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A fundamental challenge in artificial intelligence is learning useful representations of data that yield good performance on a downstream task, without overfitting to spurious input features. Extracting such task-relevant predictive…

Machine Learning · Computer Science 2021-06-15 Saeid Asgari Taghanaki , Kristy Choi , Amir Khasahmadi , Anirudh Goyal

The strength of multimodal learning lies in its ability to integrate information from various sources, providing rich and comprehensive insights. However, in real-world scenarios, multi-modal systems often face the challenge of dynamic…

Computer Vision and Pattern Recognition · Computer Science 2025-01-03 Xiyuan Gao , Bing Cao , Pengfei Zhu , Nannan Wang , Qinghua Hu

Vision-Language Models (VLMs), such as CLIP, have demonstrated remarkable zero-shot capabilities in various computer vision tasks. However, their application to medical imaging remains challenging due to the high variability and complexity…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xusheng Liang , Lihua Zhou , Nianxin Li , Miao Xu , Ziyang Song , Dong Yi , Jinlin Wu , Jiawei Ma , Hongbin Liu , Zhen Lei , Jiebo Luo

Drug target interaction (DTI) prediction is a cornerstone of computational drug discovery, enabling rational design, repurposing, and mechanistic insights. While deep learning has advanced DTI modeling, existing approaches primarily rely on…

Machine Learning · Computer Science 2025-11-05 Feng Jiang , Amina Mollaysa , Hehuan Ma , Tommaso Mansi , Junzhou Huang , Mangal Prakash , Rui Liao

Multimodal sequential recommendation (MSR) leverages diverse item modalities to improve recommendation accuracy, while achieving effective and adaptive fusion remains challenging. Existing MSR models often overlook synergistic information…

Information Retrieval · Computer Science 2026-01-19 Xinyi Zhang , Yutong Li , Peijie Sun , Letian Sha , Zhongxuan Han

Contrastive learning methods, such as CLIP, leverage naturally paired data-for example, images and their corresponding text captions-to learn general representations that transfer efficiently to downstream tasks. While such approaches are…

Machine Learning · Computer Science 2024-11-05 Adriel Saporta , Aahlad Puli , Mark Goldstein , Rajesh Ranganath

Heterogeneous gap among different modalities emerges as one of the critical issues in modern AI problems. Unlike traditional uni-modal cases, where raw features are extracted and directly measured, the heterogeneous nature of cross modal…

Information Retrieval · Computer Science 2015-11-19 Aiwen Jiang , Hanxi Li , Yi Li , Mingwen Wang

Recent advancements in Large Multimodal Models (LMMs) have attracted interest in their generalization capability with only a few samples in the prompt. This progress is particularly relevant to the medical domain, where the quality and…

Computation and Language · Computer Science 2024-05-06 Seonhee Cho , Choonghan Kim , Jiho Lee , Chetan Chilkunda , Sujin Choi , Joo Heung Yoon

In real world clinical environments, training and applying deep learning models on multi-modal medical imaging data often struggles with partially incomplete data. Standard approaches either discard missing samples, require imputation or…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Christoph Fürböck , Paul Weiser , Branko Mitic , Philipp Seeböck , Thomas Helbich , Georg Langs

Obtaining common representations from different modalities is important in that they are interchangeable with each other in a classification problem. For example, we can train a classifier on image features in the common representations and…

Machine Learning · Computer Science 2016-12-30 Kuniaki Saito , Yusuke Mukuta , Yoshitaka Ushiku , Tatsuya Harada

A deep learning model trained on some labeled data from a certain source domain generally performs poorly on data from different target domains due to domain shifts. Unsupervised domain adaptation methods address this problem by alleviating…

Image and Video Processing · Electrical Eng. & Systems 2019-08-30 Junlin Yang , Nicha C. Dvornek , Fan Zhang , Julius Chapiro , MingDe Lin , James S. Duncan

Multimodal deep learning has improved prognostic accuracy for brain tumours by integrating histopathology and genomic data, yet the contribution of volumetric MRI within unified survival frameworks remains unexplored. This pilot study…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Iain Swift , JingHua Ye

Malignant brain tumors have become an aggressive and dangerous disease that leads to death worldwide.Multi-modal MRI data is crucial for accurate brain tumor segmentation, but missing modalities common in clinical practice can severely…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Bingcang Huang , Kai Chen , Lin Gu , Zhe Wang , Sai Wu , Chang Yao

In this study, we present a multimodal framework for predicting neuro-facial disorders by capturing both vocal and facial cues. We hypothesize that explicitly disentangling shared and modality-specific representations within multimodal…

Audio and Speech Processing · Electrical Eng. & Systems 2026-01-13 Mohd Mujtaba Akhtar , Girish , Muskaan Singh

Causal representation learning (CRL) seeks to uncover meaningful latent variables and their corresponding causal structure from high-dimensional observational data. Although its significance, CRL identifiability remains a crucial property,…

Machine Learning · Computer Science 2026-05-20 Manal Benhamza , Marianne Clausel , Myriam Tami

Machine learning methods in healthcare have traditionally focused on using data from a single modality, limiting their ability to effectively replicate the clinical practice of integrating multiple sources of information for improved…

Machine Learning · Computer Science 2024-02-13 Felix Krones , Umar Marikkar , Guy Parsons , Adam Szmul , Adam Mahdi

Multi-modal learning plays a crucial role in cancer diagnosis and prognosis. Current deep learning based multi-modal approaches are often limited by their abilities to model the complex correlations between genomics and histology data,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Yupei Zhang , Xiaofei Wang , Fangliangzi Meng , Jin Tang , Chao Li

In this work, we perform unsupervised learning of representations by maximizing mutual information between an input and the output of a deep neural network encoder. Importantly, we show that structure matters: incorporating knowledge about…

Clinical trials are a systematic endeavor to assess the safety and efficacy of new drugs or treatments. Conducting such trials typically demands significant financial investment and meticulous planning, highlighting the need for accurate…

Machine Learning · Computer Science 2025-11-03 Tien Huu Do , Antoine Masquelier , Nae Eoun Lee , Jonathan Crowther

An ensemble of trained multimodal encoders and vision-language models (VLMs) has become a standard approach for visual question answering (VQA) tasks. However, such models often fail to produce responses with the detailed precision…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Rakesh Raj Madavan , Akshat Kaimal , Hashim Faisal , Chandrakala S
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