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We consider a phenotype-switching chemotaxis model for aggregation, in which a chemotactic population is capable of switching back and forth between a chemotaxing state (performing chemotactic movement) and a secreting state (producing the…

Analysis of PDEs · Mathematics 2022-10-11 Kevin J Painter , Michael Winkler

Models for chemotaxis are based on gradient sensing of individual organisms. The key contribution of Keller and Segel is showing that erratic movements of individuals may result in an accurate chemotaxis phenomenon as a group. In this paper…

Populations and Evolution · Quantitative Biology 2013-07-31 Changwook Yoon , Yong-Jung Kim

Chemotaxis in bacteria such as \textit{E.\ coli} is controlled by the slow methylation of chemoreceptors. As a consequence, intrinsic time and length scales of tens of seconds and hundreds of micrometers emerge, making the Keller--Segel…

Soft Condensed Matter · Physics 2025-04-23 Manuel Mayo , Rodrigo Soto

Many phenomena in biology involve both reactions and chemotaxis. These processes can clearly influence each other, and chemotaxis can play an important role in sustaining and speeding up the reaction. In continuation of our earlier work, we…

Analysis of PDEs · Mathematics 2015-06-04 Alexander Kiselev , Lenya Ryzhik

Microorganisms can preferentially orient and move along gradients of a chemo-attractant (i.e., chemotax) while colonies of many microorganisms can collectively undergo complex dynamics in response to chemo-attractants that they themselves…

Biological Physics · Physics 2013-10-30 Enkeleida Lushi , Raymond E. Goldstein , Michael J. Shelley

Chemotaxis receptors in E. coli form clusters at the cell poles and also laterally along the cell body, and this clustering plays an important role in signal transduction. Recently, experiments using flourrescence imaging have shown that,…

Statistical Mechanics · Physics 2008-11-29 Hui Wang , Ned S. Wingreen , Ranjan Mukhopadhyay

Blood vessels form either when dispersed endothelial cells (the cells lining the inner walls of fully-formed blood vessels) organize into a vessel network (vasculogenesis), or by sprouting or splitting of existing blood vessels…

Tissues and Organs · Quantitative Biology 2008-09-24 Roeland M. H. Merks , Erica D. Perryn , Abbas Shirinifard , James A. Glazier

Self-generated gradients have atttracted a lot of attention in the recent biological literature. It is considered as a robust strategy for a group of cells to find its way during a long journey. This note is intended to discuss various…

Analysis of PDEs · Mathematics 2021-09-15 Mete Demircigil , Vincent Calvez , Roxana Sublet

Chemotaxis describes the movement of an organism, such as single or multi-cellular organisms and bacteria, in response to a chemical stimulus. Two widely used models to describe the phenomenon are the celebrated Keller-Segel equation and a…

Analysis of PDEs · Mathematics 2024-01-11 Kathrin Hellmuth , Christian Klingenberg , Qin Li , Min Tang

The collective chemotaxis of multicellular clusters is an important phenomenon in various physiological contexts, ranging from embryonic development to cancer metastasis. Such clusters often display interesting shape dynamics and…

Tissues and Organs · Quantitative Biology 2025-06-03 Monika Sanoria , Gema Malet-Engra , Giorgio Scita , Nir Gov , Ajay Gopinathan

Living systems contain intricate biochemical networks whose structure is closely related to their function and allows them to exhibit robust behavior in the presence of external stimuli. Such networks typically involve catalytic enzymes,…

Biological Physics · Physics 2025-10-27 Vincent Ouazan-Reboul , Ramin Golestanian , Jaime Agudo-Canalejo

Chemotaxis and haptotaxis have been a main theme in the macroscopic study of bacterial and cellular motility. In this work we investigate the influence these processes have on the shape and motility of fast migrating cells. We note that…

Cell Behavior · Quantitative Biology 2016-12-08 Aaron Brunk , Niklas Kolbe , Nikolaos Sfakianakis

A novel mechanism for cell differentiation is proposed, based on the dynamic clustering in a globally coupled chaotic system. A simple model with metabolic reaction, active transport of chemicals from media, and cell division is found to…

adap-org · Physics 2009-10-22 Kunihiko Kaneko , Tetsuya Yomo

We construct a simple model of a proto-cell that simulates a stochastic dynamics of abstract chemicals on a two-dimensional lattice. We assume that chemicals catalyze their reproduction through interaction with each other, and that between…

adap-org · Physics 2007-05-23 Naoaki Ono , Takashi Ikegami

Bacteria can chemotactically migrate up attractant gradients by controlling run-and-tumble motility patterns. In addition to this well-known chemotactic behaviour, several soil and marine bacterial species perform chemokinesis: they adjust…

Biological Physics · Physics 2021-03-19 Theresa Jakuszeit , James Lindsey-Jones , François J. Peaudecerf , Ottavio A. Croze

Advection of entities induced by gradients in attractant concentration fields is observed via diffusiophoresis in colloids and via chemotaxis in microorganisms. Mathematically, both diffusiophoresis and chemotaxis follow similar…

Populations and Evolution · Quantitative Biology 2024-10-07 Benjamin M. Alessio , Ankur Gupta

While the role of local interactions in nonequilibrium phase transitions is well studied, a fundamental understanding of the effects of long-range interactions is lacking. We study the critical dynamics of reproducing agents subject to…

Statistical Mechanics · Physics 2023-08-25 Jasper van der Kolk , Florian Rasshofer , Richard Swiderski , Astik Haldar , Abhik Basu , Erwin Frey

Bacteria are able to respond to environmental signals by changing their rules of movement. When we take into account chemical signals in the environment, this behaviour is often called chemotaxis. At the individual-level, chemotaxis…

Analysis of PDEs · Mathematics 2007-05-23 Radek Erban , Hyung Ju Hwang

We develop the hydrodynamic theory of dry, polar ordered, active matter (``flocking") with autochemotaxis; i.e., self-propelled entities moving in the same direction, each emitting a substance which attracts the others (e.g., ants). We find…

Soft Condensed Matter · Physics 2024-01-22 Maxx Miller , John Toner

Chemotaxis plays a significant role in numerous physiological processes. The Keller-Segel equation serves as a mathematical model for simulating the phenomenon of cell population aggregation under chemotaxis, possessing physical properties…

Numerical Analysis · Mathematics 2025-02-24 Mingmei Chen , Kun Wang , Cong Xie