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The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

This paper presents a novel application of large language models (LLMs) to enhance user comprehension of privacy policies through an interactive dialogue agent. We demonstrate that LLMs significantly outperform traditional models in tasks…

Human-Computer Interaction · Computer Science 2024-10-17 Bolun Sun , Yifan Zhou , Haiyun Jiang

EduChat (https://www.educhat.top/) is a large-scale language model (LLM)-based chatbot system in the education domain. Its goal is to support personalized, fair, and compassionate intelligent education, serving teachers, students, and…

Computation and Language · Computer Science 2023-08-08 Yuhao Dan , Zhikai Lei , Yiyang Gu , Yong Li , Jianghao Yin , Jiaju Lin , Linhao Ye , Zhiyan Tie , Yougen Zhou , Yilei Wang , Aimin Zhou , Ze Zhou , Qin Chen , Jie Zhou , Liang He , Xipeng Qiu

Many people struggle with learning a new language, with traditional tools falling short in providing contextualized learning tailored to each learner's needs. The recent development of large language models (LLMs) and embodied…

Human-Computer Interaction · Computer Science 2024-10-04 Mengxu Pan , Alexandra Kitson , Hongyu Wan , Mirjana Prpa

Online health resources and large language models (LLMs) are increasingly used as a first point of contact for medical decision-making, yet their reliability in healthcare remains limited by low accuracy, lack of transparency, and…

Artificial Intelligence · Computer Science 2026-04-22 Yujia Liu , Sophia Yu , Hongyue Jin , Jessica Wen , Alexander Qian , Terrence Lee , Mattheus Ramsis , Gi Won Choi , Lianhui Qin , Xin Liu , Edward J. Wang

Electronic health records (EHRs) contain valuable patient data for health-related prediction tasks, such as disease prediction. Traditional approaches rely on supervised learning methods that require large labeled datasets, which can be…

Computation and Language · Computer Science 2024-03-26 Hejie Cui , Zhuocheng Shen , Jieyu Zhang , Hui Shao , Lianhui Qin , Joyce C. Ho , Carl Yang

Large language model (LLM) chatbots show increasing promise in persuasive communication. Yet their real-world utility remains uncertain, particularly in clinical settings where sustained conversations are difficult to scale. In a…

Large language models (LLMs) have facilitated significant strides in generating conversational agents, enabling seamless, contextually relevant dialogues across diverse topics. However, the existing LLM-driven conversational agents have…

Human-Computer Interaction · Computer Science 2024-02-26 Juhye Ha , Hyeon Jeon , DaEun Han , Jinwook Seo , Changhoon Oh

In response to the increasing mental health challenges faced by college students, we sought to understand their perspectives on how AI applications, particularly Large Language Models (LLMs), can be leveraged to enhance their mental…

Human-Computer Interaction · Computer Science 2024-09-27 Owen Xingjian Zhang , Shuyao Zhou , Jiayi Geng , Yuhan Liu , Sunny Xun Liu

Training medical personnel using standardized patients (SPs) remains a complex challenge, requiring extensive domain expertise and role-specific practice. Previous research on Large Language Model (LLM)-based SPs mostly focuses on improving…

Computation and Language · Computer Science 2025-06-10 Zhuoyun Du , Lujie Zheng , Renjun Hu , Yuyang Xu , Xiawei Li , Ying Sun , Wei Chen , Jian Wu , Haolei Cai , Haohao Ying

Training mental health clinicians to conduct standardized clinical assessments is challenging due to a lack of scalable, realistic practice opportunities, which can impact data quality in clinical trials. To address this gap, we introduce a…

Human-Computer Interaction · Computer Science 2025-12-30 Veronica Bossio Botero , Vijay Yadav , Jacob Ouyang , Anzar Abbas , Michelle Worthington

Recent advances in large language models (LLMs) have shown promising results in medical diagnosis, with some studies indicating superior performance compared to human physicians in specific scenarios. However, the diagnostic capabilities of…

Artificial Intelligence · Computer Science 2025-03-24 Zhoujian Sun , Ziyi Liu , Cheng Luo , Jiebin Chu , Zhengxing Huang

Although engagement in self-directed wellness exercises typically declines over time, integrating social support such as coaching can sustain it. However, traditional forms of support are often inaccessible due to the high costs and complex…

Discharge communication is a critical yet underexplored component of patient care, where the goal shifts from diagnosis to education. While recent large language model (LLM) benchmarks emphasize in-visit diagnostic reasoning, they fail to…

Computation and Language · Computer Science 2025-09-22 Zonghai Yao , Michael Sun , Won Seok Jang , Sunjae Kwon , Soie Kwon , Hong Yu

Recent large language models (LLMs) have demonstrated significant advancements, particularly in their ability to serve as agents thereby surpassing their traditional role as chatbots. These agents can leverage their planning and tool…

Machine Learning · Computer Science 2025-02-13 Yixing Jiang , Kameron C. Black , Gloria Geng , Danny Park , James Zou , Andrew Y. Ng , Jonathan H. Chen

Large language models have shown success as a tutor in education in various fields. Educating patients about their clinical visits plays a pivotal role in patients' adherence to their treatment plans post-discharge. This paper presents…

Computation and Language · Computer Science 2023-10-31 Zihao Zhang , Zonghai Yao , Huixue Zhou , Feiyun ouyang , Hong Yu

Background: Simulated patient systems are important in medical education and research, providing safe, integrative training environments and supporting clinical decision making. Advances in artificial intelligence (AI), especially large…

The integration of deep learning-based glaucoma detection with large language models (LLMs) presents an automated strategy to mitigate ophthalmologist shortages and improve clinical reporting efficiency. However, applying general LLMs to…

Multiagent Systems · Computer Science 2025-12-18 Philip R. Liu , Sparsh Bansal , Jimmy Dinh , Aditya Pawar , Ramani Satishkumar , Shail Desai , Neeraj Gupta , Xin Wang , Shu Hu

Cancer clinical trials often face challenges in recruitment and engagement due to a lack of participant-facing informational and educational resources. This study investigated the potential of Large Language Models (LLMs), specifically…

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