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The proliferation of LLM-based conversational agents has resulted in excessive disclosure of identifiable or sensitive information. However, existing technologies fail to offer perceptible control or account for users' personal preferences…

Human-Computer Interaction · Computer Science 2025-02-13 Jijie Zhou , Eryue Xu , Yaoyao Wu , Tianshi Li

Clinical decision-making is inherently complex and fast-paced, particularly in emergency departments (EDs) where critical, rapid and high-stakes decisions are made. Clinical Decision Rules (CDRs) are standardized evidence-based tools that…

Scientific research indicates that for every hour spent in direct patient care, physicians spend nearly two additional hours on administrative tasks, particularly on electronic health records (EHRs) and desk work. This excessive…

Computation and Language · Computer Science 2025-09-25 Hui Yi Leong , Yi Fan Gao , Ji Shuai , Yang Zhang , Uktu Pamuksuz

Standardized, validated questionnaires are vital tools in research and healthcare, offering dependable self-report data. Prior work has revealed that virtual agent-administered questionnaires are almost equivalent to self-administered ones…

Human-Computer Interaction · Computer Science 2024-07-09 Hye Sun Yun , Mehdi Arjmand , Phillip Sherlock , Michael K. Paasche-Orlow , James W. Griffith , Timothy Bickmore

The incidence rate of early-onset colorectal cancer (EoCRC, age < 45) has increased every year, but this population is younger than the recommended age established by national guidelines for cancer screening. In this paper, we applied 10…

Computation and Language · Computer Science 2025-06-16 Wilson Lau , Youngwon Kim , Sravanthi Parasa , Md Enamul Haque , Anand Oka , Jay Nanduri

Given the impact of health literacy (HL) on patients outcomes, limited health literacy (LHL) is a major barrier in cancer care globally. HL refers to the degree in which an individual is able to acquire, process and comprehend information…

Human-Computer Interaction · Computer Science 2022-01-24 Hajar Hasannejadasl , Cheryl Roumen , Yolba Smit , Andre Dekker , Rianne Fijten

Patient matching is the process of linking patients to appropriate clinical trials by accurately identifying and matching their medical records with trial eligibility criteria. We propose LLM-Match, a novel framework for patient matching…

Computation and Language · Computer Science 2025-03-26 Xiaodi Li , Shaika Chowdhury , Chung Il Wi , Maria Vassilaki , Xiaoke Liu , Terence T Sio , Owen Garrick , Young J Juhn , James R Cerhan , Cui Tao , Nansu Zong

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

Rapid integration of large language models (LLMs) in health care is sparking global discussion about their potential to revolutionize health care quality and accessibility. At a time when improving health care quality and access remains a…

Computers and Society · Computer Science 2025-04-01 Troy Zada , Natalie Tam , Francois Barnard , Marlize Van Sittert , Venkat Bhat , Sirisha Rambhatla

Large language models (LLMs) enable conversational agents (CAs) to express distinctive personalities, raising new questions about how such designs shape user perceptions. This study investigates how personality expression levels and…

Human-Computer Interaction · Computer Science 2026-04-30 Hasibur Rahman , Smit Desai

Large Language Models (LLMs) are increasingly deployed in mental health contexts, from structured therapeutic support tools to informal chat-based well-being assistants. While these systems increase accessibility, scalability, and…

Human-Computer Interaction · Computer Science 2025-10-14 Soraya S. Anvari , Rina R. Wehbe

Millions of individuals' well-being are challenged by the harms of substance use. Harm reduction as a public health strategy is designed to improve their health outcomes and reduce safety risks. Some large language models (LLMs) have…

Computation and Language · Computer Science 2025-07-30 Kaixuan Wang , Chenxin Diao , Jason T. Jacques , Zhongliang Guo , Shuai Zhao

Background: We present a Patient Simulator that leverages real world patient encounters which cover a broad range of conditions and symptoms to provide synthetic test subjects for development and testing of healthcare agentic models. The…

Computation and Language · Computer Science 2025-06-05 Sina Rashidian , Nan Li , Jonathan Amar , Jong Ha Lee , Sam Pugh , Eric Yang , Geoff Masterson , Myoung Cha , Yugang Jia , Akhil Vaid

Personalized learning represents a promising educational strategy within intelligent educational systems, aiming to enhance learners' practice efficiency. However, the discrepancy between offline metrics and online performance significantly…

Computers and Society · Computer Science 2026-05-29 Weibo Gao , Qi Liu , Linan Yue , Fangzhou Yao , Rui Lv , Zheng Zhang , Hao Wang , Zhenya Huang

Large Language Model (LLM) agents are increasingly utilized in AI-aided education to support tutoring and learning. Effective communication strategies among LLM agents improve collaborative problem-solving efficiency and facilitate…

Web agents have emerged as a promising direction to automate Web task completion based on user instructions, significantly enhancing user experience. Recently, Web agents have evolved from traditional agents to Large Language Models…

Computation and Language · Computer Science 2025-03-25 Hongru Cai , Yongqi Li , Wenjie Wang , Fengbin Zhu , Xiaoyu Shen , Wenjie Li , Tat-Seng Chua

Digital health analytics face critical challenges nowadays. The sophisticated analysis of patient-generated health content, which contains complex emotional and medical contexts, requires scarce domain expertise, while traditional ML…

The development of large language models (LLMs) has brought unprecedented possibilities for artificial intelligence (AI) based medical diagnosis. However, the application perspective of LLMs in real diagnostic scenarios is still unclear…

Computation and Language · Computer Science 2024-05-21 Zhoujian Sun , Cheng Luo , Ziyi Liu , Zhengxing Huang

Recent studies have uncovered the potential of Large Language Models (LLMs) in addressing complex sequential decision-making tasks through the provision of high-level instructions. However, LLM-based agents lack specialization in tackling…

Artificial Intelligence · Computer Science 2024-05-28 Zihao Zhou , Bin Hu , Chenyang Zhao , Pu Zhang , Bin Liu

Cognitive behavioral therapy (CBT) is a widely used therapeutic method for guiding individuals toward restructuring their thinking patterns as a means of addressing anxiety, depression, and other challenges. We developed a large language…