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Whole-slide image analysis is essential for diagnostic tasks in pathology, yet existing deep learning methods primarily rely on flat classification, ignoring hierarchical relationships among class labels. In this study, we propose HiClass,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Keunho Byeon , Jinsol Song , Seong Min Hong , Yosep Chong , Jin Tae Kwak

Early identification of stroke symptoms is essential for enabling timely intervention and improving patient outcomes, particularly in prehospital settings. This study presents a fast, non-invasive multimodal deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Ngoc-Khai Hoang , Thi-Nhu-Mai Nguyen , Huy-Hieu Pham

Chronic wounds, including diabetic foot ulcers which affect up to one-third of people with diabetes, impose a substantial clinical and economic burden, with U.S. healthcare costs exceeding 25 billion dollars annually. Current wound…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Moses Kiprono

Early detection of oral cancer and potentially malignant diseases is a major challenge in low-resource settings due to the scarcity of annotated data. We provide a unified approach for four-class oral lesion classification that incorporates…

Image and Video Processing · Electrical Eng. & Systems 2026-02-05 Rupam Mukherjee , Rajkumar Daniel , Soujanya Hazra , Shirin Dasgupta , Subhamoy Mandal

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

Bone marrow cytology is required to make a hematological diagnosis, influencing critical clinical decision points in hematology. However, bone marrow cytology is tedious, limited to experienced reference centers and associated with high…

Image and Video Processing · Electrical Eng. & Systems 2021-07-09 Rohollah Moosavi Tayebi , Youqing Mu , Taher Dehkharghanian , Catherine Ross , Monalisa Sur , Ronan Foley , Hamid R. Tizhoosh , Clinton JV Campbell

Multi-organ segmentation holds paramount significance in many clinical tasks. In practice, compared to large fully annotated datasets, multiple small datasets are often more accessible and organs are not labelled consistently. Normally, an…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Zhendi Gong , Susan Francis , Eleanor Cox , Stamatios N. Sotiropoulos , Dorothee P. Auer , Guoping Qiu , Andrew P. French , Xin Chen

Lesion detection is an important problem within medical imaging analysis. Most previous work focuses on detecting and segmenting a specialized category of lesions (e.g., lung nodules). However, in clinical practice, radiologists are…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Ke Yan , Jinzheng Cai , Adam P. Harrison , Dakai Jin , Jing Xiao , Le Lu

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

Machine Learning · Computer Science 2025-11-07 Anzhuo Xie , Wei-Chen Chang

Medical multimodal representation learning aims to integrate heterogeneous data into unified patient representations to support clinical outcome prediction. However, real-world medical datasets commonly contain systematic biases from…

Machine Learning · Computer Science 2026-05-19 Xiaoguang Zhu , Linxiao Gong , Lianlong Sun , Yang Liu , Haoyu Wang , Jing Liu

Accurate detection and classification of nuclei in histopathology images are critical for diagnostic and research applications. We present KongNet, a multi-headed deep learning architecture featuring a shared encoder and parallel,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-13 Jiaqi Lv , Esha Sadia Nasir , Kesi Xu , Mostafa Jahanifar , Brinder Singh Chohan , Behnaz Elhaminia , Shan E Ahmed Raza

Purposes: This study aimed to develop a computed tomography (CT)-based multi-organ segmentation model for delineating organs-at-risk (OARs) in pediatric upper abdominal tumors and evaluate its robustness across multiple datasets. Materials…

Machine learning holds promise for advancing clinical decision support, yet it remains unclear when multimodal learning truly helps in practice, particularly under modality missingness and fairness constraints. In this work, we conduct a…

Machine Learning · Computer Science 2026-03-02 Kejing Yin , Haizhou Xu , Wenfang Yao , Chen Liu , Zijie Chen , Yui Haang Cheung , William K. Cheung , Jing Qin

Identification of burn depth with sufficient accuracy is a challenging problem. This paper presents a deep convolutional neural network to classify burn depth based on altered tissue morphology of burned skin manifested as texture patterns…

Image and Video Processing · Electrical Eng. & Systems 2022-03-31 Sangrock Lee , Rahul , James Lukan , Tatiana Boyko , Kateryna Zelenova , Basiel Makled , Conner Parsey , Jack Norfleet , Suvranu De

Many skin lesion analysis (SLA) methods recently focused on developing a multi-modal-based multi-label classification method due to two factors. The first is multi-modal data, i.e., clinical and dermoscopy images, which can provide…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Peng Tang , Yang Nan , Tobias Lasser

This contribution presents a deep-learning method for extracting and fusing image information acquired from different viewpoints, with the aim to produce more discriminant object features for the identification of the type of kidney stones…

Molecular subtyping of breast cancer is crucial for personalized treatment and prognosis. Traditional classification approaches rely on either histopathological images or gene expression profiling, limiting their predictive power. In this…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Amin Honarmandi Shandiz

The analysis of fundus images is critical for the early detection and diagnosis of retinal diseases such as Diabetic Retinopathy (DR), Glaucoma, and Age-related Macular Degeneration (AMD). Traditional diagnostic workflows, however, often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Faisal Ahmed

Background. Subdural hematoma (SDH) is a common neurosurgical emergency, with increasing incidence in aging populations. Rapid and accurate identification is essential to guide timely intervention, yet existing automated tools focus…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Vasiliki Stoumpou , Rohan Kumar , Bernard Burman , Diego Ojeda , Tapan Mehta , Dimitris Bertsimas

Multimodal clinical data are characterized by high dimensionality, heterogeneous representations, and structured missingness, posing significant challenges for predictive modeling, data integration, and interpretability. We propose BIONIC…