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The recently introduced Segment Anything Model (SAM) combines a clever architecture and large quantities of training data to obtain remarkable image segmentation capabilities. However, it fails to reproduce such results for…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Tal Shaharabany , Aviad Dahan , Raja Giryes , Lior Wolf

Medical image segmentation plays a pivotal role in clinical diagnostics and treatment planning, yet existing models often face challenges in generalization and in handling both 2D and 3D data uniformly. In this paper, we introduce Medical…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Jiayuan Zhu , Abdullah Hamdi , Yunli Qi , Yueming Jin , Junde Wu

The Segment Anything Model (SAM) has drawn significant attention from researchers who work on medical image segmentation because of its generalizability. However, researchers have found that SAM may have limited performance on medical…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Yihao Liu , Jiaming Zhang , Andres Diaz-Pinto , Haowei Li , Alejandro Martin-Gomez , Amir Kheradmand , Mehran Armand

Medical image segmentation is fundamental for biomedical discovery. Existing methods lack generalizability and demand extensive, time-consuming manual annotation for new clinical application. Here, we propose MedSAM-3, a text promptable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Anglin Liu , Rundong Xue , Xu R. Cao , Yifan Shen , Yi Lu , Xiang Li , Qianqian Chen , Jintai Chen

Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Hanxue Gu , Haoyu Dong , Jichen Yang , Maciej A. Mazurowski

The Segment Anything Model (SAM) has recently emerged as a groundbreaking foundation model for prompt-driven image segmentation tasks. However, both the original SAM and its medical variants require slice-by-slice manual prompting of target…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Yichi Zhang , Shiyao Hu , Sijie Ren , Chen Jiang , Yuan Cheng , Yuan Qi

The Segment Anything Model (SAM) excels at generating precise object masks from input prompts but lacks semantic awareness, failing to associate its generated masks with specific object categories. To address this limitation, we propose…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Rohit Kundu , Sudipta Paul , Arindam Dutta , Amit K. Roy-Chowdhury

Automatic medical image segmentation is a fundamental step in computer-aided diagnosis, yet fully supervised approaches demand extensive pixel-level annotations that are costly and time-consuming. To alleviate this burden, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Lei Shi , Gang Li , Junxing Zhang

The development of high quality medical image segmentation algorithms depends on the availability of large datasets with pixel-level labels. The challenges of collecting such datasets, especially in case of 3D volumes, motivate to develop…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Ekaterina Redekop , Alexey Chernyavskiy

Tissue-level semantic segmentation is a vital step in computational pathology. Fully-supervised models have already achieved outstanding performance with dense pixel-level annotations. However, drawing such labels on the giga-pixel whole…

Image and Video Processing · Electrical Eng. & Systems 2021-10-18 Chu Han , Jiatai Lin , Jinhai Mai , Yi Wang , Qingling Zhang , Bingchao Zhao , Xin Chen , Xipeng Pan , Zhenwei Shi , Xiaowei Xu , Su Yao , Lixu Yan , Huan Lin , Zeyan Xu , Xiaomei Huang , Guoqiang Han , Changhong Liang , Zaiyi Liu

The Segment Anything Model (SAM) has recently emerged as a significant breakthrough in foundation models, demonstrating remarkable zero-shot performance in object segmentation tasks. While SAM is designed for generalization, it exhibits…

Computer Vision and Pattern Recognition · Computer Science 2023-12-15 Josh Stein , Maxime Di Folco , Julia A. Schnabel

Purpose: The Segment Anything Model (SAM) promises to ease the annotation bottleneck in medical segmentation, but overlapping anatomy and blurred boundaries make its point prompts ambiguous, leading to cycles of manual refinement to achieve…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Adrien Meyer , Lorenzo Arboit , Giuseppe Massimiani , Shih-Min Yin , Didier Mutter , Nicolas Padoy

Segmentation is an important analysis task for biomedical images, enabling the study of individual organelles, cells or organs. Deep learning has massively improved segmentation methods, but challenges remain in generalization to new…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Carolin Teuber , Anwai Archit , Constantin Pape

Interactive medical image segmentation (IMIS) has shown significant potential in enhancing segmentation accuracy by integrating iterative feedback from medical professionals. However, the limited availability of enough 3D medical data…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Chuyun Shen , Wenhao Li , Yuhang Shi , Xiangfeng Wang

Learning to segmentation without large-scale samples is an inherent capability of human. Recently, Segment Anything Model (SAM) performs the significant zero-shot image segmentation, attracting considerable attention from the computer…

Image and Video Processing · Electrical Eng. & Systems 2023-12-22 Chuanfei Hu , Tianyi Xia , Shenghong Ju , Xinde Li

Foundation models have taken over natural language processing and image generation domains due to the flexibility of prompting. With the recent introduction of the Segment Anything Model (SAM), this prompt-driven paradigm has entered image…

Image and Video Processing · Electrical Eng. & Systems 2023-04-13 Saikat Roy , Tassilo Wald , Gregor Koehler , Maximilian R. Rokuss , Nico Disch , Julius Holzschuh , David Zimmerer , Klaus H. Maier-Hein

Segmentation of objects of interest is one of the central tasks in medical image analysis, which is indispensable for quantitative analysis. When developing machine-learning based methods for automated segmentation, manual annotations are…

Computer Vision and Pattern Recognition · Computer Science 2020-07-20 Hang Li , Dong Wei , Shilei Cao , Kai Ma , Liansheng Wang , Yefeng Zheng

Traditional supervised medical image segmentation models require large amounts of labeled data for training; however, obtaining such large-scale labeled datasets in the real world is extremely challenging. Recent semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Yunyao Lu , Yihang Wu , Reem Kateb , Ahmad Chaddad

Foundation models like the Segment Anything Model (SAM) excel in zero-shot segmentation for natural images but struggle with medical image segmentation due to differences in texture, contrast, and noise. Annotating medical images is costly…

Image and Video Processing · Electrical Eng. & Systems 2025-04-14 Sourya Sengupta , Satrajit Chakrabarty , Keerthi Sravan Ravi , Gopal Avinash , Ravi Soni

The Segment Anything Model (SAM), originally built on a 2D Vision Transformer (ViT), excels at capturing global patterns in 2D natural images but struggles with 3D medical imaging modalities like CT and MRI. These modalities require…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Xiang Gao , Kai Lu
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