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This article presents a convolutional neural network for the automatic segmentation of brain tumors in multimodal 3D MR images based on a U-net architecture.We evaluate the use of a densely connected convolutional network encoder (DenseNet)…

Accurate evaluation of the response of glioblastoma to therapy is crucial for clinical decision-making and patient management. The Response Assessment in Neuro-Oncology (RANO) criteria provide a standardized framework to assess patients'…

With the rise in importance of personalized medicine, we trained personalized neural networks to detect tumor progression in longitudinal datasets. The model was evaluated on two datasets with a total of 64 scans from 32 patients diagnosed…

Glioblastoma is among the most aggressive brain tumors in adults, characterized by patient-specific invasion patterns driven by the underlying brain microstructure. In this work, we present a proof-of-concept for a mathematical model of GBL…

A brain tumour is a mass or cluster of abnormal cells in the brain, which has the possibility of becoming life-threatening because of its ability to invade neighbouring tissues and also form metastases. An accurate diagnosis is essential…

Glioblastoma, the most aggressive primary brain tumor, poses a severe clinical challenge due to its diffuse microscopic infiltration, which remains largely undetected on standard MRI. As a result, current radiotherapy planning employs a…

Motivated by the need for advanced solutions in the segmentation and inpainting of glioma-affected brain regions in multi-modal magnetic resonance imaging (MRI), this study presents an integrated approach leveraging the strengths of…

Cancer is a complex disease, the understanding and treatment of which are being aided through increases in the volume of collected data and in the scale of deployed computing power. Consequently, there is a growing need for the development…

Surgery for gliomas (intrinsic brain tumors), especially when low-grade, is challenging due to the infiltrative nature of the lesion. Currently, no real-time, intra-operative, label-free and wide-field tool is available to assist and guide…

We propose a fine-tuning algorithm for brain tumor segmentation that needs only a few data samples and helps networks not to forget the original tasks. Our approach is based on active learning and meta-learning. One of the difficulties in…

Survival prediction models can potentially be used to guide treatment of glioblastoma patients. However, currently available MR imaging biomarkers holding prognostic information are often challenging to interpret, have difficulties…

Accurate medical imaging segmentation is critical for precise and effective medical interventions. However, despite the success of convolutional neural networks (CNNs) in medical image segmentation, they still face challenges in handling…

Classifying the various shapes and attributes of a glioma cell nucleus is crucial for diagnosis and understanding the disease. We investigate automated classification of glioma nuclear shapes and visual attributes using Convolutional Neural…

Brain plays a crucial role in regulating body functions and cognitive processes, with brain tumors posing significant risks to human health. Precise and prompt detection is a key factor in proper treatment and better patient outcomes.…

Magnetic Resonance Imaging (MRI) is widely recognized as the most reliable tool for detecting tumors due to its capability to produce detailed images that reveal their presence. However, the accuracy of diagnosis can be compromised when…

Gliomas are the most common malignant brain tumourswith intrinsic heterogeneity. Accurate segmentation of gliomas and theirsub-regions on multi-parametric magnetic resonance images (mpMRI)is of great clinical importance, which defines…

Deep learning has significantly advanced automated brain tumor diagnosis, yet clinical adoption remains limited by interpretability and computational constraints. Conventional models often act as opaque ''black boxes'' and fail to quantify…

Inspired by the success of Convolutional Neural Networks (CNN), we develop a novel Computer Aided Detection (CADe) system using CNN for Glioblastoma Multiforme (GBM) detection and segmentation from multi channel MRI data. A two-stage…

Brain tumors pose a serious health threat due to their rapid growth and potential for metastasis. While medical imaging has advanced significantly, accurately identifying and characterizing these tumors remains a challenge. This study…

Accurate brain tumor segmentation in the early stages of the disease is crucial for the treatment's effectiveness, avoiding exhaustive visual inspection of a qualified specialist on 3D MR brain images of multiple protocols (e.g., T1, T2,…