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Mathematical models and numerical simulations offer a non-invasive way to explore cardiovascular phenomena, providing access to quantities that cannot be measured directly. In this study, we start with a one-dimensional multiscale blood…

Machine Learning · Computer Science 2026-04-09 Giulia Bertaglia , Raffaella Fiamma Cabini

This paper introduces a new method for estimating the penetration of the end effector and the parameters of a soft body using a collaborative robotic arm. This is possible using the dimensionality reduction method that simplifies the…

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

We propose a novel autonomous robotic palpation framework for real-time elastic mapping during tissue exploration using a viscoelastic tissue model. The method combines force-based parameter estimation using a commercial force/torque sensor…

Robotics · Computer Science 2026-02-17 Luca Beber , Edoardo Lamon , Matteo Saveriano , Daniele Fontanelli , Luigi Palopoli

Atrioventricular valve regurgitation is a significant cause of morbidity and mortality in patients with acquired and congenital cardiac valve disease. Image-derived computational modeling of atrioventricular valves has advanced…

Tissues and Organs · Quantitative Biology 2022-02-01 Wensi Wu , Stephen Ching , Steve A. Maas , Andras Lasso , Patricia Sabin , Jeffrey A. Weiss , Matthew A. Jolley

Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…

Numerical Analysis · Mathematics 2024-11-28 Kabir Bakhshaei , Sajad Salavatidezfouli , Giovanni Stabile , Gianluigi Rozza

Valvular heart diseases are growing concern in impoverished parts of the world, such as Southern-Africa, claiming more than 31 % of total deaths related to cardiovascular diseases. The ability to model the effects of regurgitant and…

Medical Physics · Physics 2022-04-11 Ryno Laubscher , Jacques Liebenberg , Philip Herbst

X-ray Computed Tomography (CT) is used to recover the true surfaces of fluid channels and fed to simulation tool (ANSYS) to create accurate cyber environment. The simulation tool also receives CT-assisted multiphase fluid profiles…

Fluid Dynamics · Physics 2024-08-06 Vaishali Sharma , Arpit Kumar , Snehlata Shakya , Mayank Goswami

This work deals with the viscoelasticity of the arterial wall and its influence on the pulse waves. We describe the viscoelasticity by a non-linear Kelvin-Voigt model in which the coefficients are fitted using experimental time series of…

Biological Physics · Physics 2016-07-28 Arthur Ghigo , Xiao-Fei Wang , Ricardo Armentano , Pierre-Yves Lagrée , Jose-Maria Fullana

An automatic elastic registration method suited for vascularized organs is proposed. The vasculature in both the preoperative and intra-operative images is represented as a graph. A typical application of this method is the fusion of…

Computer Vision and Pattern Recognition · Computer Science 2019-12-16 Jaime Garcia Guevara , Igor Peterlik , Marie-Odile Berger , Stéphane Cotin

Purpose: The mechanics of the mitral valve leaflet as a nonlinear, inelastic and anisotropic soft tissue results from an integrated response of many mathematical/physical indexes' that illustrate the tissue. In the past decade, finite…

Medical Physics · Physics 2015-06-24 Mersedeh Karvandi , Saeed Ranjbar , Seyed Ahmad Hassantash , Mahnoosh Foroughi

In this paper we introduce a new method simulating stent graft deployment for assisting endovascular repair of abdominal aortic aneurysms. The method relies on intraoperative images coupled with mechanical models. A multi-step algorithm has…

To date, the simulation of organ deformations for applications like therapy planning or image-guided interventions is calculated by solving the elastodynamics equations. While efficient solvers have been proposed for fast simulations,…

Quantitative Methods · Quantitative Biology 2018-12-18 Felix Meister , Tiziano Passerini , Viorel Mihalef , Ahmet Tuysuzoglu , Andreas Maier , Tommaso Mansi

The paper presents an approach for the identification of elasto-static parameters of a robotic manipulator using the virtual experiments in a CAD environment. It is based on the numerical processing of the data extracted from the finite…

Robotics · Computer Science 2013-11-27 Alexandr Klimchik , Anatol Pashkevich , Damien Chablat

This paper presents an elastic-viscoplastic (EVP) constitutive model in triaxial space and general stress space for isotropic clays. The EVP model is anchored in the bounding surface theory along with the mapping rule and adopts a critical…

Geophysics · Physics 2018-01-08 M. N. Islam , C. T. Gnanendran

We introduce an innovative lumped-parameter model of the aortic valve, designed to efficiently simulate the impact of valve dynamics on blood flow. Our reduced model includes the elastic effects associated with the leaflets' curvature and…

Numerical Analysis · Mathematics 2025-04-15 Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

Due to the computationally demanding nature of fluid-structure interaction simulations, heart valve simulation is a complex task. A simpler alternative is to model the valve as a resistive flow obstacle that can be updated dynamically…

Tissues and Organs · Quantitative Biology 2025-12-12 Bob van der Vuurst , Jiří Kosinka , Cristóbal Bertoglio

A central problem in biomechanical studies of personalised human left ventricular (LV) modelling is estimating the material properties and biophysical parameters from in-vivo clinical measurements in a time frame suitable for use within a…

Applications · Statistics 2019-05-16 Vinny Davies , Umberto Noè , Alan Lazarus , Hao Gao , Benn Macdonald , Colin Berry , Xiaoyu Luo , Dirk Husmeier

Investigating blood flow in the cardiovascular system is crucial for assessing cardiovascular health. Computational approaches offer some non-invasive alternatives to measure blood flow dynamics. Numerical simulations based on traditional…

Numerical Analysis · Mathematics 2024-06-07 Han Zhang , Raymond Chan , Xue-Cheng Tai

Patient-specific computational modeling of the tricuspid valve (TV) is vital for the clinical assessment of heart valve diseases. However, this process is hindered by limitations inherent in the medical image data, such as noise and…

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