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The emerging scale segmentation model, Segment Anything (SAM), exhibits impressive capabilities in zero-shot segmentation for natural images. However, when applied to medical images, SAM suffers from noticeable performance drop. To make SAM…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Xinrong Hu , Xiaowei Xu , Yiyu Shi

Foundation models (FMs) such as CLIP and SAM have recently shown great promise in image segmentation tasks, yet their adaptation to 3D medical imaging-particularly for pathology detection and segmentation-remains underexplored. A critical…

Image and Video Processing · Electrical Eng. & Systems 2025-08-28 Sirui Li , Linkai Peng , Zheyuan Zhang , Gorkem Durak , Ulas Bagci

The landscape of publicly available vision foundation models (VFMs), such as CLIP and Segment Anything Model (SAM), is expanding rapidly. VFMs are endowed with distinct capabilities stemming from their pre-training objectives. For instance,…

Zero-shot medical image classification is a critical process in real-world scenarios where we have limited access to all possible diseases or large-scale annotated data. It involves computing similarity scores between a query medical image…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Jiaxiang Liu , Tianxiang Hu , Yan Zhang , Xiaotang Gai , Yang Feng , Zuozhu Liu

We have witnessed remarkable progress in foundation models in vision tasks. Currently, several recent works have utilized the segmenting anything model (SAM) to boost the segmentation performance in medical images, where most of them focus…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Haoran Wang , Lian Huai , Wenbin Li , Lei Qi , Xingqun Jiang , Yinghuan Shi

Learning to segmentation without large-scale samples is an inherent capability of human. Recently, Segment Anything Model (SAM) performs the significant zero-shot image segmentation, attracting considerable attention from the computer…

Image and Video Processing · Electrical Eng. & Systems 2023-12-22 Chuanfei Hu , Tianyi Xia , Shenghong Ju , Xinde Li

Surgical video segmentation is a critical task in computer-assisted surgery and is vital for enhancing surgical quality and patient outcomes. Recently, the Segment Anything Model 2 (SAM2) framework has shown superior advancements in image…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Haofeng Liu , Erli Zhang , Junde Wu , Mingxuan Hong , Yueming Jin

Segmentation models such as Segment Anything Model (SAM) and SAM2 achieve strong prompt-driven zero-shot performance. However, their training on natural images limits domain transfer to medical data. Consequently, accurate segmentation…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Tal Grossman , Noa Cahan , Lev Ayzenberg , Hayit Greenspan

Medical image segmentation has advanced rapidly over the past two decades, largely driven by deep learning, which has enabled accurate and efficient delineation of cells, tissues, organs, and pathologies across diverse imaging modalities.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Guoping Xu , Jayaram K. Udupa , Jax Luo , Songlin Zhao , Yajun Yu , Scott B. Raymond , Hao Peng , Lipeng Ning , Yogesh Rathi , Wei Liu , You Zhang

Meta recently released SAM (Segment Anything Model) which is a general-purpose segmentation model. SAM has shown promising results in a wide variety of segmentation tasks including medical image segmentation. In the field of medical image…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Risab Biswas

Large foundation models, known for their strong zero-shot generalization capabilities, can be applied to a wide range of downstream tasks. However, developing foundation models for medical image segmentation poses a significant challenge…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Sihan Yang , Jiadong Feng , Xuande Mi , Haixia Bi , Hai Zhang , Jian Sun

Most medical image lesion segmentation methods rely on hand-crafted accurate annotations of the original image for supervised learning. Recently, a series of weakly supervised or unsupervised methods have been proposed to reduce the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Jiawei Chen , Dingkang Yang , Yuxuan Lei , Lihua Zhang

The Segment Anything Model (SAM) made an eye-catching debut recently and inspired many researchers to explore its potential and limitation in terms of zero-shot generalization capability. As the first promptable foundation model for…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Dongjie Cheng , Ziyuan Qin , Zekun Jiang , Shaoting Zhang , Qicheng Lao , Kang Li

Weakly supervised semantic segmentation (WSSS) with image-level labels is a challenging task. Mainstream approaches follow a multi-stage framework and suffer from high training costs. In this paper, we explore the potential of Contrastive…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Yuqi Lin , Minghao Chen , Wenxiao Wang , Boxi Wu , Ke Li , Binbin Lin , Haifeng Liu , Xiaofei He

Following the successful paradigm shift of large language models, leveraging pre-training on a massive corpus of data and fine-tuning on different downstream tasks, generalist models have made their foray into computer vision. The…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Andrea Moglia , Matteo Leccardi , Matteo Cavicchioli , Alice Maccarini , Marco Marcon , Luca Mainardi , Pietro Cerveri

Medical image processing usually requires a model trained with carefully crafted datasets due to unique image characteristics and domain-specific challenges, especially in pathology. Primitive detection and segmentation in digitized tissue…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Abu Bakor Hayat Arnob , Xiangxue Wang , Yiping Jiao , Xiao Gan , Wenlong Ming , Jun Xu

The universality of deep neural networks across different modalities and their generalization capabilities to unseen domains play an essential role in medical image segmentation. The recent segment anything model (SAM) has demonstrated…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Qing Xu , Jiaxuan Li , Xiangjian He , Chenxin Li , Fiseha B. Tesem , Wenting Duan , Zhen Chen , Rong Qu , Jonathan M. Garibaldi , Chang Wen Chen

Medical image segmentation has immense clinical applicability but remains a challenge despite advancements in deep learning. The Segment Anything Model (SAM) exhibits potential in this field, yet the requirement for expertise intervention…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Yinsong Xu , Jiaqi Tang , Aidong Men , Qingchao Chen

Segment Anything Model 2 (SAM2) demonstrated impressive zero-shot capabilities on natural images but faces challenges in biomedical segmentation due to significant domain shifts and prompt dependency. To address these limitations, we…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Hinako Mitsuoka , Kazuhiro Hotta

Image segmentation plays an essential role in medicine for both diagnostic and interventional tasks. Segmentation approaches are either manual, semi-automated or fully-automated. Manual segmentation offers full control over the quality of…

Computer Vision and Pattern Recognition · Computer Science 2019-03-21 Tomas Sakinis , Fausto Milletari , Holger Roth , Panagiotis Korfiatis , Petro Kostandy , Kenneth Philbrick , Zeynettin Akkus , Ziyue Xu , Daguang Xu , Bradley J. Erickson
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