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The Segment Anything Model (SAM) has demonstrated strong and versatile segmentation capabilities, along with intuitive prompt-based interactions. However, customizing SAM for medical image segmentation requires massive amounts of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Zhonghao Yan , Zijin Yin , Tianyu Lin , Xiangzhu Zeng , Kongming Liang , Zhanyu Ma

Segmentation models such as Segment Anything Model (SAM) and SAM2 achieve strong prompt-driven zero-shot performance. However, their training on natural images limits domain transfer to medical data. Consequently, accurate segmentation…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Tal Grossman , Noa Cahan , Lev Ayzenberg , Hayit Greenspan

Medical image segmentation often faces the challenge of prohibitively expensive annotation costs. While few-shot learning offers a promising solution to alleviate this burden, conventional approaches still rely heavily on pre-training with…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Jie Xu , Xiaokang Li , Chengyu Yue , Yuanyuan Wang , Yi Guo

Foundational models such as the Segment Anything Model (SAM) are gaining traction in medical imaging segmentation, supporting multiple downstream tasks. However, such models are supervised in nature, still relying on large annotated…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Aishik Konwer , Zhijian Yang , Erhan Bas , Cao Xiao , Prateek Prasanna , Parminder Bhatia , Taha Kass-Hout

MedSAM, a medical foundation model derived from the SAM architecture, has demonstrated notable success across diverse medical domains. However, its clinical application faces two major challenges: the dependency on labor-intensive manual…

Image and Video Processing · Electrical Eng. & Systems 2025-04-17 Peng Huang , Shu Hu , Bo Peng , Xun Gong , Penghang Yin , Hongtu Zhu , Xi Wu , Xin Wang

Due to the flexibility of prompting, foundation models have become the dominant force in the domains of natural language processing and image generation. With the recent introduction of the Segment Anything Model (SAM), the prompt-driven…

Image and Video Processing · Electrical Eng. & Systems 2023-08-14 Yichi Zhang , Rushi Jiao

Medical image segmentation is a crucial and time-consuming task in clinical care, where mask precision is extremely important. The Segment Anything Model (SAM) offers a promising approach, as it provides an interactive interface based on…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Julien Khlaut , Elodie Ferreres , Daniel Tordjman , Hélène Philippe , Tom Boeken , Pierre Manceron , Corentin Dancette

The emerging scale segmentation model, Segment Anything (SAM), exhibits impressive capabilities in zero-shot segmentation for natural images. However, when applied to medical images, SAM suffers from noticeable performance drop. To make SAM…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Xinrong Hu , Xiaowei Xu , Yiyu Shi

Medical image segmentation has been traditionally approached by training or fine-tuning the entire model to cater to any new modality or dataset. However, this approach often requires tuning a large number of parameters during training.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Jay N. Paranjape , Shameema Sikder , S. Swaroop Vedula , Vishal M. Patel

Deep learning-based medical image segmentation typically requires large amount of labeled data for training, making it less applicable in clinical settings due to high annotation cost. Semi-supervised learning (SSL) has emerged as an…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Yichi Zhang , Bohao Lv , Le Xue , Wenbo Zhang , Yuchen Liu , Yu Fu , Yuan Cheng , Yuan Qi

The Segment Anything Model (SAM) is a recently proposed prompt-based segmentation model in a generic zero-shot segmentation approach. With the zero-shot segmentation capacity, SAM achieved impressive flexibility and precision on various…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Can Cui , Ruining Deng , Quan Liu , Tianyuan Yao , Shunxing Bao , Lucas W. Remedios , Yucheng Tang , Yuankai Huo

Semi-supervised learning (SSL) has achieved notable progress in medical image segmentation. To achieve effective SSL, a model needs to be able to efficiently learn from limited labeled data and effectively exploiting knowledge from abundant…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Juzheng Miao , Cheng Chen , Keli Zhang , Jie Chuai , Quanzheng Li , Pheng-Ann Heng

Although SAM-based single-source domain generalization models for medical image segmentation can mitigate the impact of domain shift on the model in cross-domain scenarios, these models still face two major challenges. First, the…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Huanli Zhuo , Leilei Ma , Haifeng Zhao , Shiwei Zhou , Dengdi Sun , Yanping Fu

The Segment Anything Model (SAM) is a powerful foundation model for image segmentation, showing robust zero-shot generalization through prompt engineering. However, relying on manual prompts is impractical for real-world applications,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Yi Chen , Mu-Young Son , Chuanbo Hua , Joo-Young Kim

Deep learning-based medical image segmentation models often suffer from domain shift, where the models trained on a source domain do not generalize well to other unseen domains. As a prompt-driven foundation model with powerful…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Yifan Gao , Wei Xia , Dingdu Hu , Wenkui Wang , Xin Gao

While the Segment Anything Model (SAM) excels in semantic segmentation for general-purpose images, its performance significantly deteriorates when applied to medical images, primarily attributable to insufficient representation of medical…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Yiming Zhang , Tianang Leng , Kun Han , Xiaohui Xie

Although new vision foundation models such as Segment Anything Model 2 (SAM2) have significantly enhanced zero-shot image segmentation capabilities, reliance on human-provided prompts poses significant challenges in adapting SAM2 to medical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Yang Xing , Jiong Wu , Yuheng Bu , Kuang Gong

The limited availability of labeled data has driven advancements in semi-supervised learning for medical image segmentation. Modern large-scale models tailored for general segmentation, such as the Segment Anything Model (SAM), have…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Kaiwen Huang , Tao Zhou , Huazhu Fu , Yizhe Zhang , Yi Zhou , Chen Gong , Dong Liang

With the proposal of the Segment Anything Model (SAM), fine-tuning SAM for medical image segmentation (MIS) has become popular. However, due to the large size of the SAM model and the significant domain gap between natural and medical…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Jinfeng Wang , Sifan Song , Xinkun Wang , Yiyi Wang , Yiyi Miao , Jionglong Su , S. Kevin Zhou

The Segment Anything Model (SAM) is widely used for segmenting a diverse range of objects in natural images from simple user prompts like points or bounding boxes. However, SAM's performance decreases substantially when applied to…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Tristan Piater , Björn Barz , Alexander Freytag