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We focus on the problem of efficient sampling and learning of probability densities by incorporating symmetries in probabilistic models. We first introduce Equivariant Stein Variational Gradient Descent algorithm -- an equivariant sampling…

Machine Learning · Computer Science 2021-07-30 Priyank Jaini , Lars Holdijk , Max Welling

Large-scale atomistic computer simulations of materials heavily rely on interatomic potentials predicting the potential energy and Newtonian forces on atoms. Traditional interatomic potentials are based on physical intuition but contain few…

Materials Science · Physics 2019-06-11 G. P. Purja Pun , R. Batra , R. Ramprasad , Y. Mishin

Given Spatial Variability Aware Neural Networks (SVANNs), the goal is to investigate mathematical (or computational) models for comparative physical interpretation towards their transparency (e.g., simulatibility, decomposability and…

Machine Learning · Computer Science 2021-11-01 Jayant Gupta , Carl Molnar , Gaoxiang Luo , Joe Knight , Shashi Shekhar

Equivariant Graph Neural Networks (eGNNs) trained on density-functional theory (DFT) data can potentially perform electronic structure prediction at unprecedented scales, enabling investigation of the electronic properties of materials with…

Machine Learning · Computer Science 2025-07-08 Manasa Kaniselvan , Alexander Maeder , Chen Hao Xia , Alexandros Nikolaos Ziogas , Mathieu Luisier

Recent work has shown the utility of developing machine learning models that respect the structure and symmetries of eigenvectors. These works promote sign invariance, since for any eigenvector v the negation -v is also an eigenvector.…

Machine Learning · Computer Science 2023-12-06 Derek Lim , Joshua Robinson , Stefanie Jegelka , Haggai Maron

Predicting structural and energetic properties of a molecular system is one of the fundamental tasks in molecular simulations, and it has use cases in chemistry, biology, and medicine. In the past decade, the advent of machine learning…

Chemical Physics · Physics 2022-08-23 Sajjad Heydari , Stefano Raniolo , Lorenzo Livi , Vittorio Limongelli

We refine the OrbNet model to accurately predict energy, forces, and other response properties for molecules using a graph neural-network architecture based on features from low-cost approximated quantum operators in the symmetry-adapted…

The usage of 3D vision algorithms, such as shape reconstruction, remains limited because they require inputs to be at a fixed canonical rotation. Recently, a simple equivariant network, Vector Neuron (VN) has been proposed that can be…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Dongwon Son , Jaehyung Kim , Sanghyeon Son , Beomjoon Kim

Incorporating inductive biases into ML models is an active area of ML research, especially when ML models are applied to data about the physical world. Equivariant Graph Neural Networks (GNNs) have recently become a popular method for…

Machine Learning · Computer Science 2023-11-07 Savannah Thais , Daniel Murnane

Accurate simulations of molecules require high-level electronic-structure theory in combination with rigorous methods for approximating the quantum dynamics. Machine-learning approaches can significantly reduce the computational expense of…

Chemical Physics · Physics 2026-02-24 Valerii Andreichev , Jindra Dušek , Markus Meuwly , Jeremy O. Richardson

Simulations of chemical reaction probabilities in gas surface dynamics require the calculation of ensemble averages over many tens of thousands of reaction events to predict dynamical observables that can be compared to experiments. At the…

Rotation equivariance is a desirable property in many practical applications such as motion forecasting and 3D perception, where it can offer benefits like sample efficiency, better generalization, and robustness to input perturbations.…

Computer Vision and Pattern Recognition · Computer Science 2023-01-26 Serge Assaad , Carlton Downey , Rami Al-Rfou , Nigamaa Nayakanti , Ben Sapp

Group equivariance (e.g. SE(3) equivariance) is a critical physical symmetry in science, from classical and quantum physics to computational biology. It enables robust and accurate prediction under arbitrary reference transformations. In…

Computational Engineering, Finance, and Science · Computer Science 2023-02-08 Weitao Du , He Zhang , Yuanqi Du , Qi Meng , Wei Chen , Bin Shao , Tie-Yan Liu

Machine-learning interatomic potentials (MLIPs) have enabled molecular dynamics at near ab initio accuracy, yet remain limited to energies and forces by construction, leaving electronic observables such as dipole moments and…

Structure-informed protein representation learning is essential for effective protein function annotation and \textit{de novo} design. However, the presence of inherent noise in both crystal and AlphaFold-predicted structures poses…

Biomolecules · Quantitative Biology 2025-03-25 Zhongyue Zhang , Runze Ma , Yanjie Huang , Shuangjia Zheng

Learning representations for structured data with certain geometries (e.g., observed or unobserved) is a fundamental challenge, wherein message passing neural networks (MPNNs) have become a de facto class of model solutions. In this paper,…

Machine Learning · Computer Science 2025-07-02 Qitian Wu , David Wipf , Junchi Yan

In this work we investigate how to achieve equivariance to input transformations in deep networks, purely from data, without being given a model of those transformations. Convolutional Neural Networks (CNNs), for example, are equivariant to…

Computer Vision and Pattern Recognition · Computer Science 2021-11-29 Jianbo Jiao , João F. Henriques

Building effective imitation learning methods that enable robots to learn from limited data and still generalize across diverse real-world environments is a long-standing problem in robot learning. We propose Equibot, a robust,…

Robotics · Computer Science 2024-10-30 Jingyun Yang , Zi-ang Cao , Congyue Deng , Rika Antonova , Shuran Song , Jeannette Bohg

Recently, Koopman operator theory has become a powerful tool for developing linear representations of non-linear dynamical systems. However, existing data-driven applications of Koopman operator theory, including both traditional and deep…

Machine Learning · Computer Science 2023-05-17 King Fai Yeh , Paris Flood , William Redman , Pietro Liò

Machine learning has transformed the field of atomistic simulations by enabling the development of interatomic potentials that are computationally efficient and highly accurate. These advances have opened the door to modeling molecular…

Chemical Physics · Physics 2026-05-22 Nitik Bhatia , Ondrej Krejci , Patrick Rinke