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In dynamic models of infectious disease transmission, typically various mixing patterns are imposed on the so-called Who-Acquires-Infection-From-Whom matrix (WAIFW). These imposed mixing patterns are based on prior knowledge of age-related…

In this paper we first introduce the general stochastic epidemic model for the spread of infectious diseases. Then we give methods for inferring model parameters such as the basic reproduction number $R_0$ and vaccination coverage $v_c$…

Methodology · Statistics 2014-11-14 Tom Britton , Federica Giardina

Epidemic outbreaks of new pathogens, or known pathogens in new populations, cause a great deal of fear because they are hard to predict. For theoretical models of disease spreading, on the other hand, quantities characterizing the outbreak…

Populations and Evolution · Quantitative Biology 2015-05-20 Petter Holme , Taro Takaguchi

This manuscript introduces a new analytical approach for studying the time evolution of disease spread on a finite size network. Our methodology can accommodate any disease with a general infectivity profile. This new approach is able to…

Statistical Mechanics · Physics 2010-05-25 B. Davoudi , B. Pourbohloul

Human to human transmissible infectious diseases spread in a population using human interactions as its transmission vector. The early stages of such an outbreak can be modeled by a graph whose edges encode these interactions between…

Populations and Evolution · Quantitative Biology 2020-06-11 Goncalo Oliveira

Let $(\xi_k,\eta_k)_{k\in\mathbb{N}}$ be independent identically distributed random vectors with arbitrarily dependent positive components. We call a (globally) perturbed random walk a random sequence $(T_k)_{k\in\mathbb{N}}$ defined by…

Probability · Mathematics 2020-12-08 Vladyslav Bohun , Alexander Iksanov , Alexander Marynych , Bohdan Rashytov

We investigate the time evolution of disease spread on a network by using the concept of generations. We derive a set of equations, which can be used to determine the average epidemic size. We find a very good agreement between the…

Statistical Mechanics · Physics 2010-05-24 B. Davoudi , F. Brauer , B. Pourbohloul

Infectious diseases, either emerging or long-lasting, place numerous people at risk and bring heavy public health burdens worldwide. In the process against infectious diseases, predicting the epidemic risk by modeling the disease…

Machine Learning · Computer Science 2023-08-08 Mutong Liu , Yang Liu , Jiming Liu

In many biological systems, the movement of individual agents is commonly characterized as having multiple qualitatively distinct behaviors that arise from various biophysical states. This is true for vesicles in intracellular transport,…

Subcellular Processes · Quantitative Biology 2022-07-25 Maria-Veronica Ciocanel , John Fricks , Peter R. Kramer , Scott A. McKinley

The time-to-recovery or time-to-death for various infectious diseases can vary significantly among individuals, influenced by several factors such as demographic differences, immune strength, medical history, age, pre-existing conditions,…

Applications · Statistics 2024-08-27 Samiran Ghosh , Malay Banerjee , Subhra Sankar Dhar , Siuli Mukhopadhyay

Epidemiological models describe the spread of an infectious disease within a population. They capture microscopic details on how the disease is passed on among individuals in various different ways, while making predictions about the state…

Populations and Evolution · Quantitative Biology 2024-02-27 Stefan Hohenegger , Francesco Sannino

Understanding how age-specific social contact patterns and susceptibility influence infectious disease transmission is crucial for accurate epidemic modeling. This study presents an eigenvector-based sensitivity analysis framework to…

Populations and Evolution · Quantitative Biology 2025-11-21 Evans Kiptoo Korir , Zsolt Vizi

In general, the rates of infection and removal (whether through recovery or death) are nonlinear functions of the number of infected and susceptible individuals. One of the simplest models for the spread of infectious diseases is the SIR…

Populations and Evolution · Quantitative Biology 2026-05-11 Seong Jun Park , M. Y. Choi

Mathematical and computational modeling approaches are increasingly used as quantitative tools in the analysis and forecasting of infectious disease epidemics. The growing need for realism in addressing complex public health questions is…

Dengue is a vector-borne disease transmitted by Aedes mosquitoes. The worldwide spread of these mosquitoes and the increasing disease burden have emphasized the need for a spatio-temporal risk map capable of assessing dengue outbreak…

Applications · Statistics 2023-10-11 Aram Vajdi , Lee W. Cohnstaedt , Caterina M. Scoglio

The annual occurrence of many infectious diseases remains a constant burden to public health systems. The seasonal patterns in respiratory disease incidence observed in temperate regions have been attributed to the impact of environmental…

Populations and Evolution · Quantitative Biology 2013-11-13 Marguerite Robinson , Yannis Drossinos , Nikolaos I. Stilianakis

We study the random times between successive cases in a transmission chain of infectious diseases with asymptomatic carriers. We derive the probability distribution of this generation time (in days) from a discrete-time epidemic model with…

Populations and Evolution · Quantitative Biology 2026-04-16 Jordi Ripoll , Joan Saldaña

Airborne infection risk analysis is usually performed for enclosed spaces where susceptible individuals are exposed to infectious airborne respiratory droplets by inhalation. It is usually based on exponential, dose-response models of which…

Populations and Evolution · Quantitative Biology 2024-08-01 Yannis Drossinos , Nikolaos I. Stilianakis

As global living standards improve and medical technology advances, many infectious diseases have been effectively controlled. However, certain diseases, such as the recent COVID-19 pandemic, continue to pose significant threats to public…

Numerical Analysis · Mathematics 2025-02-24 Ayesha Baig , Li Zhouxin

Reconstructing transmission networks is essential for identifying key factors like superspreaders and high-risk locations, which are critical for developing effective pandemic prevention strategies. In this study, we developed a Bayesian…

Quantitative Methods · Quantitative Biology 2024-09-10 Jianing Xu , Huimin Hu , Gregory Ellison , Lili Yu , Christopher Whalen , Liang Liu
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