lin

Driving a quantum system periodically in time can profoundly alter its long-time dynamics and trigger topological order. Such schemes are particularly promising for generating non-trivial energy bands and gauge structures in quantum-matter…

Quantum Gases · Physics 2015-06-11 N. Goldman , J. Dalibard

A deep understanding of the mechanisms underlying many-body quantum chaos is one of the big challenges in contemporary theoretical physics. We tackle this problem in the context of a set of perturbed quadratic Sachdev-Ye-Kitaev (SYK)…

Quantum Physics · Physics 2025-02-05 Alexei Andreanov , Matteo Carrega , Jeff Murugan , Jan Olle , Dario Rosa , Ruth Shir

Quantum computing has long promised transformative advances in data analysis, yet practical quantum machine learning has remained elusive due to fundamental obstacles such as a steep quantum cost for the loading of classical data and poor…

Discrete combinatorial optimization consists in finding the optimal configuration that minimizes a given discrete objective function. An interpretation of such a function as the energy of a classical system allows us to reduce the…

Quantum Physics · Physics 2015-06-22 Sergio Boixo , Gerardo Ortiz , Rolando Somma

We suggest a hybrid quantum-classical routine for the NP-hard Electric Vehicle Fleet Charging and Allocation Problem. The original formulation is a Mixed Integer Linear Program with continuous variables and inequality constraints. To…

Quantum annealing is a heuristic algorithm for searching the ground state of an Ising model. Heuristic algorithms aim to obtain near-optimal solutions with a reasonable computation time. Accordingly, many algorithms have so far been…

Quantum Physics · Physics 2022-11-09 Shuntaro Okada , Masayuki Ohzeki

Quantum annealing is a promising paradigm for building practical quantum computers. Compared to other approaches, quantum annealing technology has been scaled up to a larger number of qubits. On the other hand, deep learning has been…

Quantum Physics · Physics 2021-07-07 Michele Sasdelli , Tat-Jun Chin

In this paper, we explore the potential for quantum annealing to solve realistic routing problems. We focus on two NP-Hard problems, including the Traveling Salesman Problem with Time Windows and the Capacitated Vehicle Routing Problem with…

Emerging Technologies · Computer Science 2025-04-01 James B. Holliday , Darren Blount , Eneko Osaba , Khoa Luu

The logistic network design is an abstract optimization problem that, under the assumption of minimal cost, seeks the optimal configuration of the supply chain's infrastructures and facilities based on customer demand. Key economic…

Quantum Physics · Physics 2021-02-04 Yongcheng Ding , Xi Chen , Lucas Lamata , Enrique Solano , Mikel Sanz