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Knowledge graphs (KGs) are powerful tools for modelling complex, multi-relational data and supporting hypothesis generation, particularly in applications like drug repurposing. However, for predictive methods to gain acceptance as credible…

Artificial Intelligence · Computer Science 2026-02-06 Susana Nunes , Samy Badreddine , Catia Pesquita

Knowledge graph (KG) is used to represent data in terms of entities and structural relations between the entities. This representation can be used to solve complex problems such as recommendation systems and question answering. In this…

Artificial Intelligence · Computer Science 2022-12-09 Ajay Kumar Gogineni

As large language models (LLMs) continue to grow in size, their abilities to tackle complex tasks have significantly improved. However, issues such as hallucination and the lack of up-to-date knowledge largely remain unresolved. Knowledge…

Artificial Intelligence · Computer Science 2026-03-17 Lihui Liu

A prominent application of knowledge graph (KG) is document enrichment. Existing methods identify mentions of entities in a background KG and enrich documents with entity types and direct relations. We compute an entity relation subgraph…

Artificial Intelligence · Computer Science 2020-05-12 Shuxin Li , Zixian Huang , Gong Cheng , Evgeny Kharlamov , Kalpa Gunaratna

Large Language Models (LLMs) exhibit strong reasoning capabilities in complex tasks. However, they still struggle with hallucinations and factual errors in knowledge-intensive scenarios like knowledge graph question answering (KGQA). We…

Computation and Language · Computer Science 2025-11-12 Songze Li , Zhiqiang Liu , Zhengke Gui , Huajun Chen , Wen Zhang

To date, there are no effective treatments for most neurodegenerative diseases. Knowledge graphs can provide comprehensive and semantic representation for heterogeneous data, and have been successfully leveraged in many biomedical…

Artificial Intelligence · Computer Science 2022-11-30 Yi Nian , Xinyue Hu , Rui Zhang , Jingna Feng , Jingcheng Du , Fang Li , Yong Chen , Cui Tao

Knowledge Graph-based Retrieval-Augmented Generation (KG-RAG) significantly enhances the reasoning capabilities of LargeLanguage Models by leveraging structured knowledge. However, existing KG-RAG frameworks typically operate as open-loop…

Information Retrieval · Computer Science 2025-08-14 Xujie Yuan , Shimin Di , Jielong Tang , Libin Zheng , Jian Yin

Knowledge graphs (KGs) are powerful tools that codify relational behaviour between entities in knowledge bases. KGs can simultaneously model many different types of subject-predicate-object and higher-order relations. As such, they offer a…

Social and Information Networks · Computer Science 2020-10-27 Charilaos I. Kanatsoulis , Nicholas D. Sidiropoulos

Drug repurposing is more relevant than ever due to drug development's rising costs and the need to respond to emerging diseases quickly. Knowledge graph embedding enables drug repurposing using heterogeneous data sources combined with…

Drug repurposing plays a critical role in accelerating treatment discovery, especially for complex and rare diseases. Biomedical knowledge graphs (KGs), which encode rich clinical associations, have been widely adopted to support this task.…

Computation and Language · Computer Science 2025-10-15 Chengrui Xiang , Tengfei Ma , Xiangzheng Fu , Yiping Liu , Bosheng Song , Xiangxiang Zeng

Knowledge graphs (KGs) offer a rich representation for relational knowledge, but their irregular structure makes retrieval challenging: ego-graph expansion grows rapidly, and dense embedding methods struggle with multi-hop compositional…

Machine Learning · Computer Science 2026-05-25 Hamed Shirzad , Frederik Wenkel , Dominique Beaini , Danica J. Sutherland , Emmanuel Noutahi

Understanding how small molecules perturb gene expression is essential for uncovering drug mechanisms, predicting off-target effects, and identifying repurposing opportunities. While prior deep learning frameworks have integrated multimodal…

Machine Learning · Computer Science 2026-01-01 Pascal Passigan , Kevin Zhu , Angelina Ning

Medical knowledge bases (KBs), distilled from biomedical literature and regulatory actions, are expected to provide high-quality information to facilitate clinical decision making. Entity disambiguation (also referred to as entity linking)…

Information Retrieval · Computer Science 2021-04-06 Alina Vretinaris , Chuan Lei , Vasilis Efthymiou , Xiao Qin , Fatma Özcan

Adoption of recently developed methods from machine learning has given rise to creation of drug-discovery knowledge graphs (KG) that utilize the interconnected nature of the domain. Graph-based modelling of the data, combined with KG…

Machine Learning · Computer Science 2022-07-27 Stephen Bonner , Ufuk Kirik , Ola Engkvist , Jian Tang , Ian P Barrett

Large Language Models (LLMs) and Knowledge Graphs (KGs) offer a promising approach to robust and explainable Question Answering (QA). While LLMs excel at natural language understanding, they suffer from knowledge gaps and hallucinations.…

Machine Learning · Computer Science 2025-04-15 Jasper Linders , Jakub M. Tomczak

Retrieval-augmented generation (RAG) systems have been widely adopted in contemporary large language models (LLMs) due to their ability to improve generation quality while reducing the required input context length. In this work, we focus…

Computation and Language · Computer Science 2026-04-07 Tianyi Zhang , Andreas Marfurt

Retrieval-Augmented Generation (RAG) enhances language models by grounding responses in external information, yet explainability remains a critical challenge, particularly when retrieval relies on unstructured text. Knowledge graphs (KGs)…

Machine Learning · Computer Science 2025-07-14 Georgios Balanos , Evangelos Chasanis , Konstantinos Skianis , Evaggelia Pitoura

Large Language Models (LLMs) have demonstrated strong capabilities in web search and reasoning. However, their dependence on static training corpora makes them prone to factual errors and knowledge gaps. Retrieval-Augmented Generation (RAG)…

Artificial Intelligence · Computer Science 2026-01-26 Jiasheng Xu , Mingda Li , Yongqiang Tang , Peijie Wang , Wensheng Zhang

Knowledge graph (KG) embedding has been used to benefit the diagnosis of animal diseases by analyzing electronic medical records (EMRs), such as notes and veterinary records. However, learning representations to capture entities and…

Artificial Intelligence · Computer Science 2023-09-08 Van Thuy Hoang , Sang Thanh Nguyen , Sangmyeong Lee , Jooho Lee , Luong Vuong Nguyen , O-Joun Lee

Knowledge graphs (KGs) play a crucial role in many applications, such as question answering, but incompleteness is an urgent issue for their broad application. Much research in knowledge graph completion (KGC) has been performed to resolve…

Artificial Intelligence · Computer Science 2023-01-10 Yinyu Lan , Shizhu He , Kang Liu , Jun Zhao
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