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This paper explores the use of self-supervised deep learning in medical imaging in cases where two scan modalities are available for the same subject. Specifically, we use a large publicly-available dataset of over 20,000 subjects from the…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Rhydian Windsor , Amir Jamaludin , Timor Kadir , Andrew Zisserman

In this paper we propose a novel method for the segmentation of longitudinal brain MRI scans of patients suffering from Multiple Sclerosis. The method builds upon an existing cross-sectional method for simultaneous whole-brain and lesion…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Stefano Cerri , Andrew Hoopes , Douglas N. Greve , Mark Mühlau , Koen Van Leemput

Deep learning has revolutionized biomedical research by providing sophisticated methods to handle complex, high-dimensional data. Multimodal deep learning (MDL) further enhances this capability by integrating diverse data types such as…

Machine Learning · Computer Science 2026-03-13 Valerio Guarrasi , Fatih Aksu , Camillo Maria Caruso , Francesco Di Feola , Aurora Rofena , Filippo Ruffini , Paolo Soda

Self-supervised learning is an efficient pre-training method for medical image analysis. However, current research is mostly confined to specific-modality data pre-training, consuming considerable time and resources without achieving…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Yiwen Ye , Yutong Xie , Jianpeng Zhang , Ziyang Chen , Qi Wu , Yong Xia

Multimodal (MM) learning is emerging as a promising paradigm in biomedical artificial intelligence (AI) applications, integrating complementary modality, which highlight different aspects of patient health. The scarcity of large…

Artificial Intelligence · Computer Science 2025-12-01 Niccolo Marini , Zhaohui Liang , Sivaramakrishnan Rajaraman , Zhiyun Xue , Sameer Antani

Deep learning models such as convolutional neural net- work have been widely used in 3D biomedical segmentation and achieve state-of-the-art performance. However, most of them often adapt a single modality or stack multiple modalities as…

Computer Vision and Pattern Recognition · Computer Science 2017-04-26 Kuan-Lun Tseng , Yen-Liang Lin , Winston Hsu , Chung-Yang Huang

Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central nervous system, characterized by the appearance of focal lesions in the white and gray matter that topographically correlate with an individual…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Yang Ma , Chaoyi Zhang , Mariano Cabezas , Yang Song , Zihao Tang , Dongnan Liu , Weidong Cai , Michael Barnett , Chenyu Wang

Synthesizing missing modalities in multi-modal magnetic resonance imaging (MRI) is vital for ensuring diagnostic completeness, particularly when full acquisitions are infeasible due to time constraints, motion artifacts, and patient…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yue Zhang , Zhizheng Zhuo , Siyao Xu , Shan Lv , Zhaoxi Liu , Jun Qiu , Qiuli Wang , Yaou Liu , S. Kevin Zhou

Multimodal MRI offers complementary multi-scale information to characterize the brain structure. However, it remains challenging to effectively integrate multimodal MRI while achieving neuroscience interpretability. Here we propose to use…

Neurons and Cognition · Quantitative Biology 2025-12-15 Chengzhi Xia , Jianwei Chen , Yixuan Jiang , Qi Yan , Chao Li

In recent years, multi-modal fusion has attracted a lot of research interest, both in academia, and in industry. Multimodal fusion entails the combination of information from a set of different types of sensors. Exploiting complementary…

Machine Learning · Computer Science 2020-08-27 Siddharth Roheda , Hamid Krim , Benjamin S. Riggan

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Magnetic resonance imaging (MRI) is extensively used for diagnosis and image-guided therapeutics. Due to hardware, physical and physiological limitations, acquisition of high-resolution MRI data takes long scan time at high system cost, and…

Medical Physics · Physics 2018-10-17 Qing Lyu , Chenyu You , Hongming Shan , Ge Wang

Leveraging multimodal information from Magnetic Resonance Imaging (MRI) plays a vital role in lesion segmentation, especially for brain tumors. However, in clinical practice, multimodal MRI data are often incomplete, making it challenging…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Yulong Zou , Bo Liu , Cun-Jing Zheng , Yuan-ming Geng , Siyue Li , Qiankun Zuo , Shuihua Wang , Yudong Zhang , Jin Hong

We propose a fluid-based registration framework of medical images based on implicit neural representation. By integrating implicit neural representation and Large Deformable Diffeomorphic Metric Mapping (LDDMM), we employ a Multilayer…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Chulong Zhang , Xiaokun Liang

In recent years, there has been a significant increase in applications of multimodal signal processing and analysis, largely driven by the increased availability of multimodal datasets and the rapid progress in multimodal learning systems.…

Image and Video Processing · Electrical Eng. & Systems 2024-05-22 Hadi Hadizadeh , S. Faegheh Yeganli , Bahador Rashidi , Ivan V. Bajić

Multi-modality image fusion and segmentation play a vital role in autonomous driving and robotic operation. Early efforts focus on boosting the performance for only one task, \emph{e.g.,} fusion or segmentation, making it hard to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-07 Jinyuan Liu , Zhu Liu , Guanyao Wu , Long Ma , Risheng Liu , Wei Zhong , Zhongxuan Luo , Xin Fan

Multi-modal Magnetic Resonance Imaging (MRI) translation leverages information from source MRI sequences to generate target modalities, enabling comprehensive diagnosis while overcoming the limitations of acquiring all sequences. While…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Jiyao Liu , Shangqi Gao , Yuxin Li , Lihao Liu , Xin Gao , Zhaohu Xing , Junzhi Ning , Yanzhou Su , Xiao-Yong Zhang , Junjun He , Ningsheng Xu , Xiahai Zhuang

Clinical decision making from magnetic resonance imaging (MRI) combines complementary information from multiple MRI sequences (defined as 'modalities'). MRI image registration aims to geometrically 'pair' diagnoses from different…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Chengjia Wang , Giorgos Papanastasiou

Although diffusion models have achieved remarkable progress in multi-modal magnetic resonance imaging (MRI) translation tasks, existing methods still tend to suffer from anatomical inconsistencies or degraded texture details when handling…

Image and Video Processing · Electrical Eng. & Systems 2026-03-16 Jianqiang Lin , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane , Xiaoli Liu

With the advancement of artificial intelligence and computer vision technologies, multimodal emotion recognition has become a prominent research topic. However, existing methods face challenges such as heterogeneous data fusion and the…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Wei Dai , Dequan Zheng , Feng Yu , Yanrong Zhang , Yaohui Hou