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We propose a virtual staining methodology based on Generative Adversarial Networks to map histopathology images of breast cancer tissue from H&E stain to PHH3 and vice versa. We use the resulting synthetic images to build Convolutional…

Image and Video Processing · Electrical Eng. & Systems 2020-03-18 Caner Mercan , Germonda Reijnen-Mooij , David Tellez Martin , Johannes Lotz , Nick Weiss , Marcel van Gerven , Francesco Ciompi

Clinicians compare breast DCE-MRI after neoadjuvant chemotherapy (NAC) with pre-treatment scans to evaluate the response to NAC. Clinical evidence supports that accurate longitudinal deformable registration without deforming treated tumor…

Image and Video Processing · Electrical Eng. & Systems 2024-01-18 Luyi Han , Tao Tan , Tianyu Zhang , Yuan Gao , Xin Wang , Valentina Longo , Sofía Ventura-Díaz , Anna D'Angelo , Jonas Teuwen , Ritse Mann

Automated breast tumor segmentation on the basis of dynamic contrast-enhancement magnetic resonance imaging (DCE-MRI) has shown great promise in clinical practice, particularly for identifying the presence of breast disease. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-13 Lei Zhou , Yuzhong Zhang , Jiadong Zhang , Xuejun Qian , Chen Gong , Kun Sun , Zhongxiang Ding , Xing Wang , Zhenhui Li , Zaiyi Liu , Dinggang Shen

Dual-energy (DE) chest radiographs provide greater diagnostic information than standard radiographs by separating the image into bone and soft tissue, revealing suspicious lesions which may otherwise be obstructed from view. However,…

Computer Vision and Pattern Recognition · Computer Science 2021-04-15 Bo Zhou , Xunyu Lin , Brendan Eck , Jun Hou , David L. Wilson

Our objective is to show the feasibility of using simulated mammograms to detect mammographically-occult (MO) cancer in women with dense breasts and a normal screening mammogram who could be triaged for additional screening with magnetic…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Juhun Lee , Robert M. Nishikawa

Self-supervised models allow (pre-)training on unlabeled data and therefore have the potential to overcome the need for large annotated cohorts. One leading self-supervised model is the masked autoencoder (MAE) which was developed on…

Image and Video Processing · Electrical Eng. & Systems 2023-03-13 Daniel M. Lang , Eli Schwartz , Cosmin I. Bercea , Raja Giryes , Julia A. Schnabel

Magnetic resonance imaging (MRI) is a leading modality for the diagnosis of liver cancer, significantly improving the classification of the lesion and patient outcomes. However, traditional MRI faces challenges including risks from contrast…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Xiaojiao Xiao , Jianfeng Zhao , Qinmin Vivian Hu , Guanghui Wang

Breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) plays an important role in the screening and prognosis assessment of high-risk breast cancer. The segmentation of cancerous regions is essential useful for the subsequent…

Image and Video Processing · Electrical Eng. & Systems 2023-06-30 Yuming Zhong , Yi Wang

Full-Field Digital Mammography (FFDM) is the primary imaging modality for routine breast cancer screening; however, its effectiveness is limited in patients with dense breast tissue or fibrocystic conditions. Contrast-Enhanced Spectral…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Aurora Rofena , Claudia Lucia Piccolo , Bruno Beomonte Zobel , Paolo Soda , Valerio Guarrasi

This paper proposes an efficient solution for tumor segmentation and classification in breast ultrasound (BUS) images. We propose to add an atrous convolution layer to the conditional generative adversarial network (cGAN) segmentation model…

Image and Video Processing · Electrical Eng. & Systems 2019-07-02 Vivek Kumar Singh , Hatem A. Rashwan , Mohamed Abdel-Nasser , Md. Mostafa Kamal Sarker , Farhan Akram , Nidhi Pandey , Santiago Romani , Domenec Puig

We propose a new computer aided detection framework for tumours acquired on DCE-MRI (Dynamic Contrast Enhanced Magnetic Resonance Imaging) series on small animals. In this approach we consider DCE-MRI series as multivariate images. A full…

Image and Video Processing · Electrical Eng. & Systems 2019-10-29 Guillaume Noyel , Jesus Angulo , Dominique Jeulin , Daniel Balvay , Charles-André Cuenod

Dynamic Contrast-enhanced magnetic resonance imaging (DCE-MRI) is a tissue perfusion imaging technique. Some versatile free-breathing DCE-MRI techniques combining compressed sensing (CS) and parallel imaging with golden-angle radial…

Medical Physics · Physics 2020-07-08 Yuhan Hu , Xinlin Zhang , Li Feng , Dicheng Chen , Zhiping Yan , Xiaoyong Shen , Gen Yan , Lin Ou-yang , Xiaobo Qu

Recently, deep learning models have shown the potential to predict breast cancer risk and enable targeted screening strategies, but current models do not consider the change in the breast over time. In this paper, we present a new method,…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Hyeonsoo Lee , Junha Kim , Eunkyung Park , Minjeong Kim , Taesoo Kim , Thijs Kooi

Breast cancer is a significant cause of death from cancer in women globally, highlighting the need for improved diagnostic imaging to enhance patient outcomes. Accurate tumour identification is essential for diagnosis, treatment, and…

Image and Video Processing · Electrical Eng. & Systems 2024-05-15 Chi-en Amy Tai , Alexander Wong

Computer-aided breast cancer diagnosis in mammography is limited by inadequate data and the similarity between benign and cancerous masses. To address this, we propose a signed graph regularized deep neural network with adversarial…

Image and Video Processing · Electrical Eng. & Systems 2019-09-17 Heyi Li , Dongdong Chen , William H. Nailon , Mike E. Davies , David I. Laurenson

Computed tomography (CT) is critical for various clinical applications, e.g., radiotherapy treatment planning and also PET attenuation correction. However, CT exposes radiation during acquisition, which may cause side effects to patients.…

Computer Vision and Pattern Recognition · Computer Science 2016-12-19 Dong Nie , Roger Trullo , Caroline Petitjean , Su Ruan , Dinggang Shen

Supervised deep learning relies on the assumption that enough training data is available, which presents a problem for its application to several fields, like medical imaging. On the example of a binary image classification task (breast…

Computer Vision and Pattern Recognition · Computer Science 2019-02-22 Lukas Jendele , Ondrej Skopek , Anton S. Becker , Ender Konukoglu

Breast cancer is the second most common type of cancer in women in Canada and the United States, representing over 25\% of all new female cancer cases. As such, there has been immense research and progress on improving screening and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-07 Chi-en Amy Tai , Hayden Gunraj , Nedim Hodzic , Nic Flanagan , Ali Sabri , Alexander Wong

Purpose: To determine whether deep learning models can distinguish between breast cancer molecular subtypes based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and methods: In this institutional review…

Computer Vision and Pattern Recognition · Computer Science 2017-12-01 Zhe Zhu , Ehab Albadawy , Ashirbani Saha , Jun Zhang , Michael R. Harowicz , Maciej A. Mazurowski

In this paper, we describe how to apply image-to-image translation techniques to medical blood smear data to generate new data samples and meaningfully increase small datasets. Specifically, given the segmentation mask of the microscopy…

Computer Vision and Pattern Recognition · Computer Science 2019-03-11 Oleksandr Bailo , DongShik Ham , Young Min Shin