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We study bidisperse colloidal suspensions confined within glass microcapillary tubes to model the glass transition in confined cylindrical geometries. We use high speed three-dimensional confocal microscopy to observe particle motions for a…

Soft Condensed Matter · Physics 2013-02-28 Nabiha Saklayen , Gary L. Hunter , Kazem V. Edmond , Eric R. Weeks

Transitions between solid-like and fluid-like states in living tissues have been found in steps of embryonic development and in stages of disease progression. Our current understanding of these transitions has been guided by experimental…

Soft Condensed Matter · Physics 2024-11-20 Steven J. Chisolm , Emily Guo , Vignesh Subramaniam , Kyle D. Schulze , Thomas E. Angelini

Systems comprised of self-steering active Brownian particles are studied via simulations for a minimal cognitive flocking model. The dynamics of the active Brownian particles is extended by an orientational response with limited…

Soft Condensed Matter · Physics 2024-06-04 Rajendra Singh Negi , Roland G. Winkler , Gerhard Gompper

This study investigates the dynamics of alternating minimization applied to a bilinear regression task with normally distributed covariates, under the asymptotic system size limit where the number of parameters and observations diverge at…

Optimization and Control · Mathematics 2025-02-03 Koki Okajima , Takashi Takahashi

We present a simple discrete model for the non-linear spatial interaction of different kinds of ``subpopulations'' composed of identical moving entities like particles, bacteria, individuals, etc. The model allows to mimic a variety of…

Statistical Mechanics · Physics 2007-05-23 Dirk Helbing , Tadeusz Platkowski

Cell plasma membranes display a dramatically rich structural complexity characterized by functional sub-wavelength domains with specific lipid and protein composition. Under favorable experimental conditions, patterned morphologies can also…

Soft Condensed Matter · Physics 2018-10-02 Nicolas Destainville , Manoel Manghi , Julie Cornet

We study the spontaneous motion, binary collisions, and collective dynamics of "polar disks", i.e. purpose-built particles which, when vibrated between two horizontal plates, move coherently along a direction strongly correlated to their…

Soft Condensed Matter · Physics 2016-01-19 Julien Deseigne , Sébastien Léonard , Olivier Dauchot , Hugues Chaté

Spatial self-organization emerges in distributed systems exhibiting local interactions when nonlinearities and the appropriate propagation of signals are at work. These kinds of phenomena can be modeled with different frameworks, typically…

Cell Behavior · Quantitative Biology 2016-11-23 Adriano Bonforti , Salva Duran-Nebreda , Raul Montañez , Ricard Solé

A simple model of an active colloid consisting of dumbbell-shaped particles that cyclically change their length without propelling themselves is proposed and analyzed. At nanoscales, it represents an idealization for bacterial cytoplasm or…

Adaptation and Self-Organizing Systems · Physics 2020-01-28 Yuki Koyano , Hiroyuki Kitahata , Alexander S. Mikhailov

We monitored isotropic spreading of mouse embryonic fibroblasts on fibronectin-coated substrates. Cell adhesion area versus time was measured via total internal reflection fluorescence microscopy. Spreading proceeds in well-defined phases.…

Cell Behavior · Quantitative Biology 2009-11-10 H. -G. Doebereiner , B. J. Dubin-Thaler , G. Giannone , H. S. Xenias , M. P. Sheetz

The dynamics of a tracer particle in a glassy matrix of obstacles displays slow complex transport as the free volume approaches a critical value and the void space falls apart. We investigate the emerging subdiffusive motion of the test…

Statistical Mechanics · Physics 2011-01-20 Thomas Franosch , Markus Spanner , Teresa Bauer , Gerd E. Schröder-Turk , Felix Höfling

We study the large space and time scale behavior of a totally asymmetric, nearest-neighbor exclusion process in one dimension with random jump rates attached to the particles. When slow particles are sufficiently rare the system has a phase…

Probability · Mathematics 2007-05-23 Ilie Grigorescu , Min Kang , Timo Seppalainen

Cell migration in confining physiological environments relies on the concerted dynamics of several cellular components, including protrusions, adhesions with the environment, and the cell nucleus. However, it remains poorly understood how…

Living systems are capable of locomotion, reconfiguration, and replication. To perform these tasks, cells spatiotemporally coordinate the interactions of force-generating, "active" molecules that create and manipulate non-equilibrium…

Soft Condensed Matter · Physics 2019-08-28 Tyler D. Ross , Heun Jin Lee , Zijie Qu , Rachel A. Banks , Rob Phillips , Matt Thomson

A prerequisite for isolating diseased cells requires a mechanism for effective mass-based separation. This objective, however, is generally rather challenging because typically no valid correlation exists between the size of the particles…

Statistical Mechanics · Physics 2019-03-27 Aleksandra Słapik , Jerzy Łuczka , Peter Hänggi , Jakub Spiechowicz

Growth patterns generated by filamentous organisms (e.g. actinomycetes and fungi) involve spatial and temporal dynamics at different length scales. Several mathematical models have been proposed in the last thirty years to address these…

Populations and Evolution · Quantitative Biology 2007-05-23 Michele Bezzi , Andrea Ciliberto

We study a model of interacting random walkers that proposes a simple mechanism for the emergence of cooperation in group of individuals. Each individual, represented by a Brownian particle, experiences an interaction produced by the local…

Statistical Mechanics · Physics 2007-05-23 Fabio Cecconi , Giuseppe Gonnella , Gustavo P. Saracco

We introduce and analyze several aspects of a new model for cell differentiation. It assumes that differentiation of progenitor cells is a continuous process. From the mathematical point of view, it is based on partial differential…

Analysis of PDEs · Mathematics 2013-01-21 Marie Doumic , Anna Marciniak-Czochra , Benoit Perthame , Jorge P. Zubelli

This work analyzes fractional continuous-time random walks on two-layer multiplexes. A node-centric dynamics is used, in which it is assumed a Poisson distribution of a walker to become active, while a jump to one of its neighbors depends…

Physics and Society · Physics 2020-01-29 Alfonso Allen-Perkins , Roberto F. S. Andrade

We study the dynamics of an ideal polymer chain in a crowded, viscoelastic medium and in the presence of active forces. The motion of the centre of mass and of individual monomers is calculated. On time scales that are comparable to the…

Soft Condensed Matter · Physics 2015-12-23 Hans Vandebroek , Carlo Vanderzande
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