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Digital pathology is not only one of the most promising fields of diagnostic medicine, but at the same time a hot topic for fundamental research. Digital pathology is not just the transfer of histopathological slides into digital…

Artificial Intelligence · Computer Science 2017-12-20 Andreas Holzinger , Bernd Malle , Peter Kieseberg , Peter M. Roth , Heimo Müller , Robert Reihs , Kurt Zatloukal

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

Domain generalization (DG) strives to address distribution shifts across diverse environments to enhance model's generalizability. Current DG approaches are confined to acquiring robust representations with continuous features, specifically…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Shaocong Long , Qianyu Zhou , Xikun Jiang , Chenhao Ying , Lizhuang Ma , Yuan Luo

Cancer is a complex disease, the understanding and treatment of which are being aided through increases in the volume of collected data and in the scale of deployed computing power. Consequently, there is a growing need for the development…

Computer assisted diagnosis in digital pathology is becoming ubiquitous as it can provide more efficient and objective healthcare diagnostics. Recent advances have shown that the convolutional Neural Network (CNN) architectures, a…

Image and Video Processing · Electrical Eng. & Systems 2022-01-05 Sruthi Krishna , Suganthi S. S , Shivsubramani Krishnamoorthy , Arnav Bhavsar

Foundation models have emerged as a powerful paradigm in computational pathology (CPath), enabling scalable and generalizable analysis of histopathological images. While early developments centered on uni-modal models trained solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Xiaohui Chen , Yi He , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Breast Ultrasound plays a vital role in cancer diagnosis as a non-invasive approach with cost-effective. In recent years, with the development of deep learning, many CNN-based approaches have been widely researched in both tumor…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Dat T. Chung , Minh-Anh Dang , Mai-Anh Vu , Minh T. Nguyen , Thanh-Huy Nguyen , Vinh Q. Dinh

The vast amount of health data has been continuously collected for each patient, providing opportunities to support diverse healthcare predictive tasks such as seizure detection and hospitalization prediction. Existing models are mostly…

Machine Learning · Computer Science 2023-02-16 Chaoqi Yang , M. Brandon Westover , Jimeng Sun

Geometric deep learning is an emerging technique in Artificial Intelligence (AI) driven cheminformatics, however the unique implications of different Graph Neural Network (GNN) architectures are poorly explored, for this space. This study…

Data limitation is a significant challenge in applying deep learning to medical images. Recently, the diffusion probabilistic model (DPM) has shown the potential to generate high-quality images by converting Gaussian random noise into…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Sepehr Salem Ghahfarokhi , Tyrell To , Julie Jorns , Tina Yen , Bing Yu , Dong Hye Ye

Failures in Phase 3 clinical trials contribute to expensive cost of drug development in oncology. To drastically reduce such cost, responders to an oncology treatment need to be identified early on in the drug development process with…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Qi Tang , Vardaan Kishore Kumar

Clinical cystoscopy, the current standard for bladder cancer diagnosis, suffers from significant reliance on physician expertise, leading to variability and subjectivity in diagnostic outcomes. There is an urgent need for objective,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jinliang Yu , Mingduo Xie , Yue Wang , Tianfan Fu , Xianglai Xu , Jiajun Wang

Differentiating true tumor progression (TP) from treatment-related pseudoprogression (PsP) in glioblastoma remains challenging, especially at early follow-up. We present the first stage-specific, cross-sectional benchmarking of deep…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Wenhao Guo , Golrokh Mirzaei

Pathology images are crucial for diagnosing and managing various diseases by visualizing cellular and tissue-level abnormalities. Recent advancements in artificial intelligence (AI), particularly multimodal models like ChatGPT, have shown…

Human-Computer Interaction · Computer Science 2024-09-25 Mianxin Liu , Jianfeng Wu , Fang Yan , Hongjun Li , Wei Wang , Shaoting Zhang , Zhe Wang

Multi-Source Domain Generalization (DG) is the task of training on multiple source domains and achieving high classification performance on unseen target domains. Recent methods combine robust features from web-scale pretrained backbones…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Piotr Teterwak , Kuniaki Saito , Theodoros Tsiligkaridis , Bryan A. Plummer , Kate Saenko

Accurate brain tumor classification is critical for intra-operative decision making in neuro-oncological surgery. However, existing approaches are restricted to a fixed set of predefined classes and are therefore unable to capture patterns…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Matthias Perkonigg , Patrick Rockenschaub , Georg Göbel , Adelheid Wöhrer

Despite the advances in medicine, cancer has remained a formidable challenge. Particularly in the case of pancreatic tumors, characterized by their diversity and late diagnosis, early detection poses a significant challenge crucial for…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Reza Babaei , Samuel Cheng , Theresa Thai , Shangqing Zhao

Supervised deep learning algorithms have enabled significant performance gains in medical image classification tasks. But these methods rely on large labeled datasets that require resource-intensive expert annotation. Semi-supervised…

Medical imaging datasets usually exhibit domain shift due to the variations of scanner vendors, imaging protocols, etc. This raises the concern about the generalization capacity of machine learning models. Domain generalization (DG), which…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Chenxin Li , Qi Qi , Xinghao Ding , Yue Huang , Dong Liang , Yizhou Yu

Deep learning (DL)-based image reconstruction methods for photoacoustic computed tomography (PACT) have developed rapidly in recent years. However, most existing methods have not employed standardized datasets, and their evaluations rely on…

Medical Physics · Physics 2026-01-27 Panpan Chen , Seonyeong Park , Gangwon Jeong , Refik Mert Cam , Umberto Villa , Mark A. Anastasio