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We present an algorithm to identify individual neural spikes observed on high-density multi-electrode arrays (MEAs). Our method can distinguish large numbers of distinct neural units, even when spikes overlap, and accounts for intrinsic…

Neurons and Cognition · Quantitative Biology 2013-08-01 Jason S. Prentice , Jan Homann , Kristina D. Simmons , Gašper Tkačik , Vijay Balasubramanian , Philip C. Nelson

One of the main current issues in Neurobiology concerns the understanding of interrelated spiking activity among multineuronal ensembles and differences between stimulus-driven and spontaneous activity in neurophysiological experiments.…

Neurons and Cognition · Quantitative Biology 2017-10-13 Ludmila Brochini , Antonio Galves , Pierre Hodara , Guilherme Ost , Christophe Pouzat

Spiking Neural Networks (SNNs) compute and communicate with asynchronous binary temporal events that can lead to significant energy savings with neuromorphic hardware. Recent algorithmic efforts on training SNNs have shown competitive…

Computer Vision and Pattern Recognition · Computer Science 2021-10-18 Youngeun Kim , Priyadarshini Panda

Recent advances in neural recording technology allow simultaneously recording action potentials from hundreds to thousands of neurons in awake, behaving animals. However, characterizing spike patterns in the resulting data, and linking…

Spike synchrony, which occurs in various cortical areas in response to specific perception, action and memory tasks, has sparked a long-standing debate on the nature of temporal organization in cortex. One prominent view is that this type…

Neurons and Cognition · Quantitative Biology 2017-12-18 Clemens Korndörfer , Ekkehard Ullner , Jordi García-Ojalvo , Gordon Pipa

In electrophysiology, microelectrodes are the primary source for recording neural data of single neurons (single unit activity). These microelectrodes can be implanted individually, or in the form of microelectrodes arrays, consisting of…

The advent of large-scale and high-density extracellular recording devices allows simultaneous recording from thousands of neurons. However, the complexity and size of the data makes it mandatory to develop robust algorithms for fully…

Neurons and Cognition · Quantitative Biology 2019-12-03 Gerrit Hilgen

Diagnostic reasoning is a key component of many professions. To improve students' diagnostic reasoning skills, educational psychologists analyse and give feedback on epistemic activities used by these students while diagnosing, in…

How neural networks in the human brain represent commonsense knowledge, and complete related reasoning tasks is an important research topic in neuroscience, cognitive science, psychology, and artificial intelligence. Although the…

Neural and Evolutionary Computing · Computer Science 2022-07-13 Hongjian Fang , Yi Zeng , Jianbo Tang , Yuwei Wang , Yao Liang , Xin Liu

Neuro-inspired models and systems have great potential for applications in unconventional computing. Often, the mechanisms of biological neurons are modeled or mimicked in simulated or physical systems in an attempt to harness some of the…

Neural and Evolutionary Computing · Computer Science 2021-10-18 Jørgen Jensen Farner , Håkon Weydahl , Ruben Jahren , Ola Huse Ramstad , Stefano Nichele , Kristine Heiney

Spiking neural networks (SNNs) are distributed trainable systems whose computing elements, or neurons, are characterized by internal analog dynamics and by digital and sparse synaptic communications. The sparsity of the synaptic spiking…

Machine Learning · Computer Science 2020-01-08 Hyeryung Jang , Osvaldo Simeone , Brian Gardner , André Grüning

To gain a deeper understanding of the behavior and learning dynamics of (deep) artificial neural networks, it is valuable to employ mathematical abstractions and models. These tools provide a simplified perspective on network performance…

Machine Learning · Computer Science 2023-08-03 Stephan Johann Lehmler , Muhammad Saif-ur-Rehman , Tobias Glasmachers , Ioannis Iossifidis

The rapid emergence of highly adaptable and reusable artificial intelligence (AI) models is set to revolutionize the medical field, particularly in the diagnosis and management of Parkinson's disease (PD). Currently, there are no effective…

Machine Learning · Computer Science 2025-02-18 Aite Zhao , Yongcan Liu , Xinglin Yu , Xinyue Xing

Experimental studies support the notion of spike-based neuronal information processing in the brain, with neural circuits exhibiting a wide range of temporally-based coding strategies to rapidly and efficiently represent sensory stimuli.…

Neural and Evolutionary Computing · Computer Science 2020-08-18 Brian Gardner , André Grüning

A main concern in cognitive neuroscience is to decode the overt neural spike train observations and infer latent representations under neural circuits. However, traditional methods entail strong prior on network structure and hardly meet…

Neurons and Cognition · Quantitative Biology 2019-11-22 Zhijie Chen , Junchi Yan , Longyuan Li , Xiaokang Yang

Spiking neural networks (SNNs), central to computational neuroscience and neuromorphic machine learning (ML), require efficient simulation and gradient-based training. While AI accelerators offer promising speedups, gradient-based SNNs…

Neural and Evolutionary Computing · Computer Science 2025-12-08 Lennart P. L. Landsmeer , Amirreza Movahedin , Said Hamdioui , Christos Strydis

Techniques for recording large-scale neuronal spiking activity are developing very fast. This leads to an increasing demand for algorithms capable of analyzing large amounts of experimental spike train data. One of the most crucial and…

Data Analysis, Statistics and Probability · Physics 2015-04-16 Thomas Kreuz , Mario Mulansky , Nebojsa Bozanic

Biological neurons communicate with a sparing exchange of pulses - spikes. It is an open question how real spiking neurons produce the kind of powerful neural computation that is possible with deep artificial neural networks, using only so…

Neural and Evolutionary Computing · Computer Science 2016-09-08 Davide Zambrano , Sander M. Bohte

We address the problem of finding patterns from multi-neuronal spike trains that give us insights into the multi-neuronal codes used in the brain and help us design better brain computer interfaces. We focus on the synchronous firings of…

Neural and Evolutionary Computing · Computer Science 2010-06-09 Raajay Viswanathan , P. S. Sastry , K. P. Unnikrishnan

In drug-resistant epilepsy, presurgical evaluation of epilepsy can be considered. Magnetoencephalography (MEG) has been shown to be an effective exam to inform the localization of the epileptogenic zone through the localization of…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Pauline Mouches , Julien Jung , Armand Demasson , Agnès Guinard , Romain Bouet , Rosalie Marchal , Romain Quentin
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