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The Segment Anything Model (SAM) marks a significant advancement in segmentation models, offering robust zero-shot abilities and dynamic prompting. However, existing medical SAMs are not suitable for the multi-scale nature of whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hong Liu , Haosen Yang , Paul J. van Diest , Josien P. W. Pluim , Mitko Veta

Segment Anything Model (SAM) has recently achieved amazing results in the field of natural image segmentation. However, it is not effective for medical image segmentation, owing to the large domain gap between natural and medical images. In…

Image and Video Processing · Electrical Eng. & Systems 2024-04-24 Zhengzheng Tu , Le Gu , Xixi Wang , Bo Jiang

Melanoma segmentation in Whole Slide Images (WSIs) is useful for prognosis and the measurement of crucial prognostic factors such as Breslow depth and primary invasive tumor size. In this paper, we present a novel approach that uses the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Qingyuan Liu , Avideh Zakhor

Recent "segment anything" efforts show promise by learning from large-scale data, but adapting such models directly to medical images remains challenging due to the complexity of medical data, noisy annotations, and continual learning…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Zhiling Yan , Sifan Song , Dingjie Song , Yiwei Li , Rong Zhou , Weixiang Sun , Zhennong Chen , Sekeun Kim , Hui Ren , Tianming Liu , Quanzheng Li , Xiang Li , Lifang He , Lichao Sun

Segment Anything Model (SAM) has gained significant recognition in the field of semantic segmentation due to its versatile capabilities and impressive performance. Despite its success, SAM faces two primary limitations: (1) it relies…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Yuchen Li , Li Zhang , Youwei Liang , Pengtao Xie

Recent studies suggest that Visual Language Models (VLMs) hold great potential for tasks such as automated medical diagnosis. However, processing complex three-dimensional (3D) multimodal medical images poses significant challenges -…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Hao Wu , Hui Li , Yiyun Su

Segment Anything Model (SAM) has gained significant attention because of its ability to segment various objects in images given a prompt. The recently developed SAM 2 has extended this ability to video inputs. This opens an opportunity to…

Computer Vision and Pattern Recognition · Computer Science 2024-08-23 Haoyu Dong , Hanxue Gu , Yaqian Chen , Jichen Yang , Yuwen Chen , Maciej A. Mazurowski

Recently, large vision model, Segment Anything Model (SAM), has revolutionized the computer vision field, especially for image segmentation. SAM presented a new promptable segmentation paradigm that exhibit its remarkable zero-shot…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Chenglong Wang , Dexuan Li , Sucheng Wang , Chengxiu Zhang , Yida Wang , Yun Liu , Guang Yang

Recently, the Segment Anything Model (SAM) has demonstrated promising segmentation capabilities in a variety of downstream segmentation tasks. However in the context of universal medical image segmentation there exists a notable performance…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Chao Qin , Jiale Cao , Huazhu Fu , Fahad Shahbaz Khan , Rao Muhammad Anwer

Current AI-assisted skin image diagnosis has achieved dermatologist-level performance in classifying skin cancer, driven by rapid advancements in deep learning architectures. However, unlike traditional vision tasks, skin images in general…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Xin Hu , Janet Wang , Jihun Hamm , Rie R Yotsu , Zhengming Ding

Recently, Meta AI Research approaches a general, promptable Segment Anything Model (SAM) pre-trained on an unprecedentedly large segmentation dataset (SA-1B). Without a doubt, the emergence of SAM will yield significant benefits for a wide…

Computer Vision and Pattern Recognition · Computer Science 2024-08-23 Wei Ji , Jingjing Li , Qi Bi , Tingwei Liu , Wenbo Li , Li Cheng

Following the successful paradigm shift of large language models, leveraging pre-training on a massive corpus of data and fine-tuning on different downstream tasks, generalist models have made their foray into computer vision. The…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Andrea Moglia , Matteo Leccardi , Matteo Cavicchioli , Alice Maccarini , Marco Marcon , Luca Mainardi , Pietro Cerveri

Recent advances in segmentation foundation models have enabled accurate and efficient segmentation across a wide range of natural images and videos, but their utility to medical data remains unclear. In this work, we first present a…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Jun Ma , Sumin Kim , Feifei Li , Mohammed Baharoon , Reza Asakereh , Hongwei Lyu , Bo Wang

Deep learning based methods often suffer from performance degradation caused by domain shift. In recent years, many sophisticated network structures have been designed to tackle this problem. However, the advent of large model trained on…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Zhikai Wei , Wenhui Dong , Peilin Zhou , Yuliang Gu , Zhou Zhao , Yongchao Xu

Vision foundation models like the Segment Anything Model (SAM), pretrained on large-scale natural image datasets, often struggle in medical image segmentation due to a lack of domain-specific adaptation. In clinical practice, fine-tuning…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Zelin Liu , Sicheng Dong , Bocheng Li , Yixuan Yang , Jiacheng Ruan , Chenxu Zhou , Suncheng Xiang

Medical imaging plays a critical role in the diagnosis and treatment planning of various medical conditions, with radiology and pathology heavily reliant on precise image segmentation. The Segment Anything Model (SAM) has emerged as a…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Amin Ranem , Niklas Babendererde , Moritz Fuchs , Anirban Mukhopadhyay

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

With the emergence of the Segment Anything Model (SAM) as a foundational model for image segmentation, its application has been extensively studied across various domains, including the medical field. However, its potential in the context…

Computer Vision and Pattern Recognition · Computer Science 2023-10-17 SeungKyu Kim , Hyun-Jic Oh , Seonghui Min , Won-Ki Jeong

The introduction of saliency map algorithms as an approach for assessing the interoperability of images has allowed for a deeper understanding of current black-box models with Artificial Intelligence. Their rise in popularity has led to…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Evan Kellener , Ihina Nath , An Ngo , Thomas Nguyen , Joshua Schuman , Coen Adler , Arnav Kartikeya

Universal medical image segmentation models have emerged as a promising paradigm due to their strong generalizability across diverse tasks, showing great potential for a wide range of clinical applications. This potential has been partly…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Yanwu Yang , Guinan Su , Jiesi Hu , Francesco Sammarco , Jonas Geiping , Thomas Wolfers