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The coronavirus pandemic has rapidly evolved into an unprecedented crisis. The susceptible-infectious-removed (SIR) model and its variants have been used for modeling the pandemic. However, time-independent parameters in the classical…

Populations and Evolution · Quantitative Biology 2020-09-09 Hyokyoung G. Hong , Yi Li

In this paper, we conduct mathematical and numerical analyses to address the following crucial questions for COVID-19: (Q1) Is it possible to contain COVID-19? (Q2) When will be the peak and the end of the epidemic? (Q3) How do the…

Populations and Evolution · Quantitative Biology 2020-09-22 Yi-Cheng Chen , Ping-En Lu , Cheng-Shang Chang , Tzu-Hsuan Liu

The COVID-19 pandemic has had worldwide devastating effects on human lives, highlighting the need for tools to predict its development. Dynamics of such public-health threats can often be efficiently analysed through simple models that help…

Populations and Evolution · Quantitative Biology 2021-06-04 Pedro L. de Andres , Lucia de Andres-Bragado , Linard D. Hoessly

Transmission rates in epidemic outbreaks may vary over time depending on the societal response. Non-pharmacological mitigation strategies such as social distancing and the adoption of protective equipment aim precisely at reducing…

Populations and Evolution · Quantitative Biology 2020-12-24 Elisa Franco

This paper extends the canonical model of epidemiology, the SIRD model, to allow for time-varying parameters for real-time measurement and prediction of the trajectory of the Covid-19 pandemic. Time variation in model parameters is captured…

Econometrics · Economics 2023-02-01 Cem Cakmakli , Yasin Simsek

This paper seeks to study the evolution of the COVID-19 pandemic based on daily published data from Worldometer website, using a time-dependent SIR model. Our findings indicate that this model fits well such data, for different chosen…

Populations and Evolution · Quantitative Biology 2023-11-28 Rawan H. Madi , Sophie M. Moufawad , Nabil R. Nassif

In this article, we present a modification to the network-based stochastic SEIR epidemic model which allows for modifications to the underlying contact network to account for the effects of quarantine. We also discuss the changes needed to…

Populations and Evolution · Quantitative Biology 2020-08-05 Chris Groendyke , Adam Combs

The role of epidemiological models is crucial for informing public health officials during a public health emergency, such as the COVID-19 pandemic. However, traditional epidemiological models fail to capture the time-varying effects of…

Methodology · Statistics 2022-06-17 Adam Spannaus , Theodore Papamarkou , Samantha Erwin , J. Blair Christian

A standard model for epidemics is the SIR model on a graph. We introduce a simple algorithm that uses the early infection times from a sample path of the SIR model to estimate the parameters this model, and we provide a performance…

Information Theory · Computer Science 2020-08-11 Charles Clum , Dustin G. Mixon

Susceptible-Exposed-Infectious-Recovered (SEIR) models with inter-individual variation in susceptibility or exposure to infection were proposed early in the COVID-19 pandemic as a potential element of the mathematical/statistical toolset…

Applications · Statistics 2025-10-28 Ibrahim Mohammed , Chris Robertson , M. Gabriela M. Gomes

We consider a stochastic Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model with a contact rate that fluctuates seasonally. Through the use of a nonlinear, stochastic projection, we are able to analytically determine the…

Populations and Evolution · Quantitative Biology 2013-09-11 Eric Forgoston , Ira B. Schwartz

This paper focuses on and analyzes realistic SIR models that take stochasticity into account. The proposed systems are applicable to most incidence rates that are used in the literature including the bilinear incidence rate, the…

Probability · Mathematics 2024-07-10 Nguyen Du , Alexandru Hening , Nhu Nguyen , George Yin

We tackle limitations of ordinary differential equation-driven Susceptible-Infections-Removed (SIR) models and their extensions that have recently be employed for epidemic nowcasting and forecasting. In particular, we deal with challenges…

Computation · Statistics 2026-02-10 Angelos Alexopoulos , Paul Birrell , Daniela De Angelis

The dramatic outbreak of the coronavirus disease 2019 (COVID-19) pandemics and its ongoing progression boosted the scientific community's interest in epidemic modeling and forecasting. The SIR (Susceptible-Infected-Removed) model is a…

Populations and Evolution · Quantitative Biology 2021-02-24 Dimiter Prodanov

The vast majority of models for the spread of communicable diseases are parametric in nature and involve underlying assumptions about how the disease spreads through a population. In this article we consider the use of Bayesian…

Methodology · Statistics 2017-06-12 Theodore Kypraios , Philip D. O'Neill

Understanding infectious disease spread remains a critical public health challenge, particularly given the interplay between household dynamics and community transmission patterns. Traditional epidemiological models often oversimplify these…

Populations and Evolution · Quantitative Biology 2026-01-21 Houda Yaqine , Christiane Fuchs

In this paper, we study the effectiveness of the modelling approach on the pandemic due to the spreading of the novel COVID-19 disease and develop a susceptible-infected-removed (SIR) model that provides a theoretical framework to…

Populations and Evolution · Quantitative Biology 2020-08-26 Ian Cooper , Argha Mondal , Chris G. Antonopoulos

Motivated by the ongoing pandemic COVID-19, we propose a closed-loop framework that combines inference from testing data, learning the parameters of the dynamics and optimal resource allocation for controlling the spread of the…

Physics and Society · Physics 2021-04-27 Ashish R. Hota , Jaydeep Godbole , Philip E Paré

We propose a framework for Bayesian non-parametric estimation of the rate at which new infections occur assuming that the epidemic is partially observed. The developed methodology relies on modelling the rate at which new infections occur…

Methodology · Statistics 2014-12-16 Edward S. Knock , Theodore Kypraios

Fractional-order SIR models have become increasingly popular in the literature in recent years, however unlike the standard SIR model, they often lack a derivation from an underlying stochastic process. Here we derive a fractional-order…

Populations and Evolution · Quantitative Biology 2016-03-31 Christopher N Angstmann , Bruce I Henry , Anna V McGann