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Many protein design applications, such as binder or enzyme design, require scaffolding a structural motif with high precision. Generative modelling paradigms based on denoising diffusion processes emerged as a leading candidate to address…

Machine Learning · Computer Science 2024-03-15 Kieran Didi , Francisco Vargas , Simon V Mathis , Vincent Dutordoir , Emile Mathieu , Urszula J Komorowska , Pietro Lio

Meta-learning has proven to be successful for few-shot learning across the regression, classification, and reinforcement learning paradigms. Recent approaches have adopted Bayesian interpretations to improve gradient-based meta-learners by…

Machine Learning · Computer Science 2020-12-01 Amrith Setlur , Saket Dingliwal , Barnabas Poczos

Consider a positive random variable of interest Y depending on a covariate X, and a random observation time T independent of Y given X. Assume that the only knowledge available about Y is its current status at time T: \delta = 1_{Y \leq T}.…

Statistics Theory · Mathematics 2013-04-11 Sandra Plancade

Autoregressive conditional duration (ACD) models are primarily used to deal with data arising from times between two successive events. These models are usually specified in terms of a time-varying conditional mean or median duration. In…

Methodology · Statistics 2021-09-10 Helton Saulo , Narayanaswamy Balakrishnan , Roberto Vila

Language diffusion models aim to improve sampling speed and coherence over autoregressive LLMs. We introduce Neural Flow Diffusion Models for language generation, an extension of NFDM that enables the straightforward application of…

Computation and Language · Computer Science 2026-01-26 Nesta Midavaine , Christian A. Naesseth , Grigory Bartosh

Recently, diffusion probabilistic models (DPMs) have achieved promising results in diverse generative tasks. A typical DPM framework includes a forward process that gradually diffuses the data distribution and a reverse process that…

Machine Learning · Computer Science 2023-10-31 Tianyu Pang , Cheng Lu , Chao Du , Min Lin , Shuicheng Yan , Zhijie Deng

Structured additive distributional regression models offer a versatile framework for estimating complete conditional distributions by relating all parameters of a parametric distribution to covariates. Although these models efficiently…

Methodology · Statistics 2023-11-14 Jana Kleinemeier , Nadja Klein

Continuous Conditional Diffusion Model (CCDM) is a diffusion-based framework designed to generate high-quality images conditioned on continuous regression labels. Although CCDM has demonstrated clear advantages over prior approaches across…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Xin Ding , Yun Chen , Sen Zhang , Kao Zhang , Nenglun Chen , Peibei Cao , Yongwei Wang , Fei Wu

Ensemble weather forecasts based on multiple runs of numerical weather prediction models typically show systematic errors and require post-processing to obtain reliable forecasts. Accurately modeling multivariate dependencies is crucial in…

Atmospheric and Oceanic Physics · Physics 2024-02-02 Jieyu Chen , Tim Janke , Florian Steinke , Sebastian Lerch

Given an unconditional diffusion model targeting a joint model $\pi(x, y)$, using it to perform conditional simulation $\pi(x \mid y)$ is still largely an open question and is typically achieved by learning conditional drifts to the…

Machine Learning · Statistics 2025-02-21 Adrien Corenflos , Zheng Zhao , Simo Särkkä , Jens Sjölund , Thomas B. Schön

Diffusion (score-based) generative models have been widely used for modeling various types of complex data, including images, audios, and point clouds. Recently, the deep connection between forward-backward stochastic differential equations…

Machine Learning · Computer Science 2022-06-22 Weitao Du , Tao Yang , He Zhang , Yuanqi Du

Conditional estimation given specific covariate values (i.e., local conditional estimation or functional estimation) is ubiquitously useful with applications in engineering, social and natural sciences. Existing data-driven non-parametric…

Machine Learning · Statistics 2020-10-13 Viet Anh Nguyen , Fan Zhang , Jose Blanchet , Erick Delage , Yinyu Ye

Conditional auto-regressive (CAR) distributions are widely used to induce spatial dependence in the geographic analysis of areal data. These distributions establish multivariate dependence networks by defining conditional relationships…

Methodology · Statistics 2025-07-14 Miguel A. Martinez-Beneito , Aritz Adín , Tomás Goicoa , Lola Ugarte

Score-based diffusion models currently constitute the state of the art in continuous generative modeling. These methods are typically formulated via overdamped or underdamped Ornstein--Uhlenbeck-type stochastic differential equations, in…

Machine Learning · Computer Science 2025-12-22 Herlock Rahimi

Extensive empirical evidence demonstrates that conditional generative models are easier to train and perform better than unconditional ones by exploiting the labels of data. So do score-based diffusion models. In this paper, we analyze the…

Machine Learning · Computer Science 2022-12-02 Fan Bao , Chongxuan Li , Jiacheng Sun , Jun Zhu

Denoising Diffusion Probabilistic Models (DDPM) are powerful state-of-the-art methods used to generate synthetic data from high-dimensional data distributions and are widely used for image, audio, and video generation as well as many more…

Machine Learning · Statistics 2025-04-25 Iskander Azangulov , George Deligiannidis , Judith Rousseau

Conditional expectations given past observations in stationary time series are usually estimated directly by kernel estimators, or by plugging in kernel estimators for transition densities. We show that, for linear and nonlinear…

Statistics Theory · Mathematics 2016-08-14 Ursula U. Müller , Anton Schick , Wolfgang Wefelmeyer

We propose flexible Gaussian representations for conditional cumulative distribution functions and give a concave likelihood criterion for their estimation. Optimal representations satisfy the monotonicity property of conditional cumulative…

Econometrics · Economics 2025-04-22 Richard Spady , Sami Stouli

We consider high-dimensional multivariate linear regression models, where the joint distribution of covariates and response variables is a multivariate normal distribution with a bandable covariance matrix. The main goal of this paper is to…

Statistics Theory · Mathematics 2021-03-12 Kwangmin Lee , Kyoungjae Lee , Jaeyong Lee

We study a discrete denoising diffusion framework that integrates a sample-efficient estimator of single-site conditionals with round-robin noising and denoising dynamics for generative modeling over discrete state spaces. Rather than…

Machine Learning · Computer Science 2026-03-02 Karthik Elamvazhuthi , Abhijith Jayakumar , Andrey Y. Lokhov
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